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Welcome to the CBIIT Speaker Series Wiki

The NCI Center for Biomedical Informatics and Information Technology (CBIIT) Speaker Series is a bi-weekly knowledge-sharing forum featuring both internal and external speakers on topics of interest to the biomedical informatics and research communities. General topics to be discussed include but are not limited to novel experimental approaches in basic research that require innovative informatics solutions; general informatics methodologies for specific tasks such as natural language processing and data exchange/integration; novel software applications (proprietary or open source); standards; ontologies; open-source development projects; human/computer interactions; future trends in biomedical informatics research and development; and CBIIT/NCIP partnerships inside and outside NCI/NIH.

Speaker Series Guidelines for Speakers: Download Word document

Please refer to the Speaker Calendar below for upcoming speakers and the "Running Updates" to the right for news and announcements.

Presentations: Please visit our Presentations page or our YouTube playlist Exit Disclaimer logo to view past speakers' presentations on video.

Location: 9609 Medical Center Drive, Rockville, Maryland 20850

Questions? Please email us at

RSS Feed:  You may subscribe to the "Notices" to the right, by using this RSS feed in your Feed Reader software.


An invitation: If you are interested in presenting your work to our diverse audience of informaticists; basic, translational, and clinical researchers; software developers; and others interested in exploring the uses of informatics in cancer research, contact Eve Shalley at or 240-276-5194.

Upcoming Speakers:

April 16: James Lacey, Ph.D., City of Hope

April 30: Lilliam Rosario, Ph.D., FDA

May 14: Andrew Su, Ph.D., Scripps Research Institute

May 28: Ada Hamosh, M.D., M.P.H., JHU School of Medicine

photo of Lilliam RosarioSYNOPSIS:

This presentation will provide an overview of how CDER’s Computational Science Center (CSC) is integrating bioinformatics and analytics into the regulatory review environment. There are a number of components that work together to enable reviewers to utilize analytical tools to assist them in answering regulatory review questions and making decisions. These components include guidance and rule development, submission and use of standardized data, data validation, analytical tools that support data exploration from the reviewer perspective, and repositories to allow data integration. The CSC is a program that provides services to CDER, and review divisions to implement the components and facilitate analytical tool skill development.

  Session details...

photo of James LaceySYNOPSIS:

Data drive research, but many studies use inefficient legacy technologies to manage their data. Better tools now exist for collecting, storing, using, and sharing data. For a large-scale new biobanking project within the prospective California Teachers Study cohort, we leveraged cloud computing and a Customer Relationship Management (CRM) system to build a novel data management system that provides real-time, on-demand access to all data, eliminates data silos, and reduces data management costs. We use mobile phones and tablets to ensure study-wide protocol compliance, guarantee high-quality data entry, and increase staff productivity. This presentation will describe why CRM and cloud computing are good for research and how we implemented our innovative system to achieve these results. We encourage other investigators to consider similar approaches and will discuss lessons learned from our experience.

  Session details...

photo of Cheryl MarksSYNOPSIS:

The NCI Mouse Models of Human Cancers Consortium has provided a focus on animal cancer models for the last 15 years. However, the program ends in 2014, and a new entity is needed to extend the outreach and educational aspects of the Consortium to support new directions for translational applications of animal models. Dr. Marks will describe a new NCI program, an open Oncology Models Forum. The Forum will provide the cancer research community with a comprehensive resource for information to guide generating, validating, and credentialing new models, informing their practical uses, advancing modeling techniques, and providing catalogs of available models-related resources, programs, and services. The goal of the Forum program will center on effective, reliable use of mice, mouse models, and human-in-mouse models in translational cancer research. Key to the success of the Forum will be use of the HubZero® platform to enable collaborators from anywhere to work together on common problems that pertain to animal models.

  Session details...

photo of Maxwell LeeSYNOPSIS:

Cancer is a complex group of diseases with many causes. Genetic changes and epigenetic alterations in somatic tissues, as well as germ line mutations or risk alleles, all contribute to cancer development and progression. Dr. Lee will present integrated studies of breast, esophageal, and gastric cancers through collaborative research with many investigators in CCR and DCEG. He will discuss a broad range of topics: from GWAS to whole genome sequencing studies; from genomics to functional studies; from genes to signature studies; from experiments to computational analyses; and from data to knowledge discovery. Dr. Lee will talk about how interweaving high-throughput data with bioinformatics analyses enables us to gain a better understanding of cancer biology and etiology.

  Session details...

Complete List of Update Posts

Speaker Calendar



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