NIH | National Cancer Institute | NCI Wiki  

What is the Gene Ontology?

The Gene Ontology (GO) project, run by the GO Consortium, is a collaborative effort to address the need for consistent descriptions of gene products in different databases. The GO collaborators are developing three structured, controlled vocabularies (ontologies) that describe gene products in terms of their associated biological processes, cellular components and molecular functions in a species-independent manner.

GO was the first external vocabulary to undergo review to become a caBIG approved terminology, and GO is an approved vocabulary for "tagging" Common Data Elements (CDEs) through the caDSR.

EVS Processing

EVS downloads the go.owl archive monthly from the Gene Ontology website and loads it into the LexEVS terminology server using the LoadOBO.sh. There is no further processing.

  • Use wget to download the obo file directly into the GO data directory. 
  • Use "more go.obo" to check the release date at the top of the file
  • Use "mv go.obo go_MonthYYYY.obo" to rename the file with the version
  • Update the manifest and metadata with the version
  • Load using LoadOBO.sh


  • No labels