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Dr. Sandra A. Mitchell is a research scientist in the Outcomes Research Branch of the Applied Research Program, Division of Cancer Control and Population Sciences, at the National Cancer InstituteNCI. Her work focuses on the development and testing of measures of symptom burden, physical function, and sleep and fatigue in patients with cancer, and the application of these outcomes to evaluate therapeutic response and treatment toxicity in clinical trials. Her methodologic interests include latent variable mixture modeling to characterize underlying heterogeneity, and as well as analysis and interpretation issues of surrounding patient-reported outcomes, including health-related quality of life.

A board certified acute-care nurse practitioner, Dr. Mitchell maintains a clinical practice as an oncology nurse practitioner Oncology Nurse Practitioner with the Experimental Transplantation and Immunology Branch, NCI Intramural Program, focusing on long-term survivors of allogeneic hematopoietic stem cell transplantation with Chronic Graftchronic graft-Versusversus-Host Disease. Dr. Mitchell host disease. She also serves as the Program Director program director for the development and testing of PRO-CTCAE, a new measurement system to integrate patient - reporting of symptomatic adverse events into cancer clinical trials.

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