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Role CodesGene-Disease and Gene-Compound Role Codes most often describe that a gene is associated with a disease or compound (e.g.,
Role DetailsGene-Disease and Gene-Compound Role Details most often provide precise descriptions of the association of a gene term and a corresponding disease or compound term. These Details can also describe relevant features of the role of a particular gene (e.g.,
Cell Line and Negation Indicators Anchor | Indicators | IndicatorsThe binary indicators
yes ) or other source, such a human subject, animal model, or primary cells (no ). The cell line indicator is the text contents of the XML CelllineIndicator element and the celllineStatus attribute of the caBIO Evidence class.
yes ), or whether there was a true relationship between them (no ). Occasionally, the curators did not set a negation indicator (- ). The negation indicator is the text contents of the XML NegationIndicator element and the negationStatus attribute of the caBIO Evidence class.
Status FlagsThe curators set flags to denote the state of annotations of a gene term or of a particular sentence. Gene Status Flags
Gene Status FlagsGene Status Flags describe whether annotations for all of the sentences for a given gene term are complete and whether the gene term has been withdrawn from EntrezGene. All low frequency sentence count genes were finished, whereas some high frequency sentence count genes were not (#HFGs). The status of a specific gene is found in the text contents of the XML
Sentence Status Flags
Sentence Status FlagsUnlike gene status flags, which can cover many sentences associated with a single gene, Sentence Status Flags describe the curator's findings for a specific sentence. Sentences can be true positives, false positives, unclear, or redundant. The status of a specific gene is found in the text contents of the XML
Comments
CommentsOften, the expert curators made free-text comments on records within the Gene-Disease or Gene-Compound databases. Comments included, but were not limited to, notations of genetic anomalies (e.g., loss of heterozygosity, polymorphisms, or aberrant methylation), additional disease information, name of the non-human organism from which the experimental data were collected, information on the cell line or other notable reagents used in the execution of the experiment, and other miscellaneous information. Any comments on a sentence are found in the text contents of the XML |