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Technical Description: The scientist in this case is trying to develop a workflow that will assist biomarker discovery research. S/he first needs to discover the services that provide biospecimen information with the phenotype s/he is looking for (e.g. HER2/neu negative stage I breast cancer) and then the microarray experiment information. Next he needs to discover service that will help him analyzing the microarray experiments or the type of data he has. Then he needs to create a workflow (orchestrate services) where the input is a phenotype for biospecimens and output is a set of gene of interest. These steps require the support for standard terminologies (and services) and syntaxes to best describe the services' behavior and static data. Furthermore the Furthermore they require inference engines that relates the semantic and syntactic metadata for the data produced (i.e. outputs) and consumed (i.e. inputs) by the services should be enough the inputs/outputs of the services to "assist" scientist to identify what service can be part of the workflow.

Cross References:

• Support development of workflows:
  • https://cabig-kc.nci.nih.gov/Vocab/forums/viewtopic.php?f=43&t=146
  • https://wiki.nci.nih.gov/x/VAhyAQ
  • https://wiki.nci.nih.gov/x/FxRlAQ
• ICR IRWG Requirements
  https://cabig-kc.nci.nih.gov/Vocab/forums/viewtopic.php?f=43&t=146

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