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  • Function BIRN Data Repository - http://fbirnbdr.nbirn.net:8080/BDR/
    • Contains 5 data sets according to the BIRN data page (but it's actually 4). 
    • On the home page it displays a description of each data set and then presents pre-packaged data files in a drill down tree style menu which lists what appears to be individual patients in some cases, individual image studies in others.
    • Querying across the data is possible using meta data.  It does not appear query against DICOM tags is possible.
    • The site itself seems to be a custom web site, not something that could be easily used for other archives.
    • Downloads happen in the browser.  You choose what you want to download, it is processed on the server and there is an alert that notifies you when your "job" is ready for download.  Testing a 100mb patient download I was notified pretty quickly that my job was done, but getting the job page to load took about a minute before I was presented with a small table of information and buttons to actually download the file.  Pressing the download button resulted in saving a .TAR file to my computer.  TAR structure contained many subdirectories sorted by study then series and so on.  Images contained DCM file extension and there were also a couple XML files included with some meta-data.
    • The data sets include the following (but the last one is not yet posted, may never be since this was done in 2007):
      • BrainScape Resting State fMRI Dataset 1 - This dataset includes seventeen healthy subjects with four resting state fixation scans plus one T1 scan and one T2 scan.
      • BrainScape Resting State fMRI Dataset 2 - This dataset includes ten healthy subjects scanned 3 times with 3 conditions: eyes open, eyes closed, and fixating in addition to two anatomical scans (T1 and T2).
      • Neuroimaging Calibration Study (Phase II) - The FBIRN multi-site dataset of subjects with schizophrenia and controls includes functional MRI images, behavioral data, demographic, and clinical assessments on 253 subjects from around the US.
      • Traveling subjects study (Phase I) - This dataset includes five healthy subjects imaged twice at each of ten FBIRN MRI scanners on successive days.
  • NIRL Imaging Database - http://nirlarc.duhs.duke.edu/nirle/
    • Uses XNAT for the archive software (unsure what version or if any major customizations were made)
    • Contains both image data and meta-data
    • Includes the following data sets:
      • Efficient Longitudinal Upload of Depression in the Elderly (ELUDE) - The ELUDE dataset is a longitudinal study of late-life depression at Duke University. There are 281 depressed subjects and 154 controls included (435 total patients). An MR scan of each subject was obtained every 2 years for up to 8 years (total of 1093 scans). Clinical assessments occurred more frequently and consists of a battery of psychiatric tests including several depression-specific tests.
      • Multisite Imaging Research In the Analysis of Depression (MIRIAD) - A multiple institution study of structural MRI, including raw PD and T2 MRIs and derived measures of white matter changes, basal ganglia and other regions. Demographic and extensive clinical assessment data is available for each case. (100 patients)
  • Central XNAT- http://central.xnat.org/

NAMIC

NAMIC Image Gallery: http://www.na-mic.org/publications/gallery

Lung Cancer Alliance: Give A Scan

http://www.giveascan.org/

NDAR

http://ndar.nih.gov/ndarpublicweb/aboutNDAR.go

Pediatric MRI Data Repository

From their homepage-

*Give A Scan* is the world's first patient-powered, publicly available archive of images and clinical data on lung cancer patients. All the data has been donated by patients in order to encourage more researchers to focus on lung cancer and to accelerate progress in the early detection, diagnosis and treatment of lung cancer which is now the leading cause of cancer death worldwide.

As of August 2010 the archive contains 9 "communities" which appear to be 9 patients with lung cancer totaling approximately 1GB of data.  The site provides some meta data information about the images and clinical info about the subjects.  Images are hosted in DICOM format.  The archive can be browsed by Community/patient/study/series or searched by modality and other image meta data.

NA-MIC

National Alliance for Medical Image Computing (NA-MIC) Image Gallery: http://www.na-mic.org/publications/gallery

As of August 2010 this consisted of ~376 images.  All images appear to be JPGs or similar compressed file types rather than actual DICOM.  The purpose of this gallery seems to be to create a repository for images, charts, and figures referenced in publications submitted to NA-MIC's publication database (http://www.na-mic.org/publications).   Images can be browsed by patient/study/series or searched by modality and a number of other image based features.

National Database for Autism Research (NDAR)

http://ndar.nih.gov/ndarpublicweb/aboutNDAR.go

According to http://ndar.nih.gov/ndarpublicweb/aboutNDAR.go#federation-

The Pediatric MRI Data Repository will be the first in this series to be made available to ASD researchers, in the summer of 2010. At that time, investigators will be able to perform a single query in the NDAR portal to view results across multiple datasets.

The original Pediatric MRI Data Repository is located at https://nihpd.crbs.ucsd.edu/nihpd/info/index.html. Access to the data requires filling out multiple forms and faxing them to an office at NIH to receive permission. I have not yet requested access at this time to find out exactly what's in the archive, however some information about their quality control processes reveal a little about the image protocols and can be learned about here: https://nihpd.crbs.ucsd.edu/nihpd/info/dataquality_accesscontrol.html

NIH Image Bank

http://media.nih.gov/imagebank/index.aspx

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