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For trials using ICD-O-3 codes, use the Subject Disease Code position for ICD-O-3 Site and Morphology (which must include Histology and Behavior codes). If When you use both Site and Histology codes, separate them by a semi-colon as per the example below.

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SDC Disease Code:
PATIENTS,"NCI-2011-03861",8732228,84124,,196311,1,9,1,20060809,CALGB,149280,,,,,,,,,,238.7,,
ICD-O-3 Site and Histology Codes:
PATIENTS,"NCI-2011-03861",8732228,84124,,196311,1,9,1,20060809,CALGB,149280,,,,,,,,,,C64.9;8000/3,,
ICD-O-3 Site Code only:
PATIENTS,"NCI-2011-03861",8732228,84124,,196311,1,9,1,20060809,CALGB,149280,,,,,,,,,,C64.9;,,
ICD-O-3 Histology Code only:
PATIENTS,"NCI-2011-03861",8732228,84124,,196311,1,9,1,20060809,CALGB,149280,,,,,,,,,, ;8000/3,,