Page History
(TBD: Most of the links on this page point to pages in wiki spaces, visible only to GP-CFW_ADMINS and GP-CFW_nanoTAB_DEV. I propose to restrict viewing of this page to match.)
The caNanoLab project is actively involved in a variety of efforts supporting the development of standards for representing nanomaterials and their characterizations as applied to the field of nanomedicine. The caNanoLab project participates in the Nanotechnology Working Group (Nano WG) which is chartered to integrate nanotechnology information and tools to aid discovery and clinical translation in the cancer research community leveraging infrastructure components. The primary objectives of the Nano WG are to:
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The caNanoLab project worked with the Nano WG to develop a Nanotechnology Data Sharing Standards document which identifies common data elements leveraged across nanotechnology resources.
Nanotechnology Data Sharing Standards document includes support for:
- Nanomaterials and their Composition - Nanomaterials (for example, dendrimer) and their associated properties (for example, branch, generation) and composing elements (for example, core). Includes functionalizing entities (for example, small molecule, antibodies) associated with the nanomaterial that allow the material to function as a targeting, therapeutic, and/or diagnostic agent.
- Physico-Chemical Characterizations - Assay conditions and measurements associated with the physical (for example, size, molecular weight) and chemical (for example, surface chemistry) properties of nanomaterials.
- In Vitro Characterizations - Assay conditions and measurements that assess a nanomaterial's interaction with cellular components including cytotoxicity and blood contact properties.
- In Vivo Characterizations - Characterizations performed on nanomaterials to determine the safety, efficacy, pharmacokinetics, and toxicology properties of nanomaterials in animal models so that nanomaterials can be transitioned for use in clinical applications.
- (TBD: Add bullet point for Synthesis hereWill the Nanotechnology Data Sharing Standards document be updated to mention Synthesis?)
NanoParticle Ontology
caNanoLab consumes of and contributes to the NanoParticle Ontology (NPO)
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Artifacts from the sub-group are available on the ISA-TAB-Nano project project site.