- is NCI's reference terminology and core biomedical ontology, covering some 150,000 key biomedical concepts with a rich set of terms, codes, 120,000 textual definitions, and over 400,000 inter-concept relationships. NCIt combined and extended core NCI terminologies within a scientifically and technically rigorous framework. NCIt is now a broadly shared coding and semantic infrastructure resource – over half of NCIt concepts include content explicitly tagged by one or more EVS partners (see the ).
- whose 7whose 8,500015,000 800 terms are mapped to 3to 3,200653,000 463 concepts representing their shared meanings. NCIm contains most terminologies used by NCI for clinical care, translational and basic research, and provides a rich source of definitions, synonyms, codes, and other information. NCIm starts from a subset of NLM's UMLS Metathesaurus, and modifies and extends it with many additional sources. provides a broad, concept-based mapping of terms from over 101 biomedical terminologies,
- : EVS licenses, processes and makes available individually through EVS systems, many other terminologies of special interest to NCI and the research community. EVS has helped create, harmonize with, and publish several of these terminologies. publishes all terminologies hosted by NCI EVS in an integrated environment, providing search, cross-links, and a user friendly interface to ICD-9-CM, CTCAE, MedDRA, SNOMED CT, NDF-RT, GO, and many other terminologies and ontologies used by NCI and its partners.
- : Pairwise mappings between several supported terminologies have also been created and published to support data translation and cross-reference. As with standalone terminologies above, such mappings generally reflect special EVS community interests and collaborations.
- : EVS works with many partners to create and support standardized terminology for biomedical coding. Hundreds of NCIt subsets and other code lists are maintained by EVS, and most are now available as CTS 2 value sets following the draft and Data Standards . In caDSR, they provide a pre-curated standard set of meanings for use by metadata curators. More than 1100 than 1900 value sets are currently defined in EVS, most as subsets of NCIt covering a range of standards from many EVS partners. Key EVS supported terminology standards include:
than 23than 24,000 475 FDA terms and codes are stored in NCIt.: EVS is working with the U.S. Food and Drug Administration (FDA) to develop and support controlled terminology in several areas. More
: The Clinical Data Interchange Standards Consortium (CDISC) -- an international, non-profit organization that develops and supports global data standards for medical research -- has chosen EVS as its terminology partner.
: The National Council for Prescription Drug Programs (NCPDP) creates and promotes the transfer of data related to medications, supplies, and services through the development of standards and industry guidance, and now uses NCIt in two of its standards.
: The National Institute of Child Health and Human Development (NICHD) and EVS are working with numerous contributors from national and international academic, clinical and research institutions to provide standardized terminology for coding pediatric clinical trials and other research activities.