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Date

Attendees

Committee MemberPresentAbsent
Kuffel, Gina (NIH/NCI) [C]
X

Unknown User (leblancak)



Otridge, John (NIH/NCI) [C]



Kim, Erika (NIH/NCI) [E]


Sommers, Connie (NIH/NCI) [E]



Debbie Knapp

Toby Hecht

Unknown User (parchmentr)



Goals

  • Discuss updates to ICDC and define emerging strategies and priorities

SharePoint Site

https://nih.sharepoint.com/sites/NCI-CBIIT-FNL-ICDC-ICDCLeadershipGroups

Outstanding Action Items

Agenda

ItemWhoTalking Points
DGAB Updates

Kuffel, Gina (NIH/NCI) [C]

  • 33 TB of data are now available in ICDC (five-fold increase since January)
  • TCL01 study has been loaded into our Dev tier
  • 1st PRECINCT study has been approved by the DGAB & SAC
  • PRECINCT has used templates available from the ICDC Data Model Explorer (DME) for the fist ever load of a study via submitter-generated loading files
    • Initial version of data is available in Dev tier
    • Waiting on significant data updates from study owners before proceeding with a reload of the study in updated and somewhat expanded form
  • Will has volunteered his time to create a scientific use case from ICDC data
BPSC Updates

Kuffel, Gina (NIH/NCI) [C] 

  • 2022 BPSC Review Article
    • Outline completed
    • Preliminary section assignments have been made
    • Communicate deadline of August 1, 2022
    • Communicate that future funding hinges upon this publication
June Steering Committee Updates

Unknown User (parchmentr)

  • Minutes to be posted
  • Next meeting is ?
ICDC Site Updates

Kuffel, Gina (NIH/NCI) [C]

  • Next software release for ICDC targets July 7th
    • ICDC Static News Page
    • Data Availability Landscape (DAL)
    • Gene annotations for JBrowse
ICDC Next Phase Planning

Unknown User (hechtt)

Minutes (Not Verbatim)


Previous ICDC Use Cases from Steering Committee

1. Genomic correlates across platforms (DNA, RNA, protein).

...

8. Develop biomarkers of response and resistance in humans by analyzing the responses and genomic signatures in dogs.

Previous Meeting Minutes (Not Verbatim)

Toby - Can canine bladder cancer be a good model for invasive human bladder cancer? Maybe running differential expression in dogs at various stages vs. human data at different stages of disease obtained from the GDC and then comparing expression patterns and gene signatures. Real focus is comparative genomics.

...