Uploading Investigation-Study-Assay tab-delimited (ISA-TAB) Uploading investigation data to the CSSI DCC Portal allows you to curate, manage, and reuse datasets in a standards-compliant way. The ISA-TAB Tab specification

An ISA archive is a compressed (.ZIPzip) file containing multiple text files and data files. Each tab-delimited text file in an ISA -TAB file archive describes the structure, meaning the column headers and row values when considered in spreadsheet format, of the investigation, study, and assay components of the archive. The data files correspond to each assay and are included in the archive in their native format, for example, Microsoft Excel. An ISA -TAB file archive may also contain images and other files.

Users who are logged in to the CSSI DCC Portal can upload ISA-TAB data. Before you upload a ISA data to this repository, you must create and configure it using open-source software

Registering to Use the CSSI DCC Portal

Before you can log in for the first time, you must register.

To register on the CSSI DCC Portal

1. Navigate to the CSSI DCC Portal.
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2. Click Login.
   The Please Sign In page appears.
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3. Click Register.
   The Registration page appears.
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4. Provide information in all of the following required fields:
   • First name
   • Last name
   • Institution
   • Email address
   • Password
   • Confirm password
5. If you want to upload investigation data to the CSSI DCC portal in the future, select the I would like to upload investigation data box. Doing so ensures that your future submissions are correctly tracked.
6. Select the I'm not a robot box.
7. Click Register.
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8. Check your inbox for an email with the subject line "CSSI DCC Account Activation." Click the link in the email to complete account activation.
9. Get started using the CSSI DCC Portal.

Logging In to the CSSI DCC Portal

Before you can upload investigation data, you must register and then log in.

You do not need to log in to browse, search, and download investigation data.

To log in to the CSSI DCC Portal

1. Navigate to the CSSI DCC Portal.
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2. Click Login.
   The Please Sign In page appears.
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3. Enter your email address and password you specified when you registered.
4. Click Sign In.
   The CSSI DCC Portal home page appears.

Uploading an ISA-TAB File to a Template

To upload an ISA-TAB archive file

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Select the file you want to upload by either

• dragging and dropping the ISA-TAB archive file from your computer to the File box, or

• clicking Add files to navigate to where the file is stored.
  Template files must be in one of the following archive formats: .zip,.rar,.tar,.gz. The file can be no larger than 500 MB.

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• Upload as new: A new file that has not been uploaded before.
• Replace existing file: This file replaces an existing one associated with this template.
  Next version: This file becomes the active version of the file associated with the selected template. All previous versions of the template are accessible from the Template List and you can make any of them active or inactive as needed.

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• Private restricts access only to you, when you are logged in
• Public makes the file available to both registered and unregistered users.
• Custom 

Uploading investigation data requires a logged-in CSSI DCC user account with permission to upload. For details on requesting permission to upload data, refer to Managing Your Account. 

You can upload a single ISA archive and save it to a folder. If you need an administrator to delete an investigation version from a folder, contact the Center for Strategic Initiatives (CSSI) Data Coordinating Center (https://cssi-dcc.nci.nih.gov/cssiportal/contactus) or click the Contact Us link at the bottom of any DCC page.

The following page family describes how to upload investigation data and request open access for your uploaded data.

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