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Federated discovery, searching, and data aggregation

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A user is interested in seeing any microarrays performed against lung samples obtained from non-smokers with stage 3 lung cancer. She queries Mayo and OSU because both hospital systems have been running independent lung cancer trials. Realizing that Mayo and OSU are working independently, she puts a flag into her search criteria indicating that cross institute joins are not required. The web application creates the necessary queries, one joining across OSU and one joining across Mayo. For the Mayo join, data returns from caTissue followed by data from the Mayo caArray service. The application recognizes that these two datasets can be joined together based on the specimen ID and returns results to the user. These results are displayed to the user along with a message stating that [1] institute has not returned data to date. A minute or two later, the data from the missing institute returns and is appended to the results from Mayo that the user is currently browsing through.

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