Page History

ICDC Incoming Data Submission Requests

• Potential new submission requestrequest
  • University of Zurich
• STS01
  • Soft tissue sarcoma study from Colorado State University
  • 29 cases
  • Genomics, Transcriptomics, Immunology 
    
  • Status: DGAB is reviewing
• OSA04 OSA04: 
  • Osteosarcoma study from Auburn University
  • 7 cases
  • Clinical and Transcriptomic data
  • Status: Kick off call to be planned

ICDC Studies in Active Submission 

COTC021 

• "Evaluation of Orally Administered mTOR inhibitor Rapamycin in Dogs in the Adjuvant Setting with Osteosarcoma" 
• 152 cases
• Dr. Amy LeBlanc 
• Status: The Since study, case and sample records were loaded in early September a reconciliation was performed to ensure accuracy. Sequencing files and file transfer manifest have been transferred to bucket pending validation. 2 study-level files need to be added to the bucket.

COTC022

• "A Contemporaneous Controlled Study of the Standard of Care (SOC) in Dogs with Appendicular Osteosarcoma" 
• 157 cases
• Status: Sample and file records have been received. The study has been loaded onto the QA environment and is currently in testing.

UBC03 

• "Transcriptomic analyses of early-stage bladder cancer in Scottish Terriers detected through screening" 
• Dr. Debbie Knapp 
• Status: Multiple versions of metadata have been received and the final version is in review. Waiting on the File Transfer ManifestAll data loading template files and file transfer manifest have been received, validation is pending. Waiting on file transfer.

OSA02 

• "Immune Pathways and TP53 missense mutations are associated with longer survival in canine osteosarcoma" 
• 117 cases
• Dr. Dawn Duval 
• Status: Version 1 of metadata Template data loading files have been received and reviewed. Version 2 is expected soon to address validation errors. The study has been loaded onto the Dev tier. Files from the submitter bucket are being transferred into the ICDC production bucket. 

PRECINCT01 

• "Inhaled IL-15 Immunotherapy for Treatment of Lung Metastases" 
• UC Davis 
• 21 cases 
• Status: 21 pathology reports and 5 study-level files, including Nanostring-based evaluation of cytokine levels, have been received and indexed by DCF. Adverse event data has been ingested. Application-level testing revealed several software bugs related to download of the clinical data and fixes are pending by the ICDC team.  

PRECINCT02 

• "Novel treatments for Diffuse large B cell lymphoma (DLBCL) in dogs" 
• Tufts University 
• 49 cases 
• Status: Adverse event data has been received and ingested. Visit, vital signs and physical exam data was received and revealed validation errors. Version 2 of these loading files has been received.Lab exam and extent of disease data to be received.