 |
Page History
...
| Section | ||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Semantic Infrastructure Domain User Story 6:
Discover and orchestrate services to achieve LS research goals; e.g. start with a hypothesis, identify relevant services that provides the necessary analysis and data, create the worklow/pipeline, report findings.
Domain Description Revised From ICRi Use Cases
A scientist is trying to identify a new genetic biomarker for HER2/neu negative stage I breast cancer patients. The scientist queries for HER2/neu negative tissue specimens of Stage I breast cancer patients using services at his/her cancer center that also have corresponding microarray experiments. Analysis of the microarray experiments identify genes that are significantly over-expressed and under-expressed in a number of cases. The scientist decides that these results are significant, and related literature suggest a hypothesis that gene A may serve as a biomarker in HER2/neu negative Stage I breast cancer. To validate this hypothesis in a significant number of cases the scientist needs a larger data set, so he queries for all the HER2/neu negative specimens of Stage I breast cancer patients with corresponding microarray data and also for appropriate control data from other cancer centers. After retrieving the microarray experiments the scientist analyzes the data for over-expression of genes A.
...
Forum Request
Requirements Input
Requirements Input
ICR ICRi Use Cases
Related Services
| Scrollbar | ||
|---|---|---|
|
