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The Code Map Services project was in part funded by the through Office of the Assistant Secretary for Planning and Evaluation (ASPE) for the Patient-Centered Outcomes Research Institute (PCORI)Trust (PCORTF). This project is phase III of the Common Data Model Harmonization (CDMH) project. Through the use of common data models (CDMs), scientists conduct analysis of real-world data which is critical for healthcare and clinical research. CDMs standardize the structure, format, and terminologies for data, so researchers can collaborate, share data, and conduct analyses across different datasets. Code Map Services provide researchers with an automated tool to transform (machine to machine) data collected and stored in one CDM format into another CDM formatamong CDMs and/or data standards:

• The National Patient-Centered Clinical Research Network

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  (PCORnet)
• The Observational Medical Outcomes Partnership

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  (OMOP)
• FDA Sentinel Initiative

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• Health Level Seven International

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  (HL7) Fast Health Interoperability Resources

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  (FHIR) US Core Profiles V7 (based on V6

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  (based on United States Core Data for Interoperability USCDI)
• Informatics for Integrating Biology & Bedside

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  / Accrual to Clinical Trials

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  (i2b2/ACT)
• TriNetX

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• Clinical Data Interchange Consortium

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  (CDISC) Study Data Tabulation Model

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  (SDTM)

Code Map Services establish a source of truth within caDSR (the Cancer Data Standards Registry and Repository (caDSR, a shared metadata mapping repository) by using standards-based semantic annotations for establishing model-to-model equivalents. Mappings can evolve and be versioned over time, thereby improving and expanding functionality with each release.

This project will harmonize semantics across multiple CDMs and data standards to provide researchers in federal agencies and academia with access to observational real-world data from various data sources (such as electronic health records and administrative claims) and from different research networks. The data elements in these models will be registered in caDSR as Common Data Elements (CDEs).

Code Map Services advance the ability to conduct high-quality and efficient PCOR patient-centered outcomes research and other types of research studies. Along with publicly available transformation rules, caDSR will enable Transformation tool vendors to provide services to the CDM communities to extend the accessibility of their data to other communities, vastly expanding the impact of their work.

caDSR II Features features include:

• Model Import import and Versioningversioning
• Creation of Model Mapping and Transformation Rules model mapping and transformation rules including value mappings for data coded using “local codes”
• Services to support registration of CDEs for new models
• Application Programming Interfaces (APIs) and a File Transfer Protocol (FTP) site for retrieving Model model information and Mappings as csv filesmappings
• Limited NCI Metathesaurus and / NCI Thesaurus terminology cross-walk mapping tables for data coded using a subset of selected standard terminologiesAPIs for retrieving mapping information

For details, refer to the following pages: