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Semantic Infrastructure 2.0
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needs
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to
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address
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metadata
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and
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terminology
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related
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requirements
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from
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the
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life
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sciences
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domain,
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enabling
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interoperability
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both
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between
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different
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sub-domains
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within
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life
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sciences,
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and
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between
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life
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sciences
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and
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other
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domains
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in
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caBIG®
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such
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as
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clinical
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trials
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and
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electronic
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health
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records.
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While
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life
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sciences
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will
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leverage
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common
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semantic
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functionalities
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such
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as
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ECCF
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registry,
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modeling,
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forms,
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behavioral
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semantics,
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terminology
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and
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value
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sets,
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there
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are
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aspects
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specific
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to
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the
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domain
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that
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need
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to
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be
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addressed,
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including
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but
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not
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limited
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to:
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- High
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- change
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- semantic
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- environment
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- where
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- novel
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- concepts
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- which
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- have
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- not
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- been
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- previously
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- characterized
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- need
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- to
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- be
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- described
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- Computational
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- or
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- analytical
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- workflow
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- compositions
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- processing
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- raw
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- data
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- to
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- derive
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- knowledge
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- Description
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- of
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- statistical
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- processes
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- related
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- to
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- computational
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- processses
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- to
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- achieve
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- the
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- above
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- Working
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- with
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- the
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- platform,
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- enabling
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- semantic
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- description
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- of
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- raw
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- data
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- potentially
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- of
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- large
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- volume
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- (e.g.
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- next-gen
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- sequencing,
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- imaging
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- data)
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- Support
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- of
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- provenance
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- to
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- trace
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- data
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- ownership
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- and
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- also
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- to
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- achieve
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- reproducibility
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- of
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- analytical
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- results
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As
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a
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starting
...
point,
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the
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requirements
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gathering
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effort
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will
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be
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informed
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by
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past
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and
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current
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related
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efforts
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in
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caBIG®,
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such
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as
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the
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recent
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Semantic
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Infrastructure
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Requirements
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Elicitation
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effort,
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the
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caBIO
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ECCF
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service
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specification
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project
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on
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molecular
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and
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pathway
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annotation
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services
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from
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the
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Integrated
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Cancer
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Research
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(ICR)
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Workspace,
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the
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Annotated
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Information
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Model
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(AIM)
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from
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the
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In-Vivo
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Imaging
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(IMAG)
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Workspace
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for
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both
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radiological
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and
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pathologic
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images,
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and
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work
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on
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"Dynamic
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Extensions"
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from
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the
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Tissue
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Banks
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and
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Pathology
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Tools
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(TBPT)
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Workspace.
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Nevertheless,
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we
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anticipate
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significant
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further
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input
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from
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community
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feedback
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based
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on
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this
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roadmap
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document,
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and
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from
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the
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life
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sciences
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workgroup
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within
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the
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Semantic
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Infrastructure
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2.0
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Inception
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Effort
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which
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will
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involve
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both
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requirements
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gathering
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and
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prototype
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tool
...
building.
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