A goal of the Cancer Data Standards Registry and Repository (caDSR) program is to define a comprehensive set of standardized metadata descriptors for cancer research data for use in information collection and analysis.
Various NCI offices and partner organizations have developed the content of the caDSR by registration of data elements based on data standards, data collection forms, databases, clinical applications, data exchange formats, UML models, and vocabularies.
Based on the ISO/IEC 11179 model for metadata registration, information about names, definitions, permissible values, and semantic concepts for common data elements (CDEs) have been recorded. caDSR tools are available to create, locate, and use the metadata to support finding and understanding research data.
The metadata information in the caDSR is developed by groups or organizations divided into domain-specific work areas called Contexts. A Context
Administrator for each group provides oversight for creation, maintenance, and designation of CDEs within the Context. A list
of contact information for Steward/Context Administrators, Stewardship Organization/Curators and
Embedded Curators (doc) is available.
The current Contexts in the caDSR are listed below with the Context Administrator for each (updated 06/29/2021). Note - In the event the Steward/CA and/or SO/Curator leaves your organization, please contact the caDSR.RA@mail.nih.gov with new POC name and email if available.
Link to Website
NCI Cancer Biomedical Informatics Grid
|Adult Brain Tumor Consortium||ABTC||Sung Tse (interim)|
|Yeshiva University Albert Einstein Cancer Center||AECC|
|AIDS Malignancy Consortium||AMC||Damon Collie|
|Biorepositories and Biospecimen Research Branch||BBRB||Ping Guan|
|Breast Oncology Local Disease||BOLD||Jennifer Hayes|
NCI Core Infrastructure
Clincal Data Interchange Standards Consortium
|Cancer Clinical Trials Group||CCTG||Chad Winch|
|Centers for Disease Control and Prevention/Public Health Information Network||CDC/PHIN||Denise Warzel|
NCI Cancer Imaging Program
|Cancer Immunotherapy Trials Network||CITN|
|Children's Oncology Group||COG|
NCI Clinical Trial Evaluation Program
|Eastern Cooperative Oncology Group - Amercian College of Radiology Research Network||ECOG-ACRIN|
ECOG - Jannett Garrido
ACRIN - Lindsey Dymond
NCI Early Detection Research Network
National Cancer Research Institute (UK)
|NCI Genomic Data Commons||GDC||Maureen Ryan (interim)|
|The Integrated Cancer Repository for Cancer Research||iCaRe2||Gwen Deen|
Georgetown University Lombardi Cancer Center
|NCI Molecular and Cellular Characterization||MCL||Kristen Anton|
|NCI Data Standards||NCI Data Standards||caDSR Harmonization Team|
National Cancer Informatics Program
|Norton Healthcare - Norton Cancer Institute||NHC-NCI|
National Heart, Lung, and Blood Institute
|National Institute of Child Health and Human Development||NICHD||Wendy Zhang|
|National Institute on Drug Abuse||NIDA||Brian Campbell|
National Institute of Dental and Craniofacial Research
|NCI Network Rave Data Standards||NRDS||Ginger Riley|
|NRG Oncology Group (formerly GOG)|
|Office of Cancer Clinical Proteomics Research||OCCPR|
Mathangi Thiagarajan - CPTACChris Kinsinger - PDC
|NCI Office of Cancer Genomics||OCG||Subhashini Jagu|
|Oregon Health and Science University||OHSU-Knight||Sung Tse|
|NCI Office of National Coordinator SDC Project||ONC SDC Project||Brenda Duggan|
|PCORnet Common Data Model (CDMH Phase I)||PCORTF CDM||Denise Warzel|
|Pediatric Brain Tumor Consortium||PBTC||Gwen Deen|
|Phenotypes and Exposures||PhenX||Helen Pan|
|Precision Medicine Initiative||PMI||Ginger Riley|
NCI Population Science and Cancer Control
Gwen Deen (interim)
NCI Specialized Programs of Research Excellence
|University of Southern California Norris Comprehensive Cancer Center||USC/Norris||Gwen Deen (interim)|
Business Rules and Best Practices
The Context Administrators have agreed to business rules for development of caDSR content. The rules outline best practices for creation, assignment of metadata statuses, and maintenance of the various metadata components.
Harmonization of caDSR Content
The Context Administrators/Stewards work together to coordinate and harmonize metadata development efforts so common building blocks for data capture and reporting can be created. The goal is to ensure that shareable CDEs are not redundant across contexts and are based on the consensus of participating Contexts. To help minimize redundancy and duplication of CDEs across Contexts, the Context Administrators encourage reuse, or designation, of existing CDEs by other Contexts. Often an item is a candidate for reuse if minor edits can be made. If changes are needed to caDSR content, please contact the owning Context Curator.
NCI Data Standards
The NCI, together with its partners in the
user community, is actively developing CDEs and standard vocabularies to be used as metadata descriptors for NCI-sponsored research and for caCORE-
NCI applications. Workgroup and Content Meetings are regularly held to identify subject areas for standardization, develop CDEs and supporting documentation, and present proposed data standards to the
user community for review. The
standards that have been adopted and those currently under review may be seen on the caBIG®-NCI Data Standards page.