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This document summarizes the changes in the caBIG® Annotation and Image Markup (AIM) model between version 3, revision 11 and the current version, which is 4, revision 43. AIM 4.0 is also referred to as the AIM foundation model.

You can download the AIM 3.0 model from

The most significant changes from version 3.0 to 4.0 of the AIM model is the use of ISO 21090 data types, a caBIG® mandate, and the introduction of AIM Statements. An AIM Statement describes a relationship of a finding found on an image or series of images. It represents a relationship between the subject and object entities in the AIM foundation model.