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The Cancer Imaging Archive (TCIA)

NBIA

NIAMS

XNAT Central

Image Data Archive

Function BIRN Data Repository

Give A Scan

Optical Society of America (OSA)

Insight Journal (MIDAS)

National Database for Autism Research (NDAR)

Pediatric MRI Data RepositoryFITBIR

Supporting Institution(s)

Cancer Imaging Program

Cancer Imaging Program, caBIG

NIAMS, caBIG

WUSTL, BIRN

Lab of NeuroImaging UCLA (LONI)

FBIRN Institutions

Lung Cancer Alliance, Kitware

Optical Society of America, Kitware

Kitware, Insight Software Consortium

NIH, NIMH, NINDS, NICHD, NIEHS

NIH, NIMH, NICHD, NIDA, NINDSNINDS, DoD

Content Type

In Vivo Cancer Imaging, phantom imaging and related metada (see full Collection list)

In Vivo Cancer Imaging (see full collection list)

Osteoarthritis

Biomedical images, meta data, other phenotypic data (bevhioralbehavioral, clinical, etc)

ADNI (Alzheimers),
CRYO (histology),
ICBM (Brain mapping),
AIBL (Autralian Aging)

FMRI/MRI images, behavioral data, and clinical data

Patient-contributed Lung Cancer Medical scans

Optical, digital holography, 2D/3D modalities, etc

Biomedical images and , meta data, and journal articles

Autism - standard phenotypic data, imaging and genomic/pedigree data related to human subjects

Normal brain development

 

TBI related data: imaging, phenotypic and some genomics; human but expanding to preclinical models

Archive Software

NBIA, AIM Data Service (XML image metadata), and a Clinical Data relational database

NBIA

NBIA

XNAT

Image Data Archive

Human Imaging Database (HID)

MIDAS

MIDAS

MIDAS

customSame as NDAR (custom)Biomedical Research Informatics Computing System (BRICS) NIH developed – custom

Login account required

Yes.  Accounts are free and available to anyone. Click here to register.

For advanced site features or limited access data sets, but is not required for accessing public data. Click here to register.

Yes. Click here to register.

For accessing limited access data sets, but not for public data

Yes, via web https://ida.loni.ucla.edu/login.jsp.

No (email requested)

No

For accessing limited access data sets, but not for public dataFor accessing limited access data sets, but not for public data

Only for submitting data.

Yes

YesYes

Explicit data sharing policy

Yes, with options for uploading fully open or limited access data sets

Yes, with options for uploading fully open or limited access data sets

Yes, found here

No, data is made public or restricted as specified by the user who uploads it.

Yes, found here

All data is made publicly accessible.

All data is made publicly accessible.

 

 Yes, found here.

All data is made publicly accessible (varying licenses)

Yes, found here

Similar to NDAR but there is no explicit policyYes, https://fitbir.nih.gov/jsp/about/policy.jsp

Number of Registered Users (or NA)

2,607

2,712

46

~1,000

>1,000

N/A

N/A

  

2,657

60 for data access
100-200 for data submission

~30

15 – just starting

Accepting new data

Yes, proposals are accepted via email and reviewed monthly by the TCIA Advisory Committee. Acceptance criteria is summarized here: Requesting Permission to Upload your Data.

Yes, with approval from NCI CBIIT

More data is being added as part of the official initiative, but external proposals are not being accepted.

Yes, users can register accounts and upload data

Yes, see section 9 in the Appendix of the LONI Policies & Procedures

Yes, https://www.birncommunity.org/about/contact/

Yes, through Lung Cancer Alliance. Learn more here.

Yes, through the new data may be added as part of future Optical Society of America publications are released.

Yes, users can register accounts and upload data.

Yes, learn more here

NoYes, FITBIR has established a two-tiered submission strategy to ensure high quality and to provide maximum benefit to investigators.  See the Data Submission Procedures for more information.

Central curation/review

Yes, a multiple tiered de-identification and QC process is utilized involving both human review and systematic analysis.  The process is summarized in detail on the TCIA De-Identification Knowledge Base and What to Expect as an Image Provider.

Yes, performed by CBIIT staff

Yes, performed by NIAMS staff.

No

Yes, project-specific QC

Yes, project-specific

Yes, performed by Lung Cancer Alliance

Yes, performed by the Optical Society of America

Yes, some QC performed by Kitware staff and peer reviews.  Most data is de-identified by the submitter prior to upload.

Sites do their own de-identification any way they prefer, so long as it meets their IRB's approval. 

Pre-validation is performed to ensure all data conforms/harmonizes to the autism data dictionary. QA is also performed by NDAR staff to check for identifiable information.

Archived project, no longer receiving new data.Yes, pre-validation is performed to ensure all data conforms to the NINDS CDEs. QA is also performed by staff to check for personal identifiable information.

Availability/Uptime

~99%, hosted on a redundant production system at WUSTL

~99%, hosted on a redundant production system at NCI CBIIT

~99%, hosted on a redundant production system at NCI CBIIT

~99%

Continuous (no exact % specified)

Continuous (no exact % specified)

~99%~99.9%, hosted on a production server at Kitware

~99.9%, hosted on a production server at OSA

~99%, hosted on a production server at Kitware

~99%, imaging data hosted on Amazon and metadata hosted by NIH.

~99%, hosted by NIH.~99%, hosted by NIH.

Project- or Collection- based groupings?

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

NoYes

Size of Current Volume

TCIA: 1.8 TB
NLST-LSS: 6.5 TB
NLST-ACRIN: 4.8 TB

Total: 13.1 TB

~2TB

~7.5TB

1 TB

0.7 PB

~2TB

33GB

~50GB

~60GB

~2TB

~2TB0.5TB

Number of patients/subjects with imaging

TCIA: 3,685
NLST-LSS: 17,043
NLST-ACRIN: 9,211

Total: 29,939

4,920

4,796

3,494

> 120,000

~300

37

 

 N/A

> 200, plus some non-patient data

2500 NDAR

 

550 (migrated into NDAR)200

Number of DICOM Tags query-able

~90 via NBIA

~90

~90

~50

50

0

22 (imaging parameters in query interface)

 

 N/A

22 (imaging parameters in query interface)

9, with full listing from data dictionary. (4 NDAR, 5 Pediatric MRI)

9, with full listing from data dictionary. (4 NDAR, 5 Pediatric MRI)10
Metadata AvailabilityWide variety of clinical, genetic, and image segmentation/annotation available is available for various data sets.  Full summary can be viewed here in the "Supporting Data Available" column.Some limited metadata available for specific collectionsNone

Various clinical and other metadata

Biospecimen, clinical, pathological, neuropsychiatric, and demographic.Yes, extensive

Some unstructured clinical data such as patient age, cancer stage, recurrence, and treatment information.

  Associated articles, figures, publication-specific metadata, etcUnstructured clinical data as well as publication-specific metadata

NDAR contains all human subjects data related to autism research funded by the NIH and others.  Outside of the NDAR data dictionary, Metadata supporting project definition and research results are provided (see data from papers). 

 

 

Yes, all metadata is collected using NINDS CDEs

Data submission/download methods

Submission via DICOM or HTTPS protocols using CTP. Download via Java Webstart client. A REST API is in development with an expected public release in the summer of 2013.

Submission via DICOM or HTTPS protocols using CTP. Download via Web (zip), FTP, Java Webstart client

Submission via DICOM or HTTPS protocols using CTP. Download via Web (zip), FTP, Java Webstart client

Submission via Web UI or DICOM protocol.  Download via Web (zip) or Java applet.

Secure web upload

Downloads via Web UI, Submissions via https://www.birncommunity.org/about/contact/

Submission via Web UI,
Download via Web (zip).

Submission via Web UI,
Download via Web (zip).

Submission via Web UI, DICOM push, MIDASDesktop, WebDAV.


Download via Web (zip), MIDASDesktop or WebDAV

A custom Java Webstart application allows SFTP transfers.  MIPAV is offered as an optional method for de-identification.  Submission is harmonized to the autism data standard using custom data validation software.  Download methods include multithreaded download or push to cloud computational pipeline.

Not applicable.They can use MIPAV for submitting images. Submissions must conform to FITBIR Data Dictionary (NINDS CDEs). A custom Java Webstart application allows SFTP transfers.

Helpdesk Support

Yes, the TCIA Helpdesk supports both end users and submitters. They provide phone and email support during regular business hours Mon-Fri.

Yes, CBIIT Application Support

Yes, CBIIT Application Support

Via XNAT discussion group

dba@loni.ucla.edu

Yes, via https://www.birncommunity.org/about/contact/

No official helpdesk info found on the site.  Some email support may be available.

 

 Technical issues can be sent to midas@public.kitware.com or click here for  Administrative support and other questions.

Contact infobase@osa.org.

Contact midas@public.kitware.com

Yes, available at ndarhelp@mail.nih.gov.

Yes, pedsmri@mail.nih.gov.Yes, FITBIR-help@mail.nih.gov

Affiliation with Journal

No

No

No

No

Yes, NeuroImage

No

No

Yes , Optics Info Base

Yes, Insight Journal

No

NoNo

Intended Audience(s)

Cancer researchers, engineers and developers, professors

Cancer researchers and anyone interested in testing the functionality of the NBIA software.

Osteoarthritis researchers

All imaging research

Neuroimaging and genetics research

Neuroimaging research

Lung cancer researchers

 

 Optical Society of America subscribers

All imaging research

Autism researchers (clinical/phenotype/genomic), both those receiving autism related NIH grants and other investigators sponsored by an NIH recognized institution with a current federal-wide assurance.

Neuroscientists interested in normative brain study of child development.TBI researchers

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