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SYNOPSIS:

Markers are becoming more important in NCI-supported clinical trials.  These trials are becoming increasingly oriented toward precision medicine.  Unfortunately, Program Staff do not have access to a database that tracks such markers to make sure their use can be managed.   The Center for Coordinating Clinical Trials (CCCT) was mandated to create the Clinical Trials Reporting Project (CTRP) to coordinate tracking all elements of the clinical trials.  CTRP now contains nearly 7,000 trials with roughly half of them including markers on all patients; 12% of said trials have integral markers that are essential for performance of the trial, e.g., mutations for eligibility for targeted therapies.  The presentation will cover the CTRP Marker database and its potential as a resource for staff and potentially the public.

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