A goal of the Cancer Data Standards Registry and Repository (caDSR) program is to define a comprehensive set of standardized metadata descriptors for cancer research data for use in information collection and analysis.
Various NCI offices and partner organizations have developed the content of the caDSR by registration of data elements based on data standards, data collection forms, databases, clinical applications, data exchange formats, UML models, and vocabularies.
Based on the ISO/IEC 11179 model for metadata registration, information about names, definitions, permissible values, and semantic concepts for common data elements (CDEs) have been recorded. caDSR tools are available to create, locate, and use the metadata to support finding and understanding research data.
The metadata information in the caDSR is developed by groups or organizations divided into domain-specific work areas called Contexts. A Context Curator for each group provides oversight for creation, maintenance, and designation of CDEs within the Context. A list of contact information for Context Administrators and Curators is available.
The current Contexts (updated 06/11/2013) in the caDSR are listed below with the Context Administrator for each.
|Yeshiva University Albert Einstein Cancer Center||AECC||Gwen Deen (interim)|
NCI Cancer Biomedical Informatics Grid
NCI Core Infrastructure
NCI Center for Cancer Research
|Centers for Disease Control and Prevention/Public Health Information Network||CDC/PHIN||Denise Warzel|
Clincal Data Interchange Standards Consortium
NCI Cancer Imaging Program
NCI Clinical Trial Evaluation Program
NCI Division of Cancer Prevention
|Eastern Cooperative Oncology Group - Amercian College of Radiology Research Network||ECOG-ACRIN||Tina Taylor|
NCI Early Detection Research Network
Georgetown University Lombardi Cancer Center
National Heart, Lung, and Blood Institute
|National Institute of Child Health and Human Development||NICHD||Steven Hirschfeld|
|National Institute on Drug Abuse||NIDA||Brian Campbell|
National Institute of Dental and Craniofacial Research
|National Institute of Neurological Disorders and Stroke||NINDS||Joanne Odenkirchen|
NCI Population Science and Cancer Control
NCI Specialized Programs of Research Excellence
|University of Southern California Norris Comprehensive Cancer Center||USC/Norris||Gwen Deen (interim)|
Business Rules and Best Practices
The Context Administrators have agreed to business rules for development of caDSR content. The rules outline best practices for creation, assignment of metadata statuses, and maintenance of the various metadata components.
Harmonization of caDSR Content
The Context Administrators work together to coordinate and harmonize metadata development efforts so common building blocks for data capture and reporting can be created. The goal is to ensure that shareable CDEs are not redundant across contexts and are based on the consensus of participating Contexts. To help minimize redundancy and duplication of CDEs across Contexts, the Context Administrators encourage reuse, or designation, of existing CDEs by other Contexts. Often an item is a candidate for reuse if minor edits can be made. If changes are needed to caDSR content, please contact the owning Context Curator.
NCI Data Standards
The NCI, together with its partners in the user community, is actively developing CDEs and standard vocabularies to be used as metadata descriptors for NCI-sponsored research and for caCORE-NCI applications. Workgroup and Content Meetings are regularly held to identify subject areas for standardization, develop CDEs and supporting documentation, and present proposed data standards to the user community for review. The data standards that have been adopted and those currently under review may be seen on the caBIG®-NCI Data Standards page.