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Cancer is a complex group of diseases with many causes. Genetic changes and epigenetic alterations in somatic tissues, as well as germ line mutations or risk alleles, all contribute to cancer development and progression. Dr. Lee will present integrated studies of breast, esophageal, and gastric cancers through collaborative research with many investigators in CCR and DCEG. He will discuss a broad range of topics: from GWAS to whole genome sequencing studies; from genomics to functional studies; from genes to signature studies; from experiments to computational analyses; and from data to knowledge discovery. Dr. Lee will talk about how interweaving high-throughput data with bioinformatics analyses enables us to gain a better understanding of cancer biology and etiology. |
BIO:
Dr. Maxwell Lee is the head of the high-dimension data analysis group at NCI’s Center for Cancer Research (CCR). Dr. Lee’s group conducts collaborative research with many investigators at CCR and the Division of Cancer Epidemiology and Genetics (DCEG). The group focuses on bioinformatics analyses of high-throughput data. His research spans multiple domains, including cancer genomics and epigenomics, population genetics and epidemiology, allelic-specific gene expression and epigenetic modifications, and computational methods. Dr. Lee has published more than 60 peer-reviewed papers. He serves as an Associate Editor for BMC Cancer and is on the committees of TCGA DAC, iNCI DAC, CCRIFX RPC, and NCIP High-throughput Molecular Data Working Group.
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