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Material Source Name---The name of the nanomaterial or small molecule associated with the Material File. There can be only one Material Source Name per column. This concept is introduced in ISA-TAB-Nano to identify source name of the material. (ISA-TAB Extension for ISA-TAB-Nano)

Study

The STUDY This section allows for the description of one or more studies conducted as part of an investigation. An example of the STUDY section is in TABLE 6 on the Investigation File Examples page. There are 11 concepts used in the STUDY section, seven of which are taken from ISA-TAB and four are introduced in ISA-TAB-Nano. These concepts are described below:

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Study File Name---The name of the ISA-TAB-Nano study file, which lists information about the biological specimens (cells, tissues, organs, animal model, body fluids), nanoparticles; small organic molecules, and other types of samples assayed in a study. There can be only one file name per cell.

Study Design Descriptors

The STUDY DESIGN DESCRIPTORS This section allows for the identification of design type of the study. An example of the STUDY DESIGN DESCRIPTORS section is in TABLE 7 on the Investigation File Examples page. There are 3 concepts used in the STUDY DESCRIPTORS section. These concepts are taken from ISA-TAB.

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Study Design Type Term Source REF---The name which identifies the source from where the term for study design type is selected. This name should match one of the names entered in the term source name field.

Study Publications

The STUDY PUBLICATIONS This section allows for the identification of articles (published) associated with the study. An example of the STUDY PUBLICATIONS section is in TABLE 8 on the Investigation File Examples page. . This section uses seven ISA-TAB concepts.

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Study Publication Status Term Source REF---The name which identifies the source from where the term for study publications status is selected. This name should match one of the names entered in the term source name.

Study Factors

The STUDY FACTORS This section allows for the identification of factors associated with the study. An example of the STUDY FACTORS section is in TABLE 9 on the Investigation File Examples page. This section has four concepts taken from ISA-TAB.

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Study Factor Type Term Source REF---The name which identifies the source from where the term for study factor type is selected. This name should match one of the names entered in the term source name field.

Study Assays

The STUDY ASSAYS This section allows for the identification of type of measurement and the type of technology used for the measurement in an assay that is part of a study. An example of the STUDY ASSAYS section is in TABLE 10 on the Investigation File Examples page. The STUDY ASSAYS section has 11 concepts. Out of these, 8 concepts are taken from ISA-TAB. The remaining concepts are introduced in ISA-TAB-Nano.

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Study Assay File Name--- Name of the ISA-TAB-Nano Assay file corresponding to the study assay. This is a required field. There can be only one assay file name per cell.

Study Protocols

The STUDY PROTOCOLS This section allows for the identification of the type of protocols, and the parameters and components of a protocol used in a study. A protocol describes the formal plan of an experiment or research activity, including the objective, rationale, design, materials and methods for the conduct of the study; intervention description, and method of data analysis. An example of the STUDY PROTOCOLS section is in TABLE 11 on the Investigation File Examples page. There are 14 concepts in this section taken from ISA-TAB.

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Study Protocol Components Type Term Source REF--- The name which identifies the source from where the term for study protocol component type is selected. This name should match one of the names entered in the term source name field.

Study Contacts

The STUDY CONTACTS This section allows the identification of the point of contact for a study. An example of the STUDY CONTACTS section is in TABLE 12 on the Investigation File Examples page. The STUDY CONTACTS section has 11 ISA-TAB concepts.

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