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After defining the particle properties, continue to define define Biopolymer information.

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Biopolymer

A biopolymer nanoparticle is a type of polymer that is produced by living organisms. In the context of nanotechnology, a biopolymer can also be a nanomaterial entity or a functionalizing entity.

Define biopolymer properties.

FieldDescription
Name

Enter the name of the biopolymer.

Bipolymer type

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Biopolymer type
Biopolymer type

Sequence

Using the appropriate format, enter the complete sequence of the biopolymer.

Continue below to define carbon nanotube information.

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Fill in the carbon nanotube properties as needed.

FieldDescription
Average Length

Enter the average length of the nanotube.

Length Unit

Select or enter the measurement unit type for the average length measurement of the nanotube.

Chirality

The spatial position or orientation of functional groups located within a molecule. Enter information about the chirality in the nanotube and its effect on the orientation of functional groups located on the particle.

Diameter

Enter the measurement of the nanotube diameter, as measured from one side of the tube wall through the center of the nanotube to the opposite point on the circumference.

Diameter Unit

Enter the measurement unit type of the nanotube diameter.

Wall Type

Select the appropriate description of the nanotube wall.

    • DWNT (Double-Wall Nanotube) Nanotube wall consists of two layers of graphitic carbon.
    • MWNT (Multiple-Wall Nanotube) Nanotube consists of single-walled nanotubes layered inside each other
    • SWNT (Single-wall Nanotube) Wall consists of a single layer of graphitic carbon

Continue below to define dendrimer information.

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Fill in the dendrimer properties.

FieldDescription
Branch

Branches are molecules that branch off of the core (like tree branches). Enter a description that represents the number of branches in the dendrimer.

Generation

Generations are shells layered on the core of a dendrimer. Dendrimers consist of layers of chemical shells built on a core module. Each shell consists of two chemicals in the same order (A-B) and each shell is called a generation. The generations are labeled in decimal to illustrate the shell layering/consistency. For example, Generation 2.5 (G2.5) = 1 shell of A-B (1), surrounded by a second shell of A-B (2), topped off with only one chemical A within the shell (.5). As such, the layering structure would be (A-B, A-B, A) = 2.5.

List the generations reflected in this dendrimer.

Continue below to define Emulsion information.

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Fill in the emulsion properties as needed.

FieldDescription
Is Polymerized*

Specify whether the composition is polymerized. Polymerization consists of enzymatic reactions that link a series of monomers, forming a polymerized compound (polymer), usually of high molecular weight, by combination of simpler molecules (monomers).

Polymer Name*

Enter the name of the polymer suspended in the emulsion.

Continue below to define Fullerene information.

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Fill in the liposome properties as needed. After defining the particle properties, continue to define Metal Particle information.

FieldDescription
Polymer NameEnter the name of the liposome polymer.
Is Polymerized

Polymerization consists of enzymatic reactions that link a series of monomers, forming a polymerized compound (polymer), usually of high molecular weight, by combination of simpler molecules (monomers).

Select Yes or No, reflecting whether or not the liposome is polymerized.

Continue below to define metal particle information.

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Define the polymer properties.

FieldDescription
InitiatorEnter the agent that initiated the polymerization. Examples are free radicals or peroxide.
Is crosslinkedCrosslinking is a covalent bond between two polymers or two different regions of the same polymer. Select Yes or No, indicating whether the polymer is crosslinked.
Crosslink DegreeEnter the percentage level of covalent linkage in the polymer.

Continue below to define quantum pot information.

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Other options
Other options

FieldDescription
Composing Element Type*Select from the drop-down list the type of composing element comprising this nanomaterial (required).
Chemical Name*Enter the chemical name given to the atomic or molecular structure that composes the center of the nanoparticle (required).
Crosslink DegreeEnter the percentage level of covalent linkage in the polymer.
PubChem Data Source/PubChem ID

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PubChem data source
PubChem data source

Amount/Amount Unit

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Amount unit
Amount unit

Molecular Formula Type

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Molecular formula type
Molecular formula type

Molecular FormulaEnter the chemical formula of the nanoparticle.
DescriptionEnter a description for the composing element.
Inherent Function

Inherent function is the characteristic behavior of a sample that results from the chemical and physical composition and properties of the entity.

Click the Add button to expand the page where you can enter this information.

Function Type

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Function type
Function type

DescriptionEnter any additional function information for the nanomaterial entity that the form does not already include.

Click Save to add the inherent function details to the nanomaterial entity or Cancel to just close the window.

After defining composing elements, continue to define Add add supporting documentation files.

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Adding a File

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Include Page
Other options
Other options

FieldDescription
Chemical NameEnter the chemical name for the functionalizing entity whose type you just selected.
PubChem Data Source/PubChem ID

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PubChem data source
PubChem data source

Amount/Amount Unit

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Amount unit
Amount unit

Molecular Formula Type

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Molecular formula type
Molecular formula type

Molecular FormulaEnter the chemical formula of the functionalizing entity.
Activation MethodSelect from the drop-down menu the method used to activate the functionality of the sample.
Activation EffectEnter the functional effect of the entity.
DescriptionEnter any additional composition information that the form does not include.

When you finish, click Submit to save the data to the sample or click Reset to clear all fields on the form.

Continue to define   Functionalizing Entity Propertiesfunctionalizing entity properties.

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Defining [Functionalizing Entity type] Properties
Anchor
functionalizingEntityProperties
functionalizingEntityProperties

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Other options
Other options

FieldDescription
AntibodySelect from the following fields:
  • Type:   Select from the drop-down list the type of antibody functioning for this sample.
  • Isotype:   Select from the drop-down list the isotype for this antibody:IgA
  • Species:  Select from the drop-down list the animal species from which the antibody was derived.
Biopolymer

Select from the following fields.

  • Include Page
    Biopolymer type
    Biopolymer type
  • Sequence: Using the appropriate format, enter the complete sequence of the biopolymer.
Small MoleculeAdd an Alternate Name for the Small Molecule.

Continue to define Function  function information.

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Defining Function Information

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Include Page
Other options
Other options

FieldDescription
Function Type

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Function type
Function type

DescriptionEnter any additional composition information that the form does not include.

When you finish, click Save. In the Navigation Tree, a hyperlink for the new Composition characterization is added under Functionalizing Entity.

Continue to  Add to add files, if needed.

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  1. Once you enter the essential nanomaterial entity and functionalizing entity information under the Composition category, click the Add button corresponding to Chemical Association on the All tab or select the Chemical Association tab itself where you can click the Add button.
  2. The page that opens is organized into three sections. Select from the drop-down list the Association Type (required). Options include:
    Description: Enter any additional information that describes the chemical association of the two elements.
  3. In the Elements Information section, both Element boxes select the nanomaterial or functionalizing entities for which you are defining the chemical association. These have been previously defined for the sample you are annotating. For each selection you make, another drop-down list appears displaying entities relating to your previous selection. Make the appropriate selections in each.The arrow between the Element text boxes symbolizes the association between the two.
  4. In the File section, click Add to expand the page where you can add one or more files whose data is relevant to the nanomaterial entity or the derivation of its data.

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  1. Click Composition on the Navigation Tree, and click the Composition File tab.
  2.  Composition File Add button.
    Next to Composition File click Add.
  3. Select Upload, then click the Browse button to navigate to the report or publication to be associated with the sample,
    – OR –
    Click Enter File URL and enter the URL where the document is located.
  4. For the file to be added, specify or enter the following:
    1. File Type (required): Document, Graph, Image, Spreadsheet
    2. File Title (required)
    3. Keywords to associate with the file
    4. Description: Enter any additional information for the file that the form does not already include.
  5. In the Visibility field, select the group(s) to be granted access to the selected file.
  6. Click Submit to add the referenced file(s) to the sample.

    After adding one or more files, continue the process described in  Adding Chemical Association Composition Annotations.

    Tip

    You can add as many files as you wish.

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