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As a starting point, the requirements gathering effort will be informed by past and current related efforts in caBIG®, such as the recent Semantic Infrastructure Requirements Elicitation effort, the caBIO ECCF service specification project on molecular and pathway annotation services from the Integrated Cancer Research (ICR) Workspace, the Annotated Information Model (AIM) from the In-Vivo Imaging (IMAG) Workspace for both radiological and pathologic images, and work on "Dynamic Extensions" from the Tissue Banks and Pathology Tools (TBPT) Workspace.  Nevertheless, we anticipate significant further input from community feedback based on this roadmap documentsdocument, and from the life sciences workgroup within the Semantic Infrastructure 2.0 Inception Effort which will involve both requirements gathering and prototype tool building.