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HTTP Method POST

URL /trials/complete

Request Body

XML document with

CompleteTrialRegistration

MIME Type: application/xml

Response Body

XML document with

TrialRegistrationConfirmation

MIME Type: application/xml.

HTTP Response Code

200. Success

400. Validation error

401. Invalid username/password or insufficient permissions to access the service.

404. One of the Persons/Organizations acting on the trial was not found in PO

500. Internal server error

Examples

URL: https://trials.nci.nih.gov/services/trials/complete

Request (referring to existing Organizations and Persons by ID):

Code Block

language	html/xml
collapse	true

<?xml version="1.0" encoding="UTF-8"?>
<tns:CompleteTrialRegistration xmlns:tns="gov.nih.nci.pa.webservices.types"
                               xmlns:tns1="gov.nih.nci.po.webservices.types.trimmed" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
                               xsi:schemaLocation="gov.nih.nci.pa.webservices.types ../../src/resources/ws.xsd ">

    <tns:leadOrgTrialID>REST00001</tns:leadOrgTrialID>
    <tns:clinicalTrialsDotGovTrialID>NCT12345678</tns:clinicalTrialsDotGovTrialID>
    <tns:dcpIdentifier>DCP123</tns:dcpIdentifier>
    <tns:otherTrialID>OTHER00000000001</tns:otherTrialID>
    <tns:title>REST Trial Test</tns:title>
    <tns:phase>I</tns:phase>
    <tns:pilot>false</tns:pilot>
    <tns:accrualDiseaseTerminology>SDC</tns:accrualDiseaseTerminology>
    <tns:primaryPurpose>Other</tns:primaryPurpose>
    <tns:primaryPurposeOtherDescription>PP Other Description</tns:primaryPurposeOtherDescription>
    <tns:interventionalDesign>
        <tns:secondaryPurpose>Other</tns:secondaryPurpose>
        <tns:secondaryPurposeOtherDescription>Secondary Other Descr</tns:secondaryPurposeOtherDescription>
    </tns:interventionalDesign>
    <tns:leadOrganization>
        <tns:existingOrganization>
            <tns:poID>1</tns:poID>
        </tns:existingOrganization>
    </tns:leadOrganization>
    <tns:pi>
        <tns:existingPerson>
            <tns:poID>1</tns:poID>
        </tns:existingPerson>
    </tns:pi>
    <tns:sponsor>
        <tns:existingOrganization>
            <tns:poID>2</tns:poID>
        </tns:existingOrganization>
    </tns:sponsor>
    <tns:responsibleParty>
        <tns:type>Sponsor</tns:type>
    </tns:responsibleParty>
    <tns:summary4FundingSponsor>
        <tns:existingOrganization>
            <tns:poID>3</tns:poID>
        </tns:existingOrganization>
    </tns:summary4FundingSponsor>
    <tns:programCode>REST_PG01</tns:programCode>
    <tns:fundedByNciGrant>false</tns:fundedByNciGrant>
    <tns:grant>
        <tns:fundingMechanism>B01</tns:fundingMechanism>
        <tns:nihInstitutionCode>AA</tns:nihInstitutionCode>
        <tns:serialNumber>111111</tns:serialNumber>
        <tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
        <tns:fundingPercentage>100.0</tns:fundingPercentage>
    </tns:grant>
    <tns:trialStatus>In Review</tns:trialStatus>
    <tns:whyStopped>tns:whyStopped<whyStopped>If study stopped, enter the reason why.</tns:whyStopped>
    <tns:trialStatusDate>2014-07-15</tns:trialStatusDate>
    <tns:trialStartDate type="Actual">2014-07-15</tns:trialStartDate>
    <tns:primaryCompletionDate type="Anticipated">2018-07-15</tns:primaryCompletionDate>
    <tns:completionDate type="Anticipated">2018-07-15</tns:completionDate>
    <tns:ind>
        <tns:number>111111</tns:number>
        <tns:grantor>CDER</tns:grantor>
        <tns:holderType>NIH</tns:holderType>
        <tns:nihInstitution>NEI</tns:nihInstitution>
        <tns:expandedAccess>true</tns:expandedAccess>
        <tns:expandedAccessRecord>NCT12345688</tns:expandedAccessRecord>
        <tns:expandedAccessType>Available</tns:expandedAccessType>
        <tns:exempt>true</tns:exempt>
    </tns:ind>
    <tns:ide>
        <tns:number>222222</tns:number>
        <tns:grantor>CDRH</tns:grantor>
        <tns:holderType>NCI</tns:holderType>
        <tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
        <tns:expandedAccess>true</tns:expandedAccess>
        <tns:expandedAccessRecord>NCT12345688</tns:expandedAccessRecord>
        <tns:expandedAccessType>Available</tns:expandedAccessType>
        <tns:exempt>true</tns:exempt>
    </tns:ide>
    <tns:regulatoryInformation>
        <tns:country>USA</tns:country>
        <tns:authorityName>Federal Government</tns:authorityName>
        <tns:fdaRegulatedDrug>true</tns:fdaRegulatedDrug>
        <tns:fdaRegulatedDevice>true</tns:fdaRegulatedDevice>
        <tns:approvalClearance>false</tns:approvalClearance>
        <tns:marketSurveillance>true</tns:marketSurveillance>
        <tns:usaExport>true</tns:usaExport>
        <tns:fdaRegulated>true</tns:fdaRegulated>
        <tns:section801>true</tns:section801>
        <tns:delayedPosting>false</tns:delayedPosting>
        <tns:dataMonitoringCommitteeAppointed>true</tns:dataMonitoringCommitteeAppointed>
    </tns:regulatoryInformation>
    <tns:protocolDocument filename="protocol.pdf">dGVzdA==</tns:protocolDocument>
    <tns:irbApprovalDocument filename="irb.pdf">dGVzdA==</tns:irbApprovalDocument>
    <tns:participatingSitesDocument
            filename="sites.pdf">dGVzdA==</tns:participatingSitesDocument>
    <tns:informedConsentDocument filename="consent.pdf">dGVzdA==</tns:informedConsentDocument>
    <tns:otherDocument filename="other.pdf">dGVzdA==</tns:otherDocument>
    <tns:category>Externally Peer-Reviewed</tns:category>
    <tns:trialOwner>denis.krylov@semanticbits.com</tns:trialOwner>
</tns:CompleteTrialRegistration>

Request (non-interventional trial):

Code Block

language	html/xml
collapse	true

<tns:CompleteTrialRegistration xmlns:tns="gov.nih.nci.pa.webservices.types"
	xmlns:tns1="gov.nih.nci.po.webservices.types.trimmed" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
	xsi:schemaLocation="gov.nih.nci.pa.webservices.types ../../src/resources/ws.xsd ">
	
	<tns:leadOrgTrialID>UPCC 34890534</tns:leadOrgTrialID>
	<tns:clinicalTrialsDotGovTrialID>NCT01994850</tns:clinicalTrialsDotGovTrialID>
	<tns:otherTrialID>818280234</tns:otherTrialID>
	<tns:title>A Phase I/II Study Of Brentuximab Vedotin In Combination With Multi-Agent Chemotherapy</tns:title>
	<tns:phase>I</tns:phase>
	<tns:pilot>false</tns:pilot>
	<tns:accrualDiseaseTerminology>ICD10</tns:accrualDiseaseTerminology>
	<tns:primaryPurpose>Other</tns:primaryPurpose>
	<tns:primaryPurposeOtherDescription>Determine maximum tolerated dose (MTD) of brentuximab vedotin</tns:primaryPurposeOtherDescription>
	<tns:nonInterventionalDesign>
		<tns:trialType>Observational</tns:trialType>
		<tns:studyModelCode>Other</tns:studyModelCode>
		<tns:studyModelCodeOtherDescription>studyModelCode other</tns:studyModelCodeOtherDescription>
		<tns:timePerspectiveCode>Other</tns:timePerspectiveCode>
		<tns:timePerspectiveCodeOtherDescription>timePerspectiveCode other</tns:timePerspectiveCodeOtherDescription>
	</tns:nonInterventionalDesign>
	<tns:leadOrganization>
		<tns:existingOrganization>
			<tns:poID>1</tns:poID>
		</tns:existingOrganization>
	</tns:leadOrganization>
	<tns:pi>
		<tns:existingPerson>
			<tns:poID>1</tns:poID>
		</tns:existingPerson>
	</tns:pi>
	<tns:sponsor>
		<tns:existingOrganization>
			<tns:poID>2</tns:poID>
		</tns:existingOrganization>
	</tns:sponsor>
	<tns:responsibleParty>
		<tns:type>Sponsor</tns:type>
	</tns:responsibleParty>
	<tns:summary4FundingSponsor>
		<tns:existingOrganization>
			<tns:poID>3</tns:poID>
		</tns:existingOrganization>
	</tns:summary4FundingSponsor>
	<tns:programCode>PG00001</tns:programCode>
	<tns:fundedByNciGrant>false</tns:fundedByNciGrant>
	<tns:grant>
		<tns:fundingMechanism>B09</tns:fundingMechanism>
		<tns:nihInstitutionCode>AA</tns:nihInstitutionCode>
		<tns:serialNumber>111111</tns:serialNumber>
		<tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
		<tns:fundingPercentage>100.0</tns:fundingPercentage>
	</tns:grant>
	<tns:trialStatus>In Review</tns:trialStatus>
	<tns:whyStopped></tns:whyStopped>
	<tns:trialStatusDate>2014-07-15</tns:trialStatusDate>
	<tns:trialStartDate type="Actual">2014-07-15</tns:trialStartDate>
	<tns:primaryCompletionDate type="Anticipated">2016-07-15</tns:primaryCompletionDate>
	<tns:completionDate type="Anticipated">2016-07-15</tns:completionDate>
	<tns:ind>
		<tns:number>111111</tns:number>
		<tns:grantor>CDER</tns:grantor>
		<tns:holderType>NIH</tns:holderType>
		<tns:nihInstitution>NEI</tns:nihInstitution>
		<tns:expandedAccess>true</tns:expandedAccess>
		<tns:expandedAccessType>Available</tns:expandedAccessType>
		<tns:exempt>true</tns:exempt>
	</tns:ind>
	<tns:ide>
		<tns:number>222222</tns:number>
		<tns:grantor>CDRH</tns:grantor>
		<tns:holderType>NCI</tns:holderType>
		<tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
		<tns:expandedAccess>true</tns:expandedAccess>
		<tns:expandedAccessType>Available</tns:expandedAccessType>
		<tns:exempt>true</tns:exempt>
	</tns:ide>
	<tns:regulatoryInformation>
		<tns:country>USA</tns:country>
		<tns:authorityName>Federal Government</tns:authorityName>
		<tns:fdaRegulated>true</tns:fdaRegulated>
		<tns:section801>true</tns:section801>
		<tns:delayedPosting>true</tns:delayedPosting>
		<tns:dataMonitoringCommitteeAppointed>true</tns:dataMonitoringCommitteeAppointed>
	</tns:regulatoryInformation>
	<tns:protocolDocument filename="protocol.pdf">dGVzdA==</tns:protocolDocument>
	<tns:irbApprovalDocument filename="irb.pdf">dGVzdA==</tns:irbApprovalDocument>
	<tns:participatingSitesDocument
		filename="sites.pdf">dGVzdA==</tns:participatingSitesDocument>
	<tns:informedConsentDocument filename="consent.pdf">dGVzdA==</tns:informedConsentDocument>
	<tns:otherDocument filename="other.pdf">dGVzdA==</tns:otherDocument>
	<tns:category>Externally Peer-Reviewed</tns:category>
	<tns:trialOwner>submitter-ci@example.com</tns:trialOwner>
</tns:CompleteTrialRegistration>

Request (trial where submission to ClinicalTrials.gov is not required):

Code Block

language	html/xml
collapse	true

<tns:CompleteTrialRegistration xmlns:tns="gov.nih.nci.pa.webservices.types"
	xmlns:tns1="gov.nih.nci.po.webservices.types.trimmed" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
	xsi:schemaLocation="gov.nih.nci.pa.webservices.types ../../src/resources/ws.xsd ">	

	<tns:leadOrgTrialID>UPCC 34890534</tns:leadOrgTrialID>
	<tns:clinicalTrialsDotGovTrialID>NCT01994850</tns:clinicalTrialsDotGovTrialID>
	<tns:otherTrialID>818280234</tns:otherTrialID>
	<tns:title>A Phase I/II Study Of Brentuximab Vedotin In Combination With Multi-Agent Chemotherapy</tns:title>
	<tns:phase>I</tns:phase>
	<tns:pilot>false</tns:pilot>
	<tns:accrualDiseaseTerminology>ICD10</tns:accrualDiseaseTerminology>
	<tns:primaryPurpose>Other</tns:primaryPurpose>
	<tns:primaryPurposeOtherDescription>Determine maximum tolerated dose (MTD) of brentuximab vedotin</tns:primaryPurposeOtherDescription>
	<tns:interventionalDesign>
		<tns:secondaryPurpose>Other</tns:secondaryPurpose>
		<tns:secondaryPurposeOtherDescription>Secondary Other Description</tns:secondaryPurposeOtherDescription>
	</tns:interventionalDesign>
	<tns:leadOrganization>
		<tns:existingOrganization>
			<tns:poID>1</tns:poID>
		</tns:existingOrganization>
	</tns:leadOrganization>
	<tns:pi>
		<tns:existingPerson>
			<tns:poID>1</tns:poID>
		</tns:existingPerson>
	</tns:pi>	
	<tns:summary4FundingSponsor>
		<tns:existingOrganization>
			<tns:poID>3</tns:poID>
		</tns:existingOrganization>
	</tns:summary4FundingSponsor>
	<tns:programCode>PG00001</tns:programCode>
	<tns:fundedByNciGrant>false</tns:fundedByNciGrant>
	<tns:grant>
		<tns:fundingMechanism>B09</tns:fundingMechanism>
		<tns:nihInstitutionCode>AA</tns:nihInstitutionCode>
		<tns:serialNumber>111111</tns:serialNumber>
		<tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
		<tns:fundingPercentage>100.0</tns:fundingPercentage>
	</tns:grant>
	<tns:trialStatus>In Review</tns:trialStatus>
	<tns:whyStopped></tns:whyStopped>
	<tns:trialStatusDate>2014-07-15</tns:trialStatusDate>
	<tns:trialStartDate type="Actual">2014-07-15</tns:trialStartDate>
	<tns:primaryCompletionDate type="Anticipated">2016-07-15</tns:primaryCompletionDate>
	<tns:completionDate type="Anticipated">2016-07-15</tns:completionDate>
	<tns:ind>
		<tns:number>111111</tns:number>
		<tns:grantor>CDER</tns:grantor>
		<tns:holderType>NIH</tns:holderType>
		<tns:nihInstitution>NEI</tns:nihInstitution>
		<tns:expandedAccess>true</tns:expandedAccess>
		<tns:expandedAccessType>Available</tns:expandedAccessType>
		<tns:exempt>true</tns:exempt>
	</tns:ind>
	<tns:ide>
		<tns:number>222222</tns:number>
		<tns:grantor>CDRH</tns:grantor>
		<tns:holderType>NCI</tns:holderType>
		<tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
		<tns:expandedAccess>true</tns:expandedAccess>
		<tns:expandedAccessType>Available</tns:expandedAccessType>
		<tns:exempt>true</tns:exempt>
	</tns:ide>	
	<tns:protocolDocument filename="protocol.pdf">dGVzdA==</tns:protocolDocument>
	<tns:irbApprovalDocument filename="irb.pdf">dGVzdA==</tns:irbApprovalDocument>
	<tns:participatingSitesDocument
		filename="sites.pdf">dGVzdA==</tns:participatingSitesDocument>
	<tns:informedConsentDocument filename="consent.pdf">dGVzdA==</tns:informedConsentDocument>
	<tns:otherDocument filename="other.pdf">dGVzdA==</tns:otherDocument>
	<tns:category>Externally Peer-Reviewed</tns:category>
	<tns:trialOwner>submitter-ci@example.com</tns:trialOwner>
</tns:CompleteTrialRegistration>

Request (trial with minimum data):

Code Block

language	html/xml
collapse	true

<tns:CompleteTrialRegistration xmlns:tns="gov.nih.nci.pa.webservices.types"
	xmlns:tns1="gov.nih.nci.po.webservices.types.trimmed" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
	xsi:schemaLocation="gov.nih.nci.pa.webservices.types ../../src/resources/ws.xsd ">	

	<tns:leadOrgTrialID>UPCC 34890534</tns:leadOrgTrialID>
	<tns:title>A Phase I/II Study Of Brentuximab Vedotin In Combination With Multi-Agent Chemotherapy</tns:title>
	<tns:phase>I</tns:phase>
	<tns:accrualDiseaseTerminology>ICD10</tns:accrualDiseaseTerminology>
	<tns:primaryPurpose>Treatment</tns:primaryPurpose>
	<tns:interventionalDesign />
	<tns:leadOrganization>
		<tns:existingOrganization>
			<tns:poID>1</tns:poID>
		</tns:existingOrganization>
	</tns:leadOrganization>
	<tns:pi>
		<tns:existingPerson>
			<tns:poID>1</tns:poID>
		</tns:existingPerson>
	</tns:pi>
	<tns:summary4FundingSponsor>
		<tns:existingOrganization>
			<tns:poID>2</tns:poID>
		</tns:existingOrganization>
	</tns:summary4FundingSponsor>
	<tns:fundedByNciGrant>false</tns:fundedByNciGrant>
	<tns:trialStatus>In Review</tns:trialStatus>
	<tns:trialStatusDate>2001-01-01</tns:trialStatusDate>
	<tns:trialStartDate type="Actual">2001-01-01
	</tns:trialStartDate>
	<tns:primaryCompletionDate type="Actual">2001-01-01
	</tns:primaryCompletionDate>
	<tns:protocolDocument filename="protocol.pdf">MA==
	</tns:protocolDocument>
	<tns:irbApprovalDocument filename="irb.pdf">MA==
	</tns:irbApprovalDocument>
	<tns:category>National</tns:category>
	<tns:trialOwner>submitter-ci@example.com</tns:trialOwner>
</tns:CompleteTrialRegistration>

Request (trial where responsible party is Sponsor-Investigator):

Code Block

language	html/xml
collapse	true

<tns:CompleteTrialRegistration xmlns:tns="gov.nih.nci.pa.webservices.types"
	xmlns:tns1="gov.nih.nci.po.webservices.types.trimmed" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
	xsi:schemaLocation="gov.nih.nci.pa.webservices.types ../../src/resources/ws.xsd ">

	<tns:leadOrgTrialID>UPCC 34890534</tns:leadOrgTrialID>
	<tns:clinicalTrialsDotGovTrialID>NCT01994850</tns:clinicalTrialsDotGovTrialID>
	<tns:otherTrialID>818280234</tns:otherTrialID>
	<tns:title>A Phase I/II Study Of Brentuximab Vedotin In Combination With Multi-Agent Chemotherapy</tns:title>
	<tns:phase>I</tns:phase>
	<tns:pilot>false</tns:pilot>
	<tns:accrualDiseaseTerminology>ICD10</tns:accrualDiseaseTerminology>
	<tns:primaryPurpose>Other</tns:primaryPurpose>
	<tns:primaryPurposeOtherDescription>Determine maximum tolerated dose (MTD) of brentuximab vedotin</tns:primaryPurposeOtherDescription>
	<tns:interventionalDesign>
		<tns:secondaryPurpose>Other</tns:secondaryPurpose>
		<tns:secondaryPurposeOtherDescription>Secondary Other Description</tns:secondaryPurposeOtherDescription>
	</tns:interventionalDesign>
	<tns:leadOrganization>
		<tns:existingOrganization>
			<tns:poID>1</tns:poID>
		</tns:existingOrganization>
	</tns:leadOrganization>
	<tns:pi>
		<tns:existingPerson>
			<tns:poID>1</tns:poID>
		</tns:existingPerson>
	</tns:pi>
	<tns:sponsor>
		<tns:existingOrganization>
			<tns:poID>2</tns:poID>
		</tns:existingOrganization>
	</tns:sponsor>
	<tns:responsibleParty>
		<tns:type>Sponsor-Investigator</tns:type>
		<tns:investigator>
		<tns:existingPerson>
			<tns:poID>1</tns:poID>
		</tns:existingPerson>
		</tns:investigator>
		<tns:investigatorTitle>CEO &amp; Chairman</tns:investigatorTitle>
	</tns:responsibleParty>
	<tns:summary4FundingSponsor>
		<tns:existingOrganization>
			<tns:poID>3</tns:poID>
		</tns:existingOrganization>
	</tns:summary4FundingSponsor>
	<tns:programCode>PG00001</tns:programCode>
	<tns:fundedByNciGrant>false</tns:fundedByNciGrant>
	<tns:grant>
		<tns:fundingMechanism>B09</tns:fundingMechanism>
		<tns:nihInstitutionCode>AA</tns:nihInstitutionCode>
		<tns:serialNumber>111111</tns:serialNumber>
		<tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
		<tns:fundingPercentage>100.0</tns:fundingPercentage>
	</tns:grant>
	<tns:trialStatus>In Review</tns:trialStatus>
	<tns:whyStopped></tns:whyStopped>
	<tns:trialStatusDate>2014-07-15</tns:trialStatusDate>
	<tns:trialStartDate type="Actual">2014-07-15</tns:trialStartDate>
	<tns:primaryCompletionDate type="Anticipated">2016-07-15</tns:primaryCompletionDate>
	<tns:completionDate type="Anticipated">2016-07-15</tns:completionDate>
	<tns:ind>
		<tns:number>111111</tns:number>
		<tns:grantor>CDER</tns:grantor>
		<tns:holderType>NIH</tns:holderType>
		<tns:nihInstitution>NEI</tns:nihInstitution>
		<tns:expandedAccess>true</tns:expandedAccess>
		<tns:expandedAccessType>Available</tns:expandedAccessType>
		<tns:exempt>true</tns:exempt>
	</tns:ind>
	<tns:ide>
		<tns:number>222222</tns:number>
		<tns:grantor>CDRH</tns:grantor>
		<tns:holderType>NCI</tns:holderType>
		<tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
		<tns:expandedAccess>true</tns:expandedAccess>
		<tns:expandedAccessType>Available</tns:expandedAccessType>
		<tns:exempt>true</tns:exempt>
	</tns:ide>
	<tns:regulatoryInformation>
		<tns:country>USA</tns:country>
		<tns:authorityName>Federal Government</tns:authorityName>
		<tns:fdaRegulated>true</tns:fdaRegulated>
		<tns:section801>true</tns:section801>
		<tns:delayedPosting>true</tns:delayedPosting>
		<tns:dataMonitoringCommitteeAppointed>true</tns:dataMonitoringCommitteeAppointed>
	</tns:regulatoryInformation>
	<tns:protocolDocument filename="protocol.pdf">dGVzdA==</tns:protocolDocument>
	<tns:irbApprovalDocument filename="irb.pdf">dGVzdA==</tns:irbApprovalDocument>
	<tns:participatingSitesDocument
		filename="sites.pdf">dGVzdA==</tns:participatingSitesDocument>
	<tns:informedConsentDocument filename="consent.pdf">dGVzdA==</tns:informedConsentDocument>
	<tns:otherDocument filename="other.pdf">dGVzdA==</tns:otherDocument>
	<tns:category>Externally Peer-Reviewed</tns:category>
	<tns:trialOwner>submitter-ci@example.com</tns:trialOwner>
</tns:CompleteTrialRegistration>

Response:

Code Block

language	html/xml
collapse	true

<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<TrialRegistrationConfirmation xmlns="gov.nih.nci.pa.webservices.types"
    xmlns:ns2="gov.nih.nci.po.webservices.types.trimmed">
    <paTrialID>137908558</paTrialID>
    <nciTrialID>NCI-2014-00496</nciTrialID>
</TrialRegistrationConfirmation>

...

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