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Tip

title	Use PO Web Services API

We strongly recommended recommend that you exercise PO Web Services API separately in order to find persons and organizations of interest prior to registering a trial. For instructions, refer to Person and Organization Service. Once you find a person or organization, you can use their IDs within a trial registration packet as shown in API examples below. This helps to minimize duplicates in the CTRP system.

...

HTTP Method POST

URL

/trials/abbreviated/{idType}/{trialID}

Parameters

{idType}. Type of identifier you want to use to identify a trial in CTRP. Possible values: pa, nci, ctep.

{trialID}. Trial identifier value itself.

Request Body

XML document with

AbbreviatedTrialUpdate

MIME Type: application/xml

Response Body

XML document with

TrialRegistrationConfirmation

MIME Type: application/xml

HTTP Response Code

200. Success

400. Validation error (including the condition when you are not allowed to update a particular trial)

401. Invalid username/password or insufficient permissions to access the service.

404. One of the Persons/Organizations acting on the trial was not found in PO

500. Internal server error

Examples

URL: https://trials.nci.nih.gov/services/trials/abbreviated/nci/NCI-2014-00496

Request:

Code Block

language	html/xml
collapse	true

<?xml version="1.0" encoding="UTF-8" standalone="yes"?><tns:AbbreviatedTrialUpdate xmlns:tns="gov.nih.nci.pa.webservices.types"
	xmlns:tns1="gov.nih.nci.po.webservices.types.trimmed" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
	xsi:schemaLocation="gov.nih.nci.pa.webservices.types ../../src/resources/ws.xsd ">
	<tns:clinicalTrialsDotGovTrialID>NCT234234234<clinicalTrialsDotGovTrialID>NCT87654321</tns:clinicalTrialsDotGovTrialID>
	<tns:irbApprovalDocument filename="irb_u.pdf">dGVzdA==</tns:irbApprovalDocument>
	<tns:informedConsentDocument filename="consent_u.pdf">dGVzdA==</tns:informedConsentDocument>
	<tns:otherDocument filename="other_u1.pdf">dGVzdA==</tns:otherDocument>	
</tns:AbbreviatedTrialUpdate>

Response:

Code Block

language	html/xml
collapse	true

<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<TrialRegistrationConfirmation xmlns="gov.nih.nci.pa.webservices.types"
    xmlns:ns2="gov.nih.nci.po.webservices.types.trimmed">
    <paTrialID>137908558</paTrialID>
    <nciTrialID>NCI-2014-00496</nciTrialID>
</TrialRegistrationConfirmation>

...

HTTP Method POST

URL /trials/complete

Request Body

XML document with

CompleteTrialRegistration

MIME Type: application/xml

Response Body

XML document with

TrialRegistrationConfirmation

MIME Type: application/xml.

HTTP Response Code

200. Success

400. Validation error

401. Invalid username/password or insufficient permissions to access the service.

404. One of the Persons/Organizations acting on the trial was not found in PO

500. Internal server error

Examples

URL: https://trials.nci.nih.gov/services/trials/complete

Request (referring to existing Organizations and Persons by ID):

Code Block

language	html/xml
collapse	true

<?xml version="1.0" encoding="UTF-8"?>
<tns:CompleteTrialRegistration 
    xmlns:tns="gov.nih.nci.pa.webservices.types"
    xmlns:tns1="gov.nih.nci.po.webservices.types.trimmed" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
    xsi:schemaLocation="gov.nih.nci.pa.webservices.types ../../src/resources/ws.xsd ">

    <tns:clinicalTrialsDotGovXmlRequired>true</tns:clinicalTrialsDotGovXmlRequired>
    <tns:leadOrgTrialID>REST00001</tns:leadOrgTrialID>
    <tns:clinicalTrialsDotGovTrialID>NCT12345678</tns:clinicalTrialsDotGovTrialID>
    <tns:dcpIdentifier>DCP123</tns:dcpIdentifier>
    <tns:otherTrialID>OTHER00000000001</tns:otherTrialID>
    <tns:title>RESTtitle>A Phase I Study of REST Trial Test<Registration</tns:title>
    <tns:phase>I</tns:phase>
    <tns:pilot>false</tns:pilot>
    <tns:accrualDiseaseTerminology>SDC</tns:accrualDiseaseTerminology>
    <tns:primaryPurpose>Other</tns:primaryPurpose>
    <tns:primaryPurposeOtherDescription>PP Other Description<primaryPurposeOtherDescription>Additional description of the trial's purpose</tns:primaryPurposeOtherDescription>
    <tns:interventionalDesign>
        <tns:secondaryPurpose>Other</tns:secondaryPurpose>
        <tns:secondaryPurposeOtherDescription>Secondary Other Descr<secondaryPurposeOtherDescription>Additional description of the trial's purpose</tns:secondaryPurposeOtherDescription>
    </tns:interventionalDesign>
    <tns:leadOrganization>
        <tns:existingOrganization>
            <tns:poID>1</tns:poID>
        </tns:existingOrganization>
    </tns:leadOrganization>
    <tns:pi>
        <tns:existingPerson>
            <tns:poID>1</tns:poID>
        </tns:existingPerson>
    </tns:pi>
    <tns:sponsor>
        <tns:existingOrganization>
            <tns:poID>2</tns:poID>
        </tns:existingOrganization>
    </tns:sponsor>
    <tns:responsibleParty>
        <tns:type>Sponsor</tns:type>
    </tns:responsibleParty>
    <tns:summary4FundingSponsor>
        <tns:existingOrganization>
            <tns:poID>3</tns:poID>
        </tns:existingOrganization>
    </tns:summary4FundingSponsor>
    <tns:programCode>REST_PG01<programCode>PG00001</tns:programCode>
    <tns:fundedByNciGrant>false</tns:fundedByNciGrant>
    <tns:grant>
        <tns:fundingMechanism>B01</tns:fundingMechanism>
        <tns:nihInstitutionCode>AA</tns:nihInstitutionCode>
        <tns:serialNumber>111111</tns:serialNumber>
        <tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
        <tns:fundingPercentage>100.0</tns:fundingPercentage>
    </tns:grant>
    <tns:trialStatus>In Review</tns:trialStatus>
    <tns:whyStopped>If study stopped, enter the reason why.</tns:whyStopped>
    <tns:trialStatusDate>2014-07-15</tns:trialStatusDate>
    <tns:trialStartDate type="Actual">2014-07-15</tns:trialStartDate>
    <tns:primaryCompletionDate type="Anticipated">2018-07-15</tns:primaryCompletionDate>
    <tns:completionDate type="Anticipated">2018-07-15</tns:completionDate>
    <tns:ind>
        <tns:number>111111</tns:number>
        <tns:grantor>CDER</tns:grantor>
        <tns:holderType>NIH</tns:holderType>
        <tns:nihInstitution>NEI</tns:nihInstitution>
        <tns:expandedAccess>true</tns:expandedAccess>
        <tns:expandedAccessRecord>NCT12345688</tns:expandedAccessRecord>
        <tns:expandedAccessType>Available</tns:expandedAccessType>
        <tns:exempt>true</tns:exempt>
    </tns:ind>
    <tns:ide>
        <tns:number>222222</tns:number>
        <tns:grantor>CDRH</tns:grantor>
        <tns:holderType>NCI</tns:holderType>
        <tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
        <tns:expandedAccess>true</tns:expandedAccess>
        <tns:expandedAccessRecord>NCT12345688</tns:expandedAccessRecord>
        <tns:expandedAccessType>Available</tns:expandedAccessType>
        <tns:exempt>true</tns:exempt>
    </tns:ide>
    <tns:regulatoryInformation>
        <tns:country>USA</tns:country>
        <tns:authorityName>Federal Government</tns:authorityName>
        <tns:fdaRegulatedDrug>true</tns:fdaRegulatedDrug>
        <tns:fdaRegulatedDevice>true</tns:fdaRegulatedDevice>
        <tns:approvalClearance>false</tns:approvalClearance>
        <tns:marketSurveillance>true</tns:marketSurveillance>
        <tns:usaExport>true</tns:usaExport>
        <tns:fdaRegulated>true</tns:fdaRegulated>
        <tns:section801>true</tns:section801>
        <tns:delayedPosting>false</tns:delayedPosting>
        <tns:dataMonitoringCommitteeAppointed>true</tns:dataMonitoringCommitteeAppointed>
    </tns:regulatoryInformation>
    <tns:protocolDocument filename="protocol.pdf">dGVzdA==</tns:protocolDocument>
    <tns:irbApprovalDocument filename="irb.pdf">dGVzdA==</tns:irbApprovalDocument>
    <tns:participatingSitesDocument
            filename="sites.pdf">dGVzdA==</tns:participatingSitesDocument>
    <tns:informedConsentDocument filename="consent.pdf">dGVzdA==</tns:informedConsentDocument>
    <tns:otherDocument filename="other.pdf">dGVzdA==</tns:otherDocument>
    <tns:category>Externally Peer-Reviewed</tns:category>
    <tns:trialOwner>submitter-ci@example.com</tns:trialOwner>
</tns:CompleteTrialRegistration>

Request (non-interventional trial):

Code Block

language	html/xml
collapse	true

<tns:CompleteTrialRegistration xmlns:tns="gov.nih.nci.pa.webservices.types"
	xmlns:tns1="gov.nih.nci.po.webservices.types.trimmed" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
	xsi:schemaLocation="gov.nih.nci.pa.webservices.types ../../src/resources/ws.xsd ">
	
    <tns:clinicalTrialsDotGovXmlRequired>true</tns:clinicalTrialsDotGovXmlRequired>
	<tns:leadOrgTrialID>UPCC 34890534<leadOrgTrialID>REST00001</tns:leadOrgTrialID>
	<tns:clinicalTrialsDotGovTrialID>NCT01994850<clinicalTrialsDotGovTrialID>NCT01234567</tns:clinicalTrialsDotGovTrialID>
	<tns:otherTrialID>818280234<otherTrialID>OTHER00000000002</tns:otherTrialID>
	<tns:title>A Phase I/II Study Ofof BrentuximabREST Vedotin In Combination With Multi-Agent Chemotherapy<Trial Registration</tns:title>
	<tns:phase>I</tns:phase>
	<tns:pilot>false</tns:pilot>
	<tns:accrualDiseaseTerminology>ICD10</tns:accrualDiseaseTerminology>
	<tns:primaryPurpose>Other</tns:primaryPurpose>
	<tns:primaryPurposeOtherDescription>DetermineprimaryPurposeOtherDescription>Additional maximumdescription toleratedof dose (MTD) of brentuximab vedotin<the trial's purpose</tns:primaryPurposeOtherDescription>
	<tns:nonInterventionalDesign>
		<tns:trialType>Observational</tns:trialType>
		<tns:studyModelCode>Other</tns:studyModelCode>
		<tns:studyModelCodeOtherDescription>studyModelCode other</tns:studyModelCodeOtherDescription>
		<tns:timePerspectiveCode>Other</tns:timePerspectiveCode>
		<tns:timePerspectiveCodeOtherDescription>timePerspectiveCode other</tns:timePerspectiveCodeOtherDescription>
	</tns:nonInterventionalDesign>
	<tns:leadOrganization>
		<tns:existingOrganization>
			<tns:poID>1</tns:poID>
		</tns:existingOrganization>
	</tns:leadOrganization>
	<tns:pi>
		<tns:existingPerson>
			<tns:poID>1</tns:poID>
		</tns:existingPerson>
	</tns:pi>
	<tns:sponsor>
		<tns:existingOrganization>
			<tns:poID>2</tns:poID>
		</tns:existingOrganization>
	</tns:sponsor>
	<tns:responsibleParty>
		<tns:type>Sponsor</tns:type>
	</tns:responsibleParty>
	<tns:summary4FundingSponsor>
		<tns:existingOrganization>
			<tns:poID>3</tns:poID>
		</tns:existingOrganization>
	</tns:summary4FundingSponsor>
	<tns:programCode>PG00001</tns:programCode>
	<tns:fundedByNciGrant>false</tns:fundedByNciGrant>
	<tns:grant>
		<tns:fundingMechanism>B09</tns:fundingMechanism>
		<tns:nihInstitutionCode>AA</tns:nihInstitutionCode>
		<tns:serialNumber>111111</tns:serialNumber>
		<tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
		<tns:fundingPercentage>100.0</tns:fundingPercentage>
	</tns:grant>
	<tns:trialStatus>In Review</tns:trialStatus>
	<tns:whyStopped><whyStopped>If study stopped, enter the reason why.</tns:whyStopped>
	<tns:trialStatusDate>2014-07-15</tns:trialStatusDate>
	<tns:trialStartDate type="Actual">2014-07-15</tns:trialStartDate>
	<tns:primaryCompletionDate type="Anticipated">2016>2018-07-15</tns:primaryCompletionDate>
	<tns:completionDate type="Anticipated">2016>2018-07-15</tns:completionDate>
	<tns:ind>
		<tns:number>111111</tns:number>
		<tns:grantor>CDER</tns:grantor>
		<tns:holderType>NIH</tns:holderType>
		<tns:nihInstitution>NEI</tns:nihInstitution>
		<tns:expandedAccess>true</tns:expandedAccess>
        <tns:expandedAccessRecord>NCT12345688</tns:expandedAccessRecord>
		<tns:expandedAccessType>Available</tns:expandedAccessType>
		<tns:exempt>true</tns:exempt>
	</tns:ind>
	<tns:ide>
		<tns:number>222222</tns:number>
		<tns:grantor>CDRH</tns:grantor>
		<tns:holderType>NCI</tns:holderType>
		<tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
		<tns:expandedAccess>true</tns:expandedAccess>
        <tns:expandedAccessRecord>NCT12345688</tns:expandedAccessRecord>
		<tns:expandedAccessType>Available</tns:expandedAccessType>
		<tns:exempt>true</tns:exempt>
	</tns:ide>
	<tns:regulatoryInformation>
		<tns:country>USA</tns:country>
		<tns:authorityName>Federal Government</tns:authorityName>
		        <tns:fdaRegulated>true<fdaRegulatedDrug>true</tns:fdaRegulated>
		fdaRegulatedDrug>
        <tns:section801>true<fdaRegulatedDevice>true</tns:section801>
		fdaRegulatedDevice>
        <tns:delayedPosting>true<approvalClearance>false</tns:delayedPosting>
		<tns:approvalClearance>
        <tns:marketSurveillance>true</tns:marketSurveillance>
        <tns:usaExport>true</tns:usaExport>
		<tns:fdaRegulated>true</tns:fdaRegulated>
		<tns:section801>true</tns:section801>
		<tns:delayedPosting>false</tns:delayedPosting>
		<tns:dataMonitoringCommitteeAppointed>true</tns:dataMonitoringCommitteeAppointed>
	</tns:regulatoryInformation>
	<tns:protocolDocument filename="protocol.pdf">dGVzdA==</tns:protocolDocument>
	<tns:irbApprovalDocument filename="irb.pdf">dGVzdA==</tns:irbApprovalDocument>
	<tns:participatingSitesDocument
		filename="sites.pdf">dGVzdA==</tns:participatingSitesDocument>
	<tns:informedConsentDocument filename="consent.pdf">dGVzdA==</tns:informedConsentDocument>
	<tns:otherDocument filename="other.pdf">dGVzdA==</tns:otherDocument>
	<tns:category>Externally Peer-Reviewed</tns:category>
	<tns:trialOwner>submitter-ci@example.com</tns:trialOwner>
</tns:CompleteTrialRegistration>

Request (trial where submission to ClinicalTrials.gov is not required):

Code Block

language	html/xml
collapse	true

<tns:CompleteTrialRegistration xmlns:tns="gov.nih.nci.pa.webservices.types"
	xmlns:tns1="gov.nih.nci.po.webservices.types.trimmed" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
	xsi:schemaLocation="gov.nih.nci.pa.webservices.types ../../src/resources/ws.xsd ">	

    <tns:clinicalTrialsDotGovXmlRequired>false</tns:clinicalTrialsDotGovXmlRequired>
	<tns:leadOrgTrialID>UPCC 34890534<leadOrgTrialID>REST00001</tns:leadOrgTrialID>
	<tns:clinicalTrialsDotGovTrialID>NCT01994850<clinicalTrialsDotGovTrialID>NCT12345678</tns:clinicalTrialsDotGovTrialID>
	<tns:otherTrialID>818280234<otherTrialID>OTHER00000000001</tns:otherTrialID>
	<tns:title>A Phase I/II Study Ofof BrentuximabREST Vedotin In Combination With Multi-Agent Chemotherapy<Trial Registration</tns:title>
	<tns:phase>I</tns:phase>
	<tns:pilot>false</tns:pilot>
	<tns:accrualDiseaseTerminology>ICD10</tns:accrualDiseaseTerminology>
	<tns:primaryPurpose>Other</tns:primaryPurpose>
	<tns:primaryPurposeOtherDescription>DetermineprimaryPurposeOtherDescription>Additional maximumdescription toleratedof dose (MTD) of brentuximab vedotin<the trial's purpose</tns:primaryPurposeOtherDescription>
	<tns:interventionalDesign>
		<tns:secondaryPurpose>Other</tns:secondaryPurpose>
		<tns:secondaryPurposeOtherDescription>Secondary Other Description<secondaryPurposeOtherDescription>Additional description of the trial's purpose</tns:secondaryPurposeOtherDescription>
	</tns:interventionalDesign>
	<tns:leadOrganization>
		<tns:existingOrganization>
			<tns:poID>1</tns:poID>
		</tns:existingOrganization>
	</tns:leadOrganization>
	<tns:pi>
		<tns:existingPerson>
			<tns:poID>1</tns:poID>
		</tns:existingPerson>
	</tns:pi>	
	<tns:summary4FundingSponsor>
		<tns:existingOrganization>
			<tns:poID>3</tns:poID>
		</tns:existingOrganization>
	</tns:summary4FundingSponsor>
	<tns:programCode>PG00001</tns:programCode>
	<tns:fundedByNciGrant>false</tns:fundedByNciGrant>
	<tns:grant>
		<tns:fundingMechanism>B09</tns:fundingMechanism>
		<tns:nihInstitutionCode>AA</tns:nihInstitutionCode>
		<tns:serialNumber>111111</tns:serialNumber>
		<tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
		<tns:fundingPercentage>100.0</tns:fundingPercentage>
	</tns:grant>
	<tns:trialStatus>In Review</tns:trialStatus>
	<tns:whyStopped><whyStopped>If study stopped, enter the reason why.</tns:whyStopped>
	<tns:trialStatusDate>2014-07-15</tns:trialStatusDate>
	<tns:trialStartDate type="Actual">2014-07-15</tns:trialStartDate>
	<tns:primaryCompletionDate type="Anticipated">2016>2018-07-15</tns:primaryCompletionDate>
	<tns:completionDate type="Anticipated">2016>2018-07-15</tns:completionDate>
	<tns:ind>
		<tns:number>111111</tns:number>
		<tns:grantor>CDER</tns:grantor>
		<tns:holderType>NIH</tns:holderType>
		<tns:nihInstitution>NEI</tns:nihInstitution>
		<tns:expandedAccess>true</tns:expandedAccess>
        <tns:expandedAccessRecord>NCT12345688</tns:expandedAccessRecord>
		<tns:expandedAccessType>Available</tns:expandedAccessType>
		<tns:exempt>true</tns:exempt>
	</tns:ind>
	<tns:ide>
		<tns:number>222222</tns:number>
		<tns:grantor>CDRH</tns:grantor>
		<tns:holderType>NCI</tns:holderType>
		<tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
		<tns:expandedAccess>true</tns:expandedAccess>
        <tns:expandedAccessRecord>NCT12345688</tns:expandedAccessRecord>
		<tns:expandedAccessType>Available</tns:expandedAccessType>
		<tns:exempt>true</tns:exempt>
	</tns:ide>	
	<tns:protocolDocument filename="protocol.pdf">dGVzdA==</tns:protocolDocument>
	<tns:irbApprovalDocument filename="irb.pdf">dGVzdA==</tns:irbApprovalDocument>
	<tns:participatingSitesDocument
		filename="sites.pdf">dGVzdA==</tns:participatingSitesDocument>
	<tns:informedConsentDocument filename="consent.pdf">dGVzdA==</tns:informedConsentDocument>
	<tns:otherDocument filename="other.pdf">dGVzdA==</tns:otherDocument>
	<tns:category>Externally Peer-Reviewed</tns:category>
	<tns:trialOwner>submitter-ci@example.com</tns:trialOwner>
</tns:CompleteTrialRegistration>

Request (trial with minimum data):

Code Block

language	html/xml
collapse	true

<tns:CompleteTrialRegistration xmlns:tns="gov.nih.nci.pa.webservices.types"
	xmlns:tns1="gov.nih.nci.po.webservices.types.trimmed" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
	xsi:schemaLocation="gov.nih.nci.pa.webservices.types ../../src/resources/ws.xsd ">	

    <tns:clinicalTrialsDotGovXmlRequired>false</tns:clinicalTrialsDotGovXmlRequired>
	<tns:leadOrgTrialID>UPCC 34890534<leadOrgTrialID>REST00001</tns:leadOrgTrialID>
	<tns:title>A Phase I/II Study Ofof BrentuximabREST Vedotin In Combination With Multi-Agent Chemotherapy</tns:Trial Registration</tns:title>
	<tns:phase>I</tns:phase>
	<tns:accrualDiseaseTerminology>ICD10</tns:accrualDiseaseTerminology>
	<tns:primaryPurpose>Treatment</tns:primaryPurpose>
	<tns:interventionalDesign />
	<tns:leadOrganization>
		<tns:existingOrganization>
			<tns:poID>1</tns:poID>
		</tns:existingOrganization>
	</tns:leadOrganization>
	<tns:pi>
		<tns:existingPerson>
			<tns:poID>1</tns:poID>
		</tns:existingPerson>
	</tns:pi>
	<tns:summary4FundingSponsor>
		<tns:existingOrganization>
			<tns:poID>2</tns:poID>
		</tns:existingOrganization>
	</tns:summary4FundingSponsor>
	<tns:fundedByNciGrant>false</tns:fundedByNciGrant>
	<tns:trialStatus>In Review</tns:trialStatus>
	<tns:trialStatusDate>2001-01-01</tns:trialStatusDate>
	<tns:trialStartDate type="Actual">2001-01-01
	</tns:trialStartDate>
	<tns:primaryCompletionDate type="Actual">2001-01-01
	</tns:primaryCompletionDate>
	<tns:protocolDocument filename="protocol.pdf">MA==
	</tns:protocolDocument>
	<tns:irbApprovalDocument filename="irb.pdf">MA==
	</tns:irbApprovalDocument>
	<tns:category>National</tns:category>
	<tns:trialOwner>submitter-ci@example.com</tns:trialOwner>
</tns:CompleteTrialRegistration>

Request (trial where responsible party is Sponsor-Investigator):

Code Block

language	html/xml
collapse	true

<tns:CompleteTrialRegistration xmlns:tns="gov.nih.nci.pa.webservices.types"
	xmlns:tns1="gov.nih.nci.po.webservices.types.trimmed" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
	xsi:schemaLocation="gov.nih.nci.pa.webservices.types ../../src/resources/ws.xsd ">

    <tns:clinicalTrialsDotGovXmlRequired>true</tns:clinicalTrialsDotGovXmlRequired>
	<tns:leadOrgTrialID>UPCC 34890534<leadOrgTrialID>REST00001</tns:leadOrgTrialID>
	<tns:clinicalTrialsDotGovTrialID>NCT01994850<clinicalTrialsDotGovTrialID>NCT12345678</tns:clinicalTrialsDotGovTrialID>
	<tns:otherTrialID>818280234<otherTrialID>OTHER00000000001</tns:otherTrialID>
	<tns:title>A Phase I/II Study Ofof BrentuximabREST Vedotin In Combination With Multi-Agent Chemotherapy<Trial Registration</tns:title>
	<tns:phase>I</tns:phase>
	<tns:pilot>false</tns:pilot>
	<tns:accrualDiseaseTerminology>ICD10</tns:accrualDiseaseTerminology>
	<tns:primaryPurpose>Other</tns:primaryPurpose>
	<tns:primaryPurposeOtherDescription>DetermineprimaryPurposeOtherDescription>Additional maximumdescription toleratedof dose (MTD) of brentuximab vedotin<the trial's purpose</tns:primaryPurposeOtherDescription>
	<tns:interventionalDesign>
		<tns:secondaryPurpose>Other</tns:secondaryPurpose>
		<tns:secondaryPurposeOtherDescription>Secondary Other Description<secondaryPurposeOtherDescription>Additional description of the trial's purpose</tns:secondaryPurposeOtherDescription>
	</tns:interventionalDesign>
	<tns:leadOrganization>
		<tns:existingOrganization>
			<tns:poID>1</tns:poID>
		</tns:existingOrganization>
	</tns:leadOrganization>
	<tns:pi>
		<tns:existingPerson>
			<tns:poID>1</tns:poID>
		</tns:existingPerson>
	</tns:pi>
	<tns:sponsor>
		<tns:existingOrganization>
			<tns:poID>2</tns:poID>
		</tns:existingOrganization>
	</tns:sponsor>
	<tns:responsibleParty>
		<tns:type>Sponsor-Investigator</tns:type>
		<tns:investigator>
		<tns:existingPerson>
			<tns:poID>1</tns:poID>
		</tns:existingPerson>
		</tns:investigator>
		<tns:investigatorTitle>CEO &amp; Chairman</tns:investigatorTitle>
	</tns:responsibleParty>
	<tns:summary4FundingSponsor>
		<tns:existingOrganization>
			<tns:poID>3</tns:poID>
		</tns:existingOrganization>
	</tns:summary4FundingSponsor>
	<tns:programCode>PG00001</tns:programCode>
	<tns:fundedByNciGrant>false</tns:fundedByNciGrant>
	<tns:grant>
		<tns:fundingMechanism>B09</tns:fundingMechanism>
		<tns:nihInstitutionCode>AA</tns:nihInstitutionCode>
		<tns:serialNumber>111111</tns:serialNumber>
		<tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
		<tns:fundingPercentage>100.0</tns:fundingPercentage>
	</tns:grant>
	<tns:trialStatus>In Review</tns:trialStatus>
	<tns:whyStopped><whyStopped>If study stopped, enter the reason why.</tns:whyStopped>
	<tns:trialStatusDate>2014-07-15</tns:trialStatusDate>
	<tns:trialStartDate type="Actual">2014-07-15</tns:trialStartDate>
	<tns:primaryCompletionDate type="Anticipated">2016>2018-07-15</tns:primaryCompletionDate>
	<tns:completionDate type="Anticipated">2016>2018-07-15</tns:completionDate>
	<tns:ind>
		<tns:number>111111</tns:number>
		<tns:grantor>CDER</tns:grantor>
		<tns:holderType>NIH</tns:holderType>
		<tns:nihInstitution>NEI</tns:nihInstitution>
		<tns:expandedAccess>true</tns:expandedAccess>
		        <tns:expandedAccessRecord>NCT12345688</tns:expandedAccessRecord>
		<tns:expandedAccessType>Available</tns:expandedAccessType>
		<tns:exempt>true</tns:exempt>
	</tns:ind>
	<tns:ide>
		<tns:number>222222</tns:number>
		<tns:grantor>CDRH</tns:grantor>
		<tns:holderType>NCI</tns:holderType>
		<tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
		<tns:expandedAccess>true</tns:expandedAccess>
        <tns:expandedAccessRecord>NCT12345688</tns:expandedAccessRecord>
		<tns:expandedAccessType>Available</tns:expandedAccessType>
		<tns:exempt>true</tns:exempt>
	</tns:ide>
	<tns:regulatoryInformation>
		<tns:country>USA</tns:country>
		<tns:authorityName>Federal Government</tns:authorityName> Government</tns:authorityName>
        <tns:fdaRegulatedDrug>true</tns:fdaRegulatedDrug>
        <tns:fdaRegulatedDevice>true</tns:fdaRegulatedDevice>
        <tns:approvalClearance>false</tns:approvalClearance>
        <tns:marketSurveillance>true</tns:marketSurveillance>
        <tns:usaExport>true</tns:usaExport>
		<tns:fdaRegulated>true</tns:fdaRegulated>
		<tns:section801>true</tns:section801>
		<tns:delayedPosting>true<delayedPosting>false</tns:delayedPosting>
		<tns:dataMonitoringCommitteeAppointed>true</tns:dataMonitoringCommitteeAppointed>
	</tns:regulatoryInformation>
	<tns:protocolDocument filename="protocol.pdf">dGVzdA==</tns:protocolDocument>
	<tns:irbApprovalDocument filename="irb.pdf">dGVzdA==</tns:irbApprovalDocument>
	<tns:participatingSitesDocument
		filename="sites.pdf">dGVzdA==</tns:participatingSitesDocument>
	<tns:informedConsentDocument filename="consent.pdf">dGVzdA==</tns:informedConsentDocument>
	<tns:otherDocument filename="other.pdf">dGVzdA==</tns:otherDocument>
	<tns:category>Externally Peer-Reviewed</tns:category>
	<tns:trialOwner>submitter-ci@example.com</tns:trialOwner>
</tns:CompleteTrialRegistration>

Response:

Code Block

language	html/xml
collapse	true

<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<TrialRegistrationConfirmation xmlns="gov.nih.nci.pa.webservices.types"
    xmlns:ns2="gov.nih.nci.po.webservices.types.trimmed">
    <paTrialID>137908558</paTrialID>
    <nciTrialID>NCI-2014-00496</nciTrialID>
</TrialRegistrationConfirmation>

...

HTTP Method POST

URL

/trials/complete/{idType}/{trialID}

Parameters

{idType}. Type of identifier you want to use to identify a trial in CTRP. Possible values: pa, nci, ctep, dcp.

{trialID}. Trial identifier value itself.

Request Body

XML document with

CompleteTrialUpdate

MIME Type: application/xml

Response Body

XML document with

TrialRegistrationConfirmation

MIME Type: application/xml

HTTP Response Code

200. Success

400. Validation error (including the condition when you are not allowed to update a particular trial)

401. Invalid username/password or insufficient permissions to access the service.

500. Internal server error

Examples

URL: https://trials.nci.nih.gov/services/trials/complete/nci/NCI-2014-00496

Request:

Code Block

language	html/xml
collapse	true

<tns:CompleteTrialUpdate xmlns:tns="gov.nih.nci.pa.webservices.types"
    xmlns:tns1="gov.nih.nci.po.webservices.types.trimmed" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
    xsi:schemaLocation="gov.nih.nci.pa.webservices.types ../../src/resources/ws.xsd ">    
    <tns:clinicalTrialsDotGovTrialID>NCT11111111111<clinicalTrialsDotGovTrialID>NCT12345678</tns:clinicalTrialsDotGovTrialID>
    <tns:otherTrialID>ADDED01<otherTrialID>OTHER00000000001</tns:otherTrialID>    
    <tns:accrualDiseaseTerminology>ICD-O-3</tns:accrualDiseaseTerminology>
    <tns:grant>
        <tns:fundingMechanism>C06</tns:fundingMechanism>
        <tns:nihInstitutionCode>AA</tns:nihInstitutionCode>
        <tns:serialNumber>111111</tns:serialNumber>
        <tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
        <tns:fundingPercentage>100.0</tns:fundingPercentage>
    </tns:grant>
    <tns:trialStatus>Approved</tns:trialStatus>
    <tns:whyStopped><whyStopped>If study stopped, enter the reason why.</tns:whyStopped>
    <tns:trialStatusDate>2014-07-07</tns:trialStatusDate>
    <tns:trialStartDate type="Actual">2010-01-11</tns:trialStartDate>
    <tns:primaryCompletionDate type="Anticipated">2025-01-01</tns:primaryCompletionDate>
    <tns:completionDate type="Anticipated">2050-01-01</tns:completionDate>
    <tns:protocolDocument filename="protocol_updated.pdf">dGVzdA==</tns:protocolDocument>
    <tns:irbApprovalDocument filename="irb_updated.pdf">dGVzdA==</tns:irbApprovalDocument>
    <tns:participatingSitesDocument
        filename="sites_updated.pdf">dGVzdA==</tns:participatingSitesDocument>
    <tns:informedConsentDocument filename="consent_updated.pdf">dGVzdA==</tns:informedConsentDocument>
    <tns:otherDocument filename="other_updated.pdf">dGVzdA==</tns:otherDocument>
</tns:CompleteTrialUpdate>

Response:

Code Block

language	html/xml
collapse	true

<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<TrialRegistrationConfirmation xmlns="gov.nih.nci.pa.webservices.types"
    xmlns:ns2="gov.nih.nci.po.webservices.types.trimmed">
    <paTrialID>137908558</paTrialID>
    <nciTrialID>NCI-2014-00496</nciTrialID>
</TrialRegistrationConfirmation>

...

HTTP Method PUT

URL

/trials/complete/{idType}/{trialID}

Parameters

{idType}. Type of identifier you want to use to identify a trial in CTRP. Possible values: pa, nci, ctep, dcp.

{trialID}. Trial identifier value itself.

Request Body

XML document with

CompleteTrialAmendment

MIME Type: application/xml

Response Body

XML document with

TrialRegistrationConfirmation

MIME Type: application/xml

HTTP Response Code

200. Success

400. Validation error (including the condition when you are not allowed to amend a particular trial)

401. Invalid username/password or insufficient permissions to access the service.

404. One of the Persons/Organizations acting on the trial was not found in PO

500. Internal server error

Examples

URL: https://trials.nci.nih.gov/services/trials/complete/nci/NCI-2014-00496

Request:

Code Block

language	html/xml
collapse	true

<tns:CompleteTrialAmendment xmlns:tns="gov.nih.nci.pa.webservices.types"
    xmlns:tns1="gov.nih.nci.po.webservices.types.trimmed" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
    xsi:schemaLocation="gov.nih.nci.pa.webservices.types ../../src/resources/ws.xsd ">
    
    <tns:clinicalTrialsDotGovXmlRequired>true</tns:clinicalTrialsDotGovXmlRequired>
    <tns:leadOrgTrialID>UPCC 34890534<leadOrgTrialID>REST00001</tns:leadOrgTrialID>
    <tns:clinicalTrialsDotGovTrialID>NCT34905834785<clinicalTrialsDotGovTrialID>NCT12345678</tns:clinicalTrialsDotGovTrialID>
    <tns:otherTrialID>934875<otherTrialID>OTHER00000000001</tns:otherTrialID>
    <tns:otherTrialID>CCR492384<otherTrialID>OTHER00000000003</tns:otherTrialID>
    <tns:title>A Phase I/IINA Study Ofof BrentuximabREST Vedotin In Combination With Multi-Agent Chemotherapy Amended<Trial Amendment</tns:title>
    <tns:phase>NA</tns:phase>
    <tns:pilot>true</tns:pilot>
    <tns:accrualDiseaseTerminology>ICD-O-3</tns:accrualDiseaseTerminology>
    <tns:primaryPurpose>Basic Science</tns:primaryPurpose>
    <tns:interventionalDesign>
        <tns:secondaryPurpose>Ancillary-Correlative</tns:secondaryPurpose>
    </tns:interventionalDesign>
    <tns:leadOrganization>
		<tns:existingOrganization>
			<tns:poID>1</tns:poID>
		</tns:existingOrganization>
    </tns:leadOrganization>
    <tns:pi>
		<tns:existingPerson>
			<tns:poID>1</tns:poID>
		</tns:existingPerson>
    </tns:pi>
    <tns:sponsor>
		<tns:existingOrganization>
			<tns:poID>2</tns:poID>
		</tns:existingOrganization>
    </tns:sponsor>
    <tns:responsibleParty>
        <tns:type>Sponsor</tns:type>
    </tns:responsibleParty>
    <tns:summary4FundingSponsor>
		<tns:existingOrganization>
			<tns:poID>3</tns:poID>
		</tns:existingOrganization>
    </tns:summary4FundingSponsor>
    <tns:programCode>PG00002</tns:programCode>
    <tns:fundedByNciGrant>false</tns:fundedByNciGrant>
    <tns:grant>
        <tns:fundingMechanism>C06</tns:fundingMechanism>
        <tns:nihInstitutionCode>AG</tns:nihInstitutionCode>
        <tns:serialNumber>343435</tns:serialNumber>
        <tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
        <tns:fundingPercentage>100.0</tns:fundingPercentage>
    </tns:grant>
    <tns:trialStatus>In Review</tns:trialStatus>
    <tns:whyStopped><whyStopped>If study stopped, enter the reason why.</tns:whyStopped>
    <tns:trialStatusDate>2014-07-15</tns:trialStatusDate>
    <tns:trialStartDate type="Actual">2014-07-15</tns:trialStartDate>
    <tns:primaryCompletionDate type="Anticipated">2016>2018-07-15</tns:primaryCompletionDate>
    <tns:completionDate type="Anticipated">2016>2018-07-15</tns:completionDate>
    <tns:ind>
        <tns:number>54554</tns:number>
        <tns:grantor>CDER</tns:grantor>
        <tns:holderType>NIH</tns:holderType>
        <tns:nihInstitution>NEI</tns:nihInstitution>
        <tns:expandedAccess>true</tns:expandedAccess>
        <tns:expandedAccessRecord>NCT12345688</tns:expandedAccessRecord>
        <tns:expandedAccessType>Available</tns:expandedAccessType>
        <tns:exempt>true</tns:exempt>
    </tns:ind>
    <tns:ide>
        <tns:number>646456</tns:number>
        <tns:grantor>CDRH</tns:grantor>
        <tns:holderType>NCI</tns:holderType>
        <tns:nciDivisionProgramCode>CCR</tns:nciDivisionProgramCode>
        <tns:expandedAccess>true</tns:expandedAccess>
        <tns:expandedAccessRecord>NCT12345688</tns:expandedAccessRecord>
        <tns:expandedAccessType>Available</tns:expandedAccessType>
        <tns:exempt>true</tns:exempt>
    </tns:ide>
    <tns:regulatoryInformation>
        <tns:country>USA</tns:country>
        <tns:authorityName>Food and Drug Administration</tns:authorityName>
        <tns:fdaRegulatedDrug>true</tns:fdaRegulatedDrug>
        <tns:fdaRegulatedDevice>true</tns:fdaRegulatedDevice>
        <tns:approvalClearance>false</tns:approvalClearance>
        <tns:marketSurveillance>true</tns:marketSurveillance>
        <tns:usaExport>true</tns:usaExport>
        <tns:fdaRegulated>true</tns:fdaRegulated>
        <tns:section801>true</tns:section801>
        <tns:delayedPosting>true<delayedPosting>false</tns:delayedPosting>
        <tns:dataMonitoringCommitteeAppointed>false</tns:dataMonitoringCommitteeAppointed>
    </tns:regulatoryInformation>
    <tns:protocolDocument filename="protocol_amend.pdf">dGVzdA==</tns:protocolDocument>
    <tns:irbApprovalDocument filename="irb_amend.pdf">dGVzdA==</tns:irbApprovalDocument>
    <tns:participatingSitesDocument
        filename="sites_amend.pdf">dGVzdA==</tns:participatingSitesDocument>
    <tns:informedConsentDocument filename="consent_amend.pdf">dGVzdA==</tns:informedConsentDocument>
    <tns:otherDocument filename="other_amend.pdf">dGVzdA==</tns:otherDocument>
    <tns:amendmentNumber>99</tns:amendmentNumber>
    <tns:amendmentDate>2014-08-01</tns:amendmentDate>
    <tns:ctepIdentifier>CTEP99999999999999</tns:ctepIdentifier>
    <tns:dcpIdentifier>DCP9999999999999999</tns:dcpIdentifier>
    <tns:changeMemoDocument filename="memo.pdf">dGVzdA==</tns:changeMemoDocument>
    <tns:protocolHighlightDocument filename="high.pdf">dGVzdA==</tns:protocolHighlightDocument>
</tns:CompleteTrialAmendment>

Response:

Code Block

language	html/xml
collapse	true

<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<TrialRegistrationConfirmation xmlns="gov.nih.nci.pa.webservices.types"
    xmlns:ns2="gov.nih.nci.po.webservices.types.trimmed">
    <paTrialID>137908558</paTrialID>
    <nciTrialID>NCI-2014-00496</nciTrialID>
</TrialRegistrationConfirmation>

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