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FNLCR supports the Center for Strategic Scientific Initiatives (CSSI), an innovations center within NCI, by managing science and technology initiatives to support development programs critical to nearly all cancer and biomedical research programs in new higher risk areas, including data management, high definition single cell analysis, immuno-mass cytometry, clinical proteomics, and antibody characterization that may question existing paradigms and lead to hypothesis testing. A knowledgeable team of software developers in DSITP, led by Uma Mudunuri and managed by Andrew Quong, have developed the CSSI DCC Portal, a repository for CSSI DCC data and also emerging data types without a standard approach to data storage. The data currently in the DCC conform to the standard Investigation-Study-Assay tab-delimited format (ISA-TAB) format, which describes a scientific investigation, its study or studies, and each study's assay(s).

The primary goals goal of the FNLCR CSSI Data Coordination Center (DCC) are is to facilitate access to research data for the greater cancer research community.   Facilitating this is the DCC's design approach, which follows FAIR (Findable, Accessible, Interoperable, and Reusable) principles for scientific data management and stewardship, applied metadata standards, and involved interactions with the research community to seek out and apply their best practices.

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 The CSSI DCC Portal project team includes: