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IndexersVocabularies may be indexed to provide enhanced performance or query capabilities. Types of indexes incorporated into the LexBIG system include but are not limited to the following:
- Lexical Match - for example, "begins-with" and "contains"
- Phonetic - allows for the ability to query based on "sounds-like" entry of search criteria.
- Stemming - allows for the ability to find lexical variations of search terms.
  Index creation is typically bundled into the load process. Architecturally speaking, however, this capability is decoupled and extensible.
- Asserted Value Set Indexing – Indexes value sets separately from the source terminology
Loaders
Vocabularies may be imported to the system from a variety of accepted formats, including but not limited to:
- LexGrid XML (LexBIG canonical format)
- NCI Thesaurus, provided in Web Ontology Language format (OWL)
- UMLS Rich Release format (RRF)
- Open Biomedical Ontologies format (OBO)
  As with indexers, the load mechanism is designed to be extensible from an architectural standpoint. Additional loaders can be supported by the introduction of pluggable modules. Each module is implemented in the Java programming language according to a LexBIG-provided interface, and registered to the loader runtime environment.
- Asserted Value Set Definition Loads – References a database load of an Asserted Value Set Source terminology to interpret and load value set definitions to the data model based LexGrid schema.

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