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Committee MemberPresentAbsent
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Elaine OstranderX
Deborah Knapp
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Jeff Trent
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Dawn DuvalX
Anju Angu Singh
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Amy LeblancX
Heather GardnerX
Cheryl LondonX
Christina MazckoX
Paula JacobsX
Renee ChambersX
Shaying ZhaoX
William Hendricks
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Outstanding Action Items

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ItemWhoNotes
Welcome & Roll CallGina Kuffel
New imputation paperElaine Ostrander
Alignment status of 1500 dog10KElaine Ostrander
  • Community using new German Shepherd reference from the Broad 
Timing of Variant ReleaseElaine Ostrander
Canine Reference Genome from the BroadElaine OstranderShaying Zhao
Pan Cancer StudyShaying Zhao
  • Breed prediction pipeline
  • The 15TB harmonized reads are generated from cases with matched tumor and normal samples both passing our comprehensive quality control measures, including breed validation and prediction using our software provided



Committee GoalsGinaCommittee GoalsToddBest Practices publication
  • Initial Outline on Box: https://nih.app.box.com/folder/137612017625
  • Elaine to potentially take the lead on this initiative
  • A milestone driven outline with dates and assigned tasks is needed
  • Set to begin work on this effort by mid August
  • Target date for submission is October 1, 2021
    • Variant filter file
      • Some of the filters are not well understood by the group
      • A discussion is needed to identify overlap and differences in variant calling filter files being using by various groups
      • Dependent on genome best practices for calling germ-line mutations

    Meeting Minutes (Not Verbatim)

    EO- Link to Michigan pipeline will be available soon. I can share with group when I have it.

    RC- About to do sequencing on a chunk of dogs, the imputation paper could be a great reference.

    EO- Helpful with low-pass sequencing.

    EO- There will be a release of all variants. Everything will be re-called since they aligned to the new GSD reference. 

    EO- We can have Reuben Buckley attend the meeting next time and give a Q & A. He is also in the alignment group.

    Previous Meeting Minutes (Not Verbatim)

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    DD- Reach out to Elaine through email and determine if she is willing to take the lead.

    Action items

    •  Elaine to send link to new GSD reference genome.