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Page History
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| Committee Member | Present | Absent |
|---|---|---|
| X | ||
| X | ||
| Warren Kibbe | X | |
| X | ||
| Gregory Tawa | X | |
| William Hendriks | X | |
| Matthew Breen | X | |
| Roel Verhaak | X |
Goals
- Review, discuss, and prioritize ICDC study submission proposals
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- Matthew & Warren to write an email request to Toby pertaining to formalization of a business plan for ICDC
- Musk, Philip (NIH/NCI) [C] to brush up on Nanostring documentation
- Greg to reach out to Christine Mazcko about potential biobanking resources for the organoids
- Kim, Erika (NIH/NCI) [E] will reach out to DCTD for patient derived repository to determine if canines are included: https://pdmr.cancer.gov/database/default.htm
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| Discussion Item | Who | Notes |
|---|---|---|
| Data submission request from Iowa State |
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| New data submission request from PRECINCT |
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| Data submission approved by Senior Advisory Committee |
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| PRECINCT Data Request Submission: Inhaled IL-15 Immunotherapy for Treatment of Lung Metastases | All |
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| Review of other Modiano publications: Other Modiano Publication Considerations.xlsx |
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| Study Updates |
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Minutes (Not Verbatim)
**Voting for Iowa State submission, only samples that have RNA-Seq data for Bladder Cancer and Healthy individuals**
In favor: Greg, Erika, Roel, Warren
**Questions answered from email sent to submitters on 10//22**
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- Will screening data be available in the future?
- Depends on the contract, model is being developed by our lab, the model is owned by the lab
- Are there publications?
- There is RNA-Seq data from a publication that is currently in review. This would be available nearly immediately.
- Will the organoids be made available to other researchers?
- CRO approach, open to collaboration in the future.
- As a researcher interested in testing a particular compound...
- There would be a MTA and we would test the compound using our organoids and share data back with the NIH.
- How do other labs reproduce research on the organoids?
- There is a paper coming out that gives exact specifications, collaborations are possible, but the organoids would stay at Iowa State. Open to colloabortions with industry and academia.
- Action items
Kuffel, Gina (NIH/NCI) [C] Seek votes from Will and Matthew through email.
