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Screening was carried out in a 384-well plate format at a single point concentration of 10 µg/mL with ≥2 replicates per well, and results of the HTS on 326,656 NPNPD fractions is available for download. Furthermore, confirmation of single-point hits was done in eight-point dose-response at a concentration of 0.08 to 10 µg/mL with the results also available for download. Summary of the screening methodology, analysis of the results of the HTS, as well as a small proof-of-concept study that demonstrates the identification of new natural products with selective anti-bacterial and anti-fungal activities can be found in Martinez-Fructuoso et al.¹ For further information, please contact the Natural Products Branch at NCINatProdRep@mail.nih.gov.

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