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The ISA-TAB file structure relies on three primary files - Investigation, Study, and Assay files. Data files specific to each assay can also be provided to capture assay specific measurements. nano-TAB leverages and extends ISA-TAB by introducing a Materials file for representing the structural composition of the nanomaterial. nano-TAB extends the ISA-TAB Study file which traditionally provides a mapping between studies and biological specimens, by referencing the Material file for mapping the study to nanomaterials or small molecules.
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