- Version Number and Release Date: 6.0, April 2014
- Primary audience: Investigators and Researchers
- Grid Enabled? Yes
- Compatibility Level: Not yet determined
- Installation Level: Intermediate - technical assistance may be required, download may require supporting infrastructure or software
- System Requirements: Provides web-based access to de-identified DICOM images, markups, and annotations using role based security. The NBIA download package is a ZIP package that includes the NBIA application, supporting libraries, RSNA Clinical Trial Processor (CTP) submission client/server (with NBIA modifications), and associated documentation.
Tool Overview
The National Biomedical Imaging Archive (NBIA) is a free and open source service and software application that enables users to securely store, search, and download diagnostic medical images, providing a searchable national repository integrating in vivo cancer images with clinical and genomic data. Using role-based security, NBIA provides web-based access to de-identified DICOM images, image markup, annotations, and rich metadata. The NBIA download package is a ZIP package that includes the NBIA application, supporting libraries, the RSNA MIRC application (with NBIA modifications), documentation, and a sample NBIA database. A web-based visualization and annotation tool, I-Response, is available to users of the NCI NBIA instance.I-Response provides immediate on-screen visualization of DICOM images integrated with NBIA query results and is to support persistence of annotations from client to NBIA archive.
Along with the Clinical Trial Processor software from the Radiological Society of North America, NBIA supports customized de-identification of images. NBIA is able to integrate with other imaging applications to cull various data types, such as image annotations, clinical data, genomic data, and other research files, such as RT objects. NBIA can also federate with other instances of NBIA to support the response of multiple NBIA servers to a single query.
NCI's hosted instance of NBIA is freely available and provides researchers and clinicians with a robust DICOM archive that can securely share and access images to enhance scientific research and support clinical decision making. Anyone can deploy a local node of NBIA and, using caGrid infrastructure, securely share data across the grid.
The ultimate goals of the project include:
- Creation of an imaging informatics infrastructure that provides cost-effective support for purpose-built and other databases as necessary, precluding the need to create separate infrastructure for each database.
- Development of searchable imaging reference libraries linked to clinical outcomes data to assist researchers and practitioners.
- Availability of the archive for mining and integration by the broader research and clinical community.
- Robust support for data-driven decision making in oncology and medical practice in general by clinicians throughout the world.
Installation and Downloads
NBIA Artifacts
NBIA provides a simplified approach to install on Linux and Windows platforms. Much of the installation process has been automated so that if you accept the default values, you can install NBIA by typing the single command ant. With the exception of the database, all supporting tools are automatically installed and configured as part of the installation. The installation package contains the binaries and scripts necessary to install the application, API, and grid service. Refer to the installation guide for details.
Documentation is available on the NBIA wiki.
Current Version
| NBIA 6.0 Artifacts | File | Size |
|---|---|---|
| NBIA Distribution Package | nbia_install_6.0.zip | 587 MB |
| NBIA grid client libraries (including caGrid libraries): | client-jars-full.zip | 14.3 MB |
| NBIA grid client libraries (nbia related jars only) | client-jars-nodeps.zip | 393 KB |
| CTP Client Package (including FileSender) | CTP_client.zip | 15.6 MB |
| NBIA Release Notes | release_notes.txt | 13 KB |
Previous Releases
| NBIA 5.2.1 Artifacts | File | Size |
|---|---|---|
| NBIA Distribution Package | nbia_install_5.2.1.zip | 499 MB |
| NBIA GUI Installer | nbia_gui_distribution_5.2.1.jar-201311261449.jar | 624 MB |
| NBIA grid client libraries (including caGrid libraries): | client-jars-full.zip | 14.3 MB |
| NBIA grid client libraries (nbia related jars only) | client-jars-nodeps.zip | 393 KB |
| CTP Client Package (including FileSender) | CTP_client.zip | 15.6 MB |
| NBIA Release Notes | release_notes.txt | 16 KB |
There is also an NBIA GitHub Respository 
Sign up for the NBIA User listserv to receive updates about this tool.
| NBIA 5.2 Artifacts | File | Size |
|---|---|---|
| NBIA Distribution Package | nbia_install_5.2.0.zip | 499 MB |
| NBIA GUI Installer | nbia_gui_distribution_5.2.0.jar-201309261655.jar | 624 MB |
| NBIA grid client libraries (including caGrid libraries): | client-jars-full.zip | 14.3 MB |
| NBIA grid client libraries (nbia related jars only) | client-jars-nodeps.zip | 393 KB |
| CTP Client Package (including FileSender) | CTP_client.zip | 15.6 MB |
| NBIA Release Notes | release_notes.txt | 16 KB |
| NBIA 5.1 Artifacts | Size |
|---|---|
| nbia_install_5.1.0.zip | 547 MB |
| nbia_gui_distribution_5.1.0.jar-201212201337.jar | 673 MB |
| client-jars-full.zip | 14.2 MB |
| client-jars-nodeps.zip | 388 KB |
| CTP_client.zip | 15.1 MB |
| release notes.txt | 4 KB |
| NBIA 5.0.2 Artifacts | Size |
|---|---|
| NBIA_5.0.2_installation_guide.pdf | 738 KB |
| nbia_5.0.2_release_notes.txt | 4 KB |
| NBIA_5.0_Users_Guide.pdf | 2.34 MB |
| nbia_CTP_Client_5.0.2.zip | 12.8 MB |
| nbia_grid_client-jars-full_5.0.2.zip | 13.03 MB |
| nbia_grid_client-jars-nodeps_5.0.2.zip | 371 KB |
| nbia_gui_distribution_5.0.2.jar | 513.27 MB |
| nbia_install_5.0.2.zip | 397.5 MB |
| NBIA 5.0.1 Artifacts | Size |
|---|---|
| NBIA_5.0_installation_guide.pdf | 703 KB |
| nbia_5.0.1_release_notes.txt | 4 KB |
| NBIA_5.0_Users_Guide.pdf | 2.34 MB |
| nbia_CTP_Client_5.0.1.zip | 12.8 MB |
| nbia_grid_client-jars-full_5.0.1.zip | 13.04 MB |
| nbia_grid_client-jars-nodeps_5.0.1.zip | 371 KB |
| nbia_gui_distribution_5.0.1.jar | 513.24 MB |
| nbia_install_5.0.1.zip | 397.48 MB |
| NBIA 5.0 Artifacts | |
|---|---|
| NBIA_5.0_installation_guide.pdf | 703 KB |
| nbia_5.0_release_notes.txt | 4 KB |
| NBIA_5.0_Users_Guide.pdf | 2.34 MB |
| nbia_CTP_Client_5.0.zip | 12.8 MB |
| nbia_grid_client-jars-full_5.0.zip | 13.04 MB |
| nbia_grid_client-jars-nodeps_5.0.zip | 371 KB |
| nbia_gui_distribution_5.0.0.jar | 513.24 MB |
| nbia_install_5.0.0.zip | 397.48 MB |
I-Response download
The Cedara I-Response software is needed to visualize image series selected in the NBIA search results page.
The Cedara I-Response software is available to all persons using the NBIA for research and clinical study who wish to access digital images stored on the NBIA. NCI/NBIA makes its best efforts to prevent and protect the Software from unauthorized disclosure or use. All rights, title, and interest in and to the I-Response software and any enhancements thereto and derivative works thereof, and all related documentation and materials, remain with the Cedara Software Corporation.
Cedara I-Response runs only on Windows® XP Professional and Microsoft® Windows® Vista operating systems with Service Pack 2.
I-Response Distribution Package - Cedara_I-Response_CS_2.zip is available for download.
After downloading Cedara I-Response, run Setup.exe to install.
Forum and Support
Support
Defects and Feature Requests
Open Source Development
Contact Application Support for information about open source development and NBIA.
Documentation and Training
Refer to NBIA Documentation.
Online help is available in the application.
No training materials are available. Refer to Presentations, Demos and Other Materials for an overview and demo.
Presentations, Demos and Other Materials
- NBIA Demonstration – 20-minute audio over slides and screencast (turn speakers on). If the slides appear to "freeze" during playback, press pause and then play to realign the playback stream.
- Download Demo Slides – download of the Power Point slides for this demonstration.
- Weekly Status Reports - Status reports of the operations and maintenance NBIA presented at our weekly meetings
- DICOM Image Viewers
- Getting started with CTP (Clinical Trials Processor)
- More information on Clinical Trial Processor (CTP)
- Web-based Tools For Imaging Research
- NBIA Mouse GBM
Integration with Other Tools
caIntegrator2 can query for imaging data in an instance of NBIA via a Java API. Once a group of patients is selected, you can access NBIA to review the patients images and associated metadata, and download the DICOM data as needed.
