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NCI Yeast Anticancer Drug Screen datasets - April 2002 release

  • Stage0
    • Data available for 87,264 compounds
      • 75,196 inactive (growth inhibition <70% in all strains)
      • 12,068 active (growth inhibition of at least 70% in at least 1 strain)
        • 5,777 active in all strains
    • Download Stage0 Dataset
      • Comma delimited file with NSC, DIFFINH (the difference between the duplicate growth inhibition measurements), AVEINH (the average of the duplicate growth inhibition measurements), STRAIN
      • File is 3.4 MB (zipped) and unzips to 14.6 MB
  • Stage1
    • Data available for 14,837 compounds
      • At the high dose (50 microM)
        • 5,491 inactive (growth inhibition <70% in all strains)
        • 9,346 active (growth inhibition of at least 70% in at least 1 strain)
          • 5,433 active in all strains
      • At the low dose (5 microM)
        • 12,244 inactive (growth inhibition <70% in all strains)
        • 2,593 active (growth inhibition of at least 70% in at least 1 strain)
          • 1,007 active in all strains
    • Download Stage1 dataset
      • Comma delimited file with NSC, DIFFINH (the difference between the duplicate growth inhibition measurements), AVEINH (the average of the duplicate growth inhibition measurements), STRAIN, microM
      • File is 915KB (zipped) and unzips to 5.0 MB
  • Stage2
    • Data available for 2,189 compounds
      • 475 inactive
      • 1,714 active
        • 692 have similar activity in all strains
    • Download Stage2 dataset
      • Comma delimited file with NSC, STRAIN, DIFFINH (the difference between the duplicate growth inhibition measurements), AVEINH (the average of the duplicate growth inhibition measurements), microM
      • File is 691KB (zipped) and unzips to 3.8 MB

Email questions to: Susan Holbeck [holbecks@mail.nih.gov]

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