Date
Attendees
Committee Member | Present | Absent |
---|---|---|
X | ||
X | ||
Warren Kibbe | X | |
X | ||
Gregory Tawa | X | |
William Hendriks | X | |
Matthew Breen | X | |
Roel Verhaak | X |
Goals
- Review, discuss, and prioritize ICDC study submission proposals
Outstanding Action items
- Matthew & Warren to write an email request to Toby pertaining to formalization of a business plan for ICDC.
- Musk, Philip (NIH/NCI) [C] to brush up on Nanostring documentation.
Agenda
Discussion Item | Who | Notes |
---|---|---|
New data submission request |
| |
Data submission approved by Senior Advisory Committee |
| |
PRECINCT Data Request Submission: Inhaled IL-15 Immunotherapy for Treatment of Lung Metastases | All |
|
Review of other Modiano publications: Other Modiano Publication Considerations.xlsx |
| |
Study Updates |
|
Minutes (Not Verbatim)
**Discussion of Q&A email thread with data submitters of Tissue & Organoid study**
GT- Some science associated with cancer and IBD, evident link but not an expert in this area.
PM - The submission seems to be more about IBD than it is about cancer based on our discussion
RV - Is this a good fit for our data repo? Would sending it away prevent this data from ever being made accessible to the public?
RV - How many of the patient samples will ultimately have omics data associated with them?
WK - Struggling with the strong rationale to import this data.
EK - Need metadata for the cancer related samples.
WK - Is there a place where these organoids can be validated and made available for other researchers?
GT - There are members of the SC that can help with depositing samples to and getting samples from, Christine Mazcko is our contact.
RV - The submission is beyond the scope of our resource, however we should help to make this data available.
GT - What is their plan is to have genomic coverage for all individuals?
WK - In favor of finding a way to accept.
EK - Potentially leverage resources from DCTD, looks like their grant involves drug development for bladder cancer.
WK - Moving into the drug screening space would be valuable.
Action items
- Greg to reach out to Christine Mazcko about potential biobanking resources for the organoids
- Kim, Erika (NIH/NCI) [E] will reach out to DCTD for patient derived repository to determine if canines are included: https://pdmr.cancer.gov/database/default.htm
- Kuffel, Gina (NIH/NCI) [C] to send email summarizing plan to data submitter