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Since 1997, EVS has worked with many partners to build shared content and services, so that information can be effectively exchanged, interpreted and analyzed while minimizing overall effort and cost.  Much of this content has been created and published using NCI Thesaurus and NCI Metathesaurus, as outlined below and described in more detail in the individual user profiles later, where other shared development efforts are also described.

NCI Thesaurus (NCIt)

NCI Thesaurus (NCIt) is NCI's core reference terminology. Over the last 10 years, it has also been adopted by FDA, CDISC, NCPDP and other partners as a shared standards development and coding environment, allowing participants to compare and harmonize with each other's content while taking advantage of full-text definitions, codes, and other features.

About 40,000 out of the nearly 100,000 current NCIt concepts have terms from both EVS and from one or more of these other sources. The chart below gives the last available detailed breakdown, for June 2010. Note that some partners have used NCI terms rather than tagging their own, so these figures understate the true extent of cross-source sharing.

NCIt concepts with terms from tagged outside sources (11.09d: September 2011)

NCIt concepts with tagged synonyms from each outside source (11.09d: September 2011)

Source

NCIt Concepts

BIOCARTA

335

BIOCARTA

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335

BRIDG

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1,139

CADSR

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27

CDC

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919

CDISC

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5,633

CRCH

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424

CTCAE

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6,368

CTRM

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4,421

DCP

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902

DICOM

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114

DTP

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697

FDA

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15,772

HL7

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125

ICH

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215

JAX

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156

KEGG

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255

NCICB

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4

NCI-GLOSS

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5,157

NCPDP

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515

NICHD

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886

PID

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169

RENI

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311

SEER

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62

UCUM

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287

ZFin

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25

NCI Metathesaurus (NCIm)

NCI Metathesaurus (NCIm) was started in the late 1990s to gather up, translate between, and publish the many terminologies used by NCI, including some created in part or whole within NCI. Development of NCI Thesaurus started within NCIm as NewPDQ, an effort to extend and restructure the PDQ Terminology long used to code cancer clinical trial, research and public information resources. NCIm continues to provide a vital environment for EVS collaboration with NCI and other partners to develop, map and publish terminologies of shared interest, and responds to the requirements of a broad range of stakeholders within the cancer research and biomedical community.

NCIm terminologies (201105: May 2011)

Source Label

Source Name

AOD

Alcohol and Other Drug Thesaurus, 2000

AOT

Authorized Osteopathic Thesaurus, 2003

BioC

BioCarta online maps of molecular pathways, adapted for NCI use, 1105E

BRIDG

Biomedical Research Integrated Domain Group Model, 1105E

CBO

Clinical Bioinformatics Ontology, 2011_02

CCS

Clinical Classifications Software, 2005

CDC

U.S. Centers for Disease Control and Prevention, 1105E

CDISC

Clinical Data Interchange Standards Consortium, 1105E

COH

City of Hope, 1105E

COSTAR

COSTAR, 1989-1995

CRCH

Cancer Research Center of Hawaii Nutrition Terminology, 1105E

CSP

CRISP Thesaurus, 2006

CST

COSTART, 1995

CTCAE

Common Terminology Criteria for Adverse Events, 1105E

CTEP

Cancer Therapy Evaluation Program, 2004

DCP

NCI Division of Cancer Prevention Program, 1105E

DICOM

Digital Imaging Communications in Medicine, 1105E

DTP

NCI Developmental Therapeutics Program, 1105E

DXP

DXplain, 1994

FDA

U.S. Food and Drug Administration, 1105E

FMA

Foundational Model of Anatomy Ontology, 2_0

GO

Gene Ontology, 2010_04_01

HCPCS

Healthcare Common Procedure Coding System, 2010

HL7V3.0

HL7 Vocabulary Version 3.0, 2006_05

HUGO

HUGO Gene Nomenclature, 2010_05

ICD10

ICD10, 1998

ICD10AE

ICD10, American English Equivalents, 1998

ICD10CM

International Classification of Diseases, 10th Edition, Clinical Modification, 2010_03

ICD10PCS

ICD-10-PCS, 2009

ICD9CM

International Classification of Diseases, Ninth Revision, Clinical Modification, 2011

ICDO

International Classification of Diseases for Oncology, 3rd Edition, 2000

ICH

International Conference on Harmonization, 1105E

ICPC

International Classification of Primary Care, 1993

ICPC2ICD10ENG

ICPC2 - ICD10 Thesaurus, 200412

JAX

Jackson Laboratories Mouse Terminology, adapted for NCI use, 1105E

KEGG

KEGG Pathway Database, 1105E

LNC

Logical Observation Identifier Names and Codes, 232

MCM

McMaster University Epidemiology Terms, 1992

MDBCAC

Mitelman Database of Chromosome Aberrations in Cancer, 2005_12

MDR

Medical Dictionary for Regulatory Activities Terminology, 14.0

MEDLINEPLUS

MedlinePlus Health Topics, 20080614

MGED

MGED Ontology, 131

MSH

Medical Subject Headings, 2011_2010_08_30

MTH

UMLS Metathesaurus, 2010AB

MTHFDA

Metathesaurus FDA National Drug Code Directory, 2010_08_02

MTHHH

Metathesaurus HCPCS Hierarchical Terms, 2010

MTHICD9

International Classification of Diseases, Ninth Revision, Clinical Modification, Metathesaurus additional entry terms, 2011

MTHICPC2ICD107B

ICPC2 - ICD10 Thesaurus, 7-bit Equivalents, 0412

MTHICPC2ICD10AE

ICPC2 - ICD10 Thesaurus, American English Equivalents, 0412

MTHMST

Metathesaurus Version of Minimal Standard Terminology Digestive Endoscopy, 2001

MTHSPL

Metathesaurus FDA Structured Product Labels, 2010_08_27

NCBI

NCBI Taxonomy, 2010_04_29

NCI

National Cancer Institute Thesaurus, 2011_05E

NCI-GLOSS

NCI Dictionary of Cancer Terms, 1105E

NCI-HL7

NCI Health Level 7, 1105E

NCIMTH

NCI Metathesaurus

NCISEER

NCI SEER ICD Neoplasm Code Mappings, 1999

NCPDP

National Council for Prescription Drug Programs, 1105E

NDFRT

National Drug File, 2010_09_07

NICHD

National Institute of Child Health and Human Development, 1105E

NPO

NPO: NanoParticle Ontology for Cancer Nanotechnology Research, 2010_10_31

OMIM

Online Mendelian Inheritance in Man, 2010_04_08

PDQ

Physician Data Query, 2010_08_06

PID

National Cancer Institute Nature Pathway Interaction Database, 1105E

PMA

Portfolio Management Application, 2010

PNDS

Perioperative Nursing Data Set, 2nd edition, 2002

QMR

Quick Medical Reference (QMR), 1996

RADLEX

RadLex, 3_33

RENI

Registry Nomenclature Information System, 1105E

RXNORM

RxNorm Vocabulary, 10AA_100907F

SNOMEDCT

SNOMED Clinical Terms

SPN

Standard Product Nomenclature, 2003

SRC

Metathesaurus Source Terminology Names

UCUM

Unified Code for Units of Measure, 1105E

UMD

UMDNS: product category thesaurus, 2010

USPMG

USP Model Guidelines, 2004

UWDA

University of Washington Digital Anatomist, 1.7.3

VANDF

Veterans Health Administration National Drug File, 2010_07_26

ZFIN

Zebrafish Model Organism Database, 1105E

[details on NCIm collaborations and concept/term statistics pending]

| BIOCARTA | 335 |

BRIDG

1139

CADSR

27

CDC

919

CDISC

5633

CRCH

424

CTCAE

6368

CTRM

4421

DCP

902

DICOM

114

DTP

697

FDA

15772

HL7

125

ICH

215

JAX

156

KEGG

255

NCICB

4

NCI-GLOSS

5157

NCPDP

515

NICHD

886

PID

169

RENI

311

SEER

62

UCUM

287

ZFin

25

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