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Long NameDiagnosis Metastasis NCI Standard Template
DefinitionThe collection of CDEs used in the metastasis module.
ContextcaBIG
Protocol Long NameNCI Standard Template Forms
WorkflowDRAFT NEW
TypeCRF
Public ID3918521
Version1.0
Module Long NameModule InstructionsQuestionCDECDE Public IDCDE VersionValue Domain Data TypeValue Domain Unit of MeasureDisplay FormatValid ValueForm Value Meaning TextForm Value Meaning Desc.
Mandatory Diagnosis Metastasis QuestionsThese items must be included when this data is collected for reporting.
Metastatic Sites of InvolvementMetastatic Disease Anatomic Site Name30298151.0CHARACTER
AbdomenAbdominal CavityThe portion of the body that lies between the thorax and the pelvis.
Abdomen/PelvisAbdomen and PelvisThe portion of the body that lies between the thorax and the pelvis.: An article which expresses the relation of connection or addition. It is used to conjoin a word with a word, a clause with a clause, or a sentence with a sentence.: The structure of the vertebrate skeleton supporting the lower limbs in humans and the hind limbs or corresponding parts in other vertebrates.: Named locations of, or within, the body.
Abdominal wallAbdominal wallThe tissues that surround the organs that are present within the abdominal cavity. The abdominal wall tissue is composed of layers of fat, parietal peritoneum, fascia, and muscles.
AcetabulumAcetabulumTwo cup shaped areas, one each on the lateral side of the lower pelvis that house the head of the femur to form the ball and socket joint of the hip.
AdenoidTonsillar TissueA fold of lymphatic tissue covered by ciliated epithelium at the very back of the nose, in the roof of the nasopharynx.
AdiposeAdipose TissueConnective tissue composed of fat cells lodged in the meshes of areolar tissue.
Adrenal glandAdrenal GlandPaired glands situated in the retroperitoneal tissues at the superior pole of each kidney.
Alveolar RidgeAlveolar RidgeOf or relating to the alveoli.: Any long raised border or margin of a bone or tooth or membrane.
Amniotic FluidAmniotic FluidThe fluid within the amniotic cavity which surrounds and protects the developing embryo. It is initially produced by the amnion and then later by the lungs and kidneys. The amount at term normally varies from 500 to 2000 ml.
Ampulla of VaterAmpulla of VaterA dilation of the duodenal papilla that is the opening of the juncture of the common bile duct and the main pancreatic duct. (MeSH)
Anal canalAnal CanalThe lower opening of the digestive tract, lying in the cleft between the buttocks, through which fecal matter is extruded.
Anal sphincterAnal SphincterThe area that includes the anus and the perianal skin.: A ring-shaped muscle that relaxes or tightens to open or close a passage or opening in the body. Examples are the anal sphincter (around the opening of the anus) and the pyloric sphincter (at the lower opening of the stomach).
AnkleAnkleA gliding joint between the distal ends of the tibia and fibula and the proximal end of the talus.
AnorectumAnorectum(AY-nus) The opening of the rectum to the outside of the body.: An article which expresses the relation of connection or addition. It is used to conjoin a word with a word, a clause with a clause, or a sentence with a sentence.: The terminal portion of the gastrointestinal tract, extending from the rectosigmoid junction to the anal canal.: Named locations of, or within, the body.
Antecubital fossaAntecubital FossaThe hinge joint between the forearm and upper arm or the corresponding joint in the forelimb of a quadruped.: A concavity in a surface, especially an anatomical depression.
AntrumAntrum PyloriThe initial part of the pyloric canal of the stomach. This site contains endocrine cells that produce gastrin and somatostatin.
AnusAnus(AY-nus) The opening of the rectum to the outside of the body.
AortaAortaThe major arterial trunk that carries oxygenated blood from the left ventricle into the ascending aorta behind the heart, the aortic arch, through the thorax as the descending aorta and through the abdomen as the abdominal aorta; it bifurcates into the left and right common iliac arteries.
Aortic BodyAortic BodyA small mass that is located in the inferior surface of the aortic arch. It functions as a peripheral chemoreceptor and is composed of glomus cells.
AppendixAppendixSmall tissue projection existing as a cecal diverticulum with a questionable history of vestigial versus specialized organ.
Aqueous FluidAqueous FluidThe clear, watery fluid which fills the anterior and posterior chambers of the eye. It has a refractive index lower than the crystalline lens, which it surrounds, and is involved in the metabolism of the cornea and the crystalline lens. (Cline et al., Dictionary of Visual Science, 4th ed, p319)
ArmArmTechnically the part of the superior limb between the shoulder and the elbow but commonly used to refer to the whole superior limb.
ArteryArteryThe vessels carrying blood away from the heart.
Ascending colonAscending ColonThe first part of the colon (large intestine) that starts in the right lower quadrant of the abdomen and ends at the transverse colon in the right upper quadrant of the abdomen.
Ascending Colon Hepatic FlexureAscending Colon Hepatic FlexureThe first part of the colon (large intestine) that starts in the right lower quadrant of the abdomen and ends at the transverse colon in the right upper quadrant of the abdomen.: The bend of the colon at the juncture of its ascending and transverse portions.
AscitesAscitesAccumulation of fluid in the peritoneal cavity. The fluid may be serous, hemorrhagic, or the result of tumor metastasis to the peritoneum. -- 2004
Auditory canalAuditory CanalOf or relating to the process of hearing.: A bodily passage or tube lined with epithelial cells and conveying a secretion or other substance.
Autonomic nervous systemAutonomic Nervous SystemThe part of the nervous system of vertebrates that controls involuntary actions of the smooth muscles and heart and glands.
AxillaAxillaAxilla; the hollow under the arm where it is joined to the shoulder.
BackBackThe dorsal area between the base of the neck and the sacrum.
Bile ductBile DuctA tube through which bile passes in and out of the liver.
BladderBladderThe distensible sac-like organ that functions as a reservoir of urine, collecting from the kidneys and eliminating via the urethra.
BloodBloodA liquid tissue; its major function is to transport oxygen throughout the body. It also supplies the tissues with nutrients, removes waste products, and contains various components of the immune system defending the body against infection. Several hormones also travel in the blood.
Blood vesselBlood VesselA tube through which the blood circulates in the body. Blood vessels include a network of arteries, arterioles, capillaries, venules, and veins.
BoneBoneConnective tissue that forms the skeletal components of the body.
Bone marrowBone MarrowThe tissue occupying the spaces of bone. It consists of blood vessel sinuses and a network of hematopoietic cells which give rise to the red cells, white cells, and megakaryocytes.
BowelBowel(in-TES-tin) The long, tube-shaped organ in the abdomen that completes the process of digestion. There is both a large intestine and a small intestine. Also called the bowel.
BrainBrainAn organ composed of grey and white matter containing billions of neurons that is the center for intelligence and reasoning. It is protected by the bony cranium.
Brain stemBrain StemThe part of the brain that is connected to the spinal cord.
BreastBreastOne of two hemispheric projections of variable size situated in the subcutaneous layer over the pectoralis major muscle on either side of the chest.
Broad ligamentBroad LigamentA broad fold of peritoneum that extends from the side of the uterus to the wall of the pelvis. (MeSH)
BronchioleBronchiole(BRON-kee-olz) The tiny branches of air tubes in the lungs.
BronchusBronchusTubular structure in continuation with the trachea, serving as air passage. It terminates in the lung (terminal bronchiole).
Bronchus and LungBronchus And LungTubular structure in continuation with the trachea, serving as air passage. It terminates in the lung (terminal bronchiole).: An article which expresses the relation of connection or addition. It is used to conjoin a word with a word, a clause with a clause, or a sentence with a sentence.: One of a pair of viscera occupying the pulmonary cavities of the thorax, the organs of respiration in which aeration of the blood takes place. As a rule, the right lung is slightly larger than the left and is divided into three lobes (an upper, a middle, and a lower or basal), while the left has but two lobes (an upper and a lower or basal). Each lung is irregularly conical in shape, presenting a blunt upper extremity (the apex), a concave base following the curve of the diaphragm, an outer convex surface (costal surface), an inner or mediastinal surface (mediastinal surface), a thin and sharp anterior border, and a thick and rounded posterior border.: Named locations of, or within, the body.
BrowEyebrowNo Value Exists
Buccal cavityBuccal CavityThe region consisting of the vestibulum oris, the narrow cleft between the lips and cheeks, and the teeth and gums, and the cavitas oris propria.
Buccal mucosaBuccal MucosaThe mucosal membranes located on the inside of the cheek, in the buccal cavity.
ButtockButtockEither of the fleshy mounds in the rear pelvic area of the human body formed by the gluteal muscles.
CalfCalfThe posterior aspect of the lower extremity that extends from the knee to the foot.
CapillaryCapillaryTiny blood vessels that connect the arterioles with the venules.
CardiaGastric CardiaThe area around the esophagogastric mucosal junction where the esophageal mucosa transitions into the gastric mucosa.
CarinaCarinaA ridge or ridge-like structure. In humans it usually refers to the trachea. The carina of trachea is part of the lowest tracheal cartilage which is placed between the orifices of the two bronchi.
Carotid arteryCarotid ArteryEither of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.
Carotid bodyCarotid BodyA cluster of cells that function as chemo-receptors, located at the bifurcation of the carotid artery. Its main purpose is to detect changes in the composition of arterial blood.
CartilageCartilageA type of connective tissue composed of chondrocytes and an extracellular matrix, composed of collagen, elastin, and ground substance. There are three types of cartilage; namely elastic, hyaline, and fibrocartilage.
CecumCecumA blind pouch-like commencement of the colon in the right lower quadrant of the abdomen at the end of the small intestine and the start of the large intestine.
Central Line CatheterCentral Venous Access CatheterA tube surgically placed into a blood vessel for the purpose of giving intravenous fluid and drugs. It also can be used to obtain blood samples. This device avoids the need for separate needle insertions for each infusion or blood test. Examples of these devices include Hickman catheters, which require clamps to make sure the valve is closed, and Groshong catheters, which have a valve that opens as fluid is withdrawn or infused and remains closed when not in use.
Central nervous systemCentral Nervous SystemThe main information-processing organs of the nervous system, consisting of the brain, spinal cord, and meninges.
CerebellumCerebellumThe portion of the brain located at the base of the skull that is responsible for balance, equilibrium and movement.
Cerebral cortexCerebral CortexThe outer layer of the cerebrum composed of neurons and unmyelinated nerve fibers. It is responsible for memory, attention, consciousness and other high mental functions.
Cerebrospinal fluidCerebrospinal fluidThe fluid that is contained within the brain ventricles, the subarachnoid space and the central canal of the spinal cord.
CerebrumCerebral Hemisphere(seh-REE-bral HEM-iss-feer) One half of the cerebrum, the part of the brain that controls muscle functions and also controls speech, thought, emotions, reading, writing, and learning. The right hemisphere controls the muscles on the left side of the body,
Cervical spineCervical spineThose vertebrae immediately behind (caudal to) the skull, C1-C7 in man.
Cervical/Thoracic/Lumbar spineCervical and Thoracic and Lumbar Spine Relating to a neck, or cervix, in any sense.: (thor-ASS-ik) Having to do with the chest.: Those vertebrae between the ribs and the pelvis, L1-L5 in man.: The spinal or vertebral column.
CervixCervix(SER-viks) The lower, narrow end of the uterus that forms a canal between the uterus and vagina.
ChestChestThe anterior side of the thorax from the neck to the abdomen. The shape of the chest is often regarded as potential insight into a disease process, as in the case of barrel chest and respiratory dysfunction.
Chest wallChest WallThe total system of structures outside the lungs that move as a part of breathing; it includes all structures from the skin to the parietal pleura.
Chest/Abdomen/PelvisChest and Abdomen and PelvisThe part of the human body between the neck and the diaphragm or the corresponding part in other vertebrates.: The portion of the body that lies between the thorax and the pelvis.: The structure of the vertebrate skeleton supporting the lower limbs in humans and the hind limbs or corresponding parts in other vertebrates.: Named locations of, or within, the body.
Chest/PelvisChest and PelvisThe part of the human body between the neck and the diaphragm or the corresponding part in other vertebrates.: An article which expresses the relation of connection or addition. It is used to conjoin a word with a word, a clause with a clause, or a sentence with a sentence.: The structure of the vertebrate skeleton supporting the lower limbs in humans and the hind limbs or corresponding parts in other vertebrates.: Named locations of, or within, the body.
ChinMentumThe part of the face below the lower lip and including the protruding part of the lower jaw.
ClavicleClavicleA bone of the upper extremity that articulates with the acromion process of the scapula on one end and the sternum on the other.
ClitorisClitorisThe erectile tissue in the vulva. It is composed of the corpora cavernosa and the glans clitoris.
CNS + SystemicCentral Nervous System And Systemic Anatomic SiteThe part of the nervous system that consists of the brain, spinal cord, and meninges. : An article which expresses the relation of connection or addition. It is used to conjoin a word with a word, a clause with a clause, or a sentence with a sentence.: (sis-TEM-ik) Affecting the entire body.: Named locations of, or within, the body.
ColonColonThe part of the large intestine measured from the cecum to the rectum consisting of ascending, transverse, descending and sigmoid portions. The purpose of the colon is to remove water from digested food prior to excretion.
Colon and rectumColon and RectumThe part of the large intestine measured from the cecum to the rectum consisting of ascending, transverse, descending and sigmoid portions. The purpose of the colon is to remove water from digested food prior to excretion.: An article which expresses the relation of connection or addition. It is used to conjoin a word with a word, a clause with a clause, or a sentence with a sentence.: The terminal portion of the gastrointestinal tract, extending from the rectosigmoid junction to the anal canal.: Named locations of, or within, the body.
Colon, mucosa onlyColon MucosaThe part of the large intestine measured from the cecum to the rectum consisting of ascending, transverse, descending and sigmoid portions. The purpose of the colon is to remove water from digested food prior to excretion.: The moist tissue that lines some organs and body cavities (such as the nose, mouth, lungs) and makes mucus (a thick, slippery fluid).
Common ductCommon Bile DuctBile ducts are passageways that carry bile. Two major bile ducts come together into a "trunk"-the common bile duct which empties into the upper part of the small intestine (the part next to the stomach).
ConjunctivaConjunctivaA thin, transparent mucous membrane that covers the posterior surface of lids (palpebral conjunctiva) and the outer surface of the sclera (bulbar conjunctiva).
Connective tissueConnective TissueSupporting tissue that surrounds other tissues and organs. Specialized connective tissue includes bone, cartilage, blood, and fat.
Cranial NerveCranial NerveAny of the 12 paired nerves that originate in the brain stem.
Descending colonDescending ColonThe fourth portion of the large intestine (colon) that communicates with the transverse colon in the left-upper quadrant of the abdomen and the rectum below.
DiaphragmDiaphragmFibromuscular tissue that separates the thoracic from the abdominal cavity. It increases the volume of the thoracic cavity through contractions, thus facilitating respiration.
DuodenumDuodenum(doo-ah-DEE-num) The first part of the small intestine.
EarEarThe organ of hearing: composed of the external ear, which includes the auricle and the external acoustic, or auditory, meatus; the middle ear, or the tympanic cavity with its ossicles; and the internal ear or inner ear, or labyrinth, which includes the semicircular canals, vestibule, and cochlea. SEE ALSO auricle. SYN auris.
Ear canalEar CanalThe organ of hearing: composed of the external ear, which includes the auricle and the external acoustic, or auditory, meatus; the middle ear, or the tympanic cavity with its ossicles; and the internal ear or inner ear, or labyrinth, which includes the semicircular canals, vestibule, and cochlea. SEE ALSO auricle. SYN auris.: A bodily passage or tube lined with epithelial cells and conveying a secretion or other substance.
Ear, Pinna (External)External EarThe external part of the ear.
EffusionEffusionA collection of fluid in a body cavity. It may be the result of a non-neoplastic disorder (e.g. heart failure) or a tumor (e.g. carcinoma of the lung). -- 2003
ElbowElbow JointThe hinge joint between the forearm and upper arm or the corresponding joint in the forelimb of a quadruped.
Endocrine glandEndocrine GlandDuctless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions.
EpididymisEpididymisA crescent-like structure located in the upper and posterior surfaces of the testis. It consists of the efferent ductules and the duct of the epididymis. It facilitates the maturation of sperm that is produced in the testis.
Epidural spaceEpidural Spinal Canal SpaceSpace between the dura mater and the walls of the vertebral canal.
Esophagogastric junctionGastroesophageal JunctionThe anatomical location where the esophagus joins to the stomach.
EsophagusEsophagusThe portion of the digestive canal between the pharynx and stomach. It is about 25 cm long and consists of three parts: the cervical part, from the cricoid cartilage to the thoracic inlet; thoracic part, from thoracic inlet to the diaphragm; and abdominal part, below the diaphragm to the cardiac opening of the stomach.
Esophagus, Mucosa onlyEsophageal MucosaOf or relating to the esophagus.: The moist tissue that lines some organs and body cavities (such as the nose, mouth, lungs) and makes mucus (a thick, slippery fluid).
Extra-adrenalExtra-adrenalExtra-adrenal
ExtremitiesExtremitiesBody limbs, consisting of right upper and lower (arm and leg) and left upper and lower (arm and leg).
EyeEyeThe organ of sight or vision. (On-line Medical Dictionary)
Fallopian tubeFallopian tubeOne of a pair of tubes that extend from the uterus to each of the ovaries. Following ovulation the egg travels down the fallopian tube to the uterus where fertilization may or may not occur.
FemurFemurThe longest and largest bone of the skeleton, it is situated between the hip and the knee.
FibulaFibulaThe bone of the lower leg lateral to and smaller than the tibia. In proportion to its length, it is the most slender of the long bones.
FingerFingerAny of the digits of the hand.
Floor of MouthFloor of MouthThe area of the mouth under the ventral surface of the tongue.
FluidBody Fluid or SubstanceLiquid and semi liquid substances produced by living organisms to fulfill specific functions or excreted as waste; does not include hormones or enzymes.
FootFootThe terminal part of the lower extremity, especially the part below the ankle.
ForearmForearmThe structure on the upper limb, between the elbow and the wrist.
ForeheadForeheadThe part of the face between the eyebrows and the normal hairline.
ForeskinMale PrepuceA fold of skin covering the tip of the penis.
Frontal lobeFrontal LobeThe anterior part of the cerebral hemisphere.
Fundus of stomachFundusThe larger part of a hollow organ that is farthest away from the organ's opening. The bladder, gallbladder, stomach, uterus, eye, and cavity of the middle ear all have a fundus.
GallbladderGallbladderA pear-shaped organ just below the liver that stores the bile secreted by the liver, delivering the bile through the bile ducts into the intestines to help with digestion.
GangliaGanglionA cluster of nervous tissue principally composed of neuronal cell bodies external to the central nervous system (CNS).
Gastroesophageal JunctionGastroesophageal JunctionThe anatomical location where the esophagus joins to the stomach.
Gastrointestinal tractGastrointestinal TractThe upper gastrointestinal (GI) tract is comprised of mouth, pharynx, esophagus and stomach while the lower GI tract consists of intestines and anus. The primary function of the GI tract is to ingest, digest, absorb and ultimately excrete food stuff.
GenitourinaryGenitourinaryOf or related to the genital and urinary organs or their functions.
GroinInguinal RegionThe lower region of the anterior abdominal wall located laterally to the pubic region.
GumGingivaThe mucous membrane-covered tissue of the jaws that surrounds the bases of the teeth.
HandHandThe distal portion of the upper extremity. It consists of the carpus, metacarpus, and digits.
Hard palateHard PalateThe bony anterior part of the roof of the mouth separating the nose from the mouth.
Head - face or neck, NOSHead (Face Or Neck , Not otherwise specified)The anterior or superior part of an animal, containing the brain, or chief ganglia of the nervous system, the mouth, and in the higher animals, the chief sensory organs. (On-line Medical Dictionary): The anterior portion of the head extending from the forehead to the chin and ear to ear. The facial structures contain the eyes, nose and mouth, cheeks and jaws.: An article used to connect words, phrases, or clauses representing alternatives; used to connect alternative terms for the same thing; used in correlation; used to correct or rephrase what was previously said; otherwise.: The region that connects the head to the rest of the body.: Not characterized in any other way.: Named locations of, or within, the body.
Head/NeckHead and NeckThe anterior or superior part of an animal, containing the brain, or chief ganglia of the nervous system, the mouth, and in the higher animals, the chief sensory organs. (On-line Medical Dictionary): An article which expresses the relation of connection or addition. It is used to conjoin a word with a word, a clause with a clause, or a sentence with a sentence.: The region that connects the head to the rest of the body.: Named locations of, or within, the body.
Head/Neck/Chest/Abd/PelvisHead and Neck and Chest and Abdomen and PelvisThe anterior or superior part of an animal, containing the brain, or chief ganglia of the nervous system, the mouth, and in the higher animals, the chief sensory organs. (On-line Medical Dictionary): The region that connects the head to the rest of the body.: The part of the human body between the neck and the diaphragm or the corresponding part in other vertebrates.: The portion of the body that lies between the thorax and the pelvis.: The structure of the vertebrate skeleton supporting the lower limbs in humans and the hind limbs or corresponding parts in other vertebrates.: Named locations of, or within, the body.
HeartHeartA hollow muscular organ which receives the blood from the veins and propels it into the arteries. It is divided by a musculomembranous septum into two halves -- right or venous and left or arterial -- each of which consists of a receiving chamber (atrium) and an ejecting chamber (ventricle). SYN cor, coeur.
Hepatic ductHepatic DuctAny of the three ducts associated with the liver including the right hepatic duct, left hepatic duct and common hepatic duct.
HilumHilumA depression or fissure where vessels or nerves or ducts enter a bodily organ.
HipHipThe lateral prominence of the pelvis from the waist to the thigh.
HumerusHumerusThe upper arm bone between the shoulder and elbow.
HypopharynxHypopharynx (Laryngopharynx)The portion of the pharynx between the inferior portion of the oropharynx and the larynx.
IleumIleumThe final section of the small intestine.
IliumIliumThe broad, dorsal, upper, and widest of the three principal bones composing either half of the pelvis.
IntestineIntestine(in-TES-tin) The long, tube-shaped organ in the abdomen that completes the process of digestion. There is both a large intestine and a small intestine. Also called the bowel.
IschiumIschiumThe most posterior and ventral bone making up the pelvis.
JawJawThe bones of the skull that frame the mouth and serve to open it; the bones that hold the teeth.
JejunumJejunumThe portion of the small intestine that extends from the duodenum to the ileum.
JointsJointThe connection point between two bones or skeletal elements. The joint may be fixed or movable.
KidneyKidneyOne of the two organs that excrete the urine. The kidneys are bean-shaped organs (about 11 cm long, 5 cm wide, and 3 cm thick) lying on either side of the vertebral column, posterior to the peritoneum, about opposite the twelfth thoracic and first three lumbar vertebrae. SYN ren, nephros.
KneeKnee JointA hinge joint in the human leg connecting the tibia and fibula with the femur and protected in front by the patella.
Lacrimal GlandLacrimal GlandPaired, almond-shaped exocrine glands situated superior and posterior to each orbit of the eye that produce and secrete the watery serous component of tears.
Large bowelLarge IntestineA muscular tube that extends from the end of the small intestine to the anus. (NCI)
LaryngopharynxHypopharynx (Laryngopharynx)The portion of the pharynx between the inferior portion of the oropharynx and the larynx.
LarynxLarynxThe organ of voice production; the part of the respiratory tract between the pharynx and the trachea; it consists of a framework of cartilages and elastic membranes housing the vocal folds and the muscles which control the position and tension of these elements.
LegLegCommonly used to refer to the whole lower limb but technically only the part between the knee and ankle.
LeptomeningesLeptomeningesThe two innermost layers of tissue that cover the brain and spinal cord, the arachnoid mater and the pia mater.
LigamentLigamentBand of fibrous tissue connecting bone to bone or cartilage to bone thereby supporting or strengthening a joint.
LipLipEither of the two fleshy, full-blooded margins of the mouth. (MeSH)
LiverLiverA large organ located in the upper abdomen. The liver cleanses the blood and aids in digestion by secreting bile.
Liver and intrahepatic ductLiver and Intrahepatic DuctA triangular-shaped organ located under the diaphragm in the right hypochondrium. It is the largest internal organ of the body, weighting up to 2 kg. Metabolism and bile secretion are its main functions. It is composed of cells which have the ability to regenerate.: Refers to the liver.: A tube that carries various secretions from one part of the body to another.: Named locations of, or within, the body.
Liver/SpleenLiver and SpleenA triangular-shaped organ located under the diaphragm in the right hypochondrium. It is the largest internal organ of the body, weighting up to 2 kg. Metabolism and bile secretion are its main functions. It is composed of cells which have the ability to regenerate.: An article which expresses the relation of connection or addition. It is used to conjoin a word with a word, a clause with a clause, or a sentence with a sentence.: An organ that is part of the lymphatic system. The spleen produces lymphocytes, filters the blood, stores blood cells, and destroys old blood cells. It is located on the left side of the abdomen near the stomach.: Named locations of, or within, the body.
Lumbar spineLumbar spineThose vertebrae between the ribs and the pelvis, L1-L5 in man.
LungLungOne of a pair of viscera occupying the pulmonary cavities of the thorax, the organs of respiration in which aeration of the blood takes place. As a rule, the right lung is slightly larger than the left and is divided into three lobes (an upper, a middle, and a lower or basal), while the left has but two lobes (an upper and a lower or basal). Each lung is irregularly conical in shape, presenting a blunt upper extremity (the apex), a concave base following the curve of the diaphragm, an outer convex surface (costal surface), an inner or mediastinal surface (mediastinal surface), a thin and sharp anterior border, and a thick and rounded posterior border.
Lymph node(s)Lymph nodeA bean-shaped organ surrounded by a connective tissue capsule. It is part of the lymphatic system and is found throughout the body. It is composed predominantly of lymphocytes and its main function is immune protection.
Lymph Node(s) AxillaAxillary Lymph NodeOne of approximately 20-30 lymph nodes in chain formation that traverse the concavity of the underarm to the clavicle.
Lymph Node(s) CervicalCervical Lymph NodeAny of the lymph nodes located in the neck.
Lymph node(s) DistantDistant Lymph NodeFar apart in space, time, or relevance from a point of reference.: A rounded mass of lymphatic tissue that is surrounded by a capsule of connective tissue. Lymph glands filter lymph (lymphatic fluid), and they store lymphocytes (white blood cells). They are located along lymphatic vessels. Also called a lymph node.
Lymph Node(s) EpitrochlearEpitrochlear Lymph NodeA lymph node located above and adjacent to the elbow.
Lymph Node(s) FemoralFemoral Lymph NodeA lymph node located in the upper inner portion of the thigh.
Lymph Node(s) HilarHilar Lymph NodeA lymph node located in the hilum of the lung.
Lymph Node(s) IliacIliac Lymph NodeOne of the three lymph nodes of the pelvis: the superior gluteal, interior gluteal or sacral.
Lymph Node(s) Iliac-commonCommon Iliac Lymph NodeWidely known or encountered.: One of the three lymph nodes of the pelvis: the superior gluteal, interior gluteal or sacral.
Lymph Node(s) Iliac-externalExternal Iliac Lymph NodeA lymph node located along the external iliac artery.
Lymph Node(s) InguinalInguinal Lymph NodeA superficial or deep lymph node located in the inguinal area.
Lymph Node(s) Int MammaryInternal Mammary Lymph NodeAny of the lymph nodes of the breast located under the ribcage, near the sternum.
Lymph Node(s) MammaryMammary Lymph NodeHaving to do with the breast.: A bean-shaped organ surrounded by a connective tissue capsule. It is part of the lymphatic system and is found throughout the body. It is composed predominantly of lymphocytes and its main function is immune protection.
Lymph Node(s) MediastinalMediastinal Lymph NodeA lymph node located in the mediastinum. Mediastinal lymph nodes are arranged in three groups, one on the lateral, another on the medial, and a third on the anterior aspect of the vessels; the third group is, however, sometimes absent.
Lymph Node(s) MesentericMesenteric Lymph NodeA lymph node located in the mesentery.
Lymph Node(s) OccipitalOccipital Lymph NodeA lymph node located in the back of the head adjacent to the trapezius muscle.
Lymph node(s) Para aorticParaaortic Region Lymph NodeRegions near to the aorta.: A rounded mass of lymphatic tissue that is surrounded by a capsule of connective tissue. Lymph glands filter lymph (lymphatic fluid), and they store lymphocytes (white blood cells). They are located along lymphatic vessels. Also called a lymph node.
Lymph Node(s) ParacavalParacaval Lymph NodeExtending on all sides of simultaneously; encircling.: A large vein which returns blood from the head, neck and extremeties to the heart.: A bean-shaped organ surrounded by a connective tissue capsule. It is part of the lymphatic system and is found throughout the body. It is composed predominantly of lymphocytes and its main function is immune protection.
Lymph Node(s) ParotidParotid Gland Lymph NodeA lymph node located close to, on, or within the parotid gland. (NCI)
Lymph Node(s) PelvicPelvic Lymph NodeAny lymph node within the pelvic region.
Lymph Node(s) PeriportalPeriportal Lymph NodeExtending on all sides of simultaneously; encircling.: Of or pertaining to a porta, especially the porta of the liver; as, the portal vein, which enters the liver at the porta, and divides into capillaries after the manner of an artery. Portal is applied to other veins which break up into capillaries; as, the renal portal veins in the frog. (On-line Medical Dictionary): A bean-shaped organ surrounded by a connective tissue capsule. It is part of the lymphatic system and is found throughout the body. It is composed predominantly of lymphocytes and its main function is immune protection.
Lymph Node(s) PoplitealPopliteal Lymph NodeLymph node located within the fat layer of the knee joint.
Lymph node(s) RegionalRegional Lymph NodeRegional; limited to a particular location or area.: A rounded mass of lymphatic tissue that is surrounded by a capsule of connective tissue. Lymph glands filter lymph (lymphatic fluid), and they store lymphocytes (white blood cells). They are located along lymphatic vessels. Also called a lymph node.
Lymph Node(s) RetroperitonealRetroperitoneal Lymph NodeA lymph node located in the retroperitoneal space.
Lymph node(s) ScaleneScalene Lymph NodeA lymph node located in proximity to any of the scalene muscles.
Lymph Node(s) SplenicSplenic Lymph NodeA lymph node located in the hilar region of the spleen.
Lymph Node(s) SubclavicularInfraclavicular Lymph NodeA lymph node located in the area below the clavicle.
Lymph Node(s) SubmandibularSubmandibular Lymph NodeA lymph node located beneath the floor of the oral cavity.
Lymph Node(s) SupraclavSupraclavicular Lymph NodeA lymph node which is located above the clavicle.
LymphomaLymphomaA malignant (clonal) proliferation of B- lymphocytes or T- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites. This category includes Non-Hodgkin lymphomas and Hodgkin lymphomas.
Mammary GlandMammary GlandHaving to do with the breast.
MandibleMandibleThe largest and strongest bone of the FACE constituting the lower jaw. It supports the lower teeth.
MaxillaMaxillaThe upper jawbone in vertebrates: it is fused to the cranium.
Mediastinal Soft TissueMediastinal Soft TissueMediastinal; related to the mediastinum.: Refers to muscle, fat, fibrous tissue, blood vessels, or other supporting tissue of the body.
MediastinumMediastinumA group of organs surrounded by loose connective tissue, separating the two pleural sacs, between the sternum anteriorly and the vertebral column posteriorly as well as from the thoracic inlet superiorly to the diaphragm inferiorly. The mediastinum contains the heart and pericardium, the bases of the great vessels, the trachea and bronchi, esophagus, thymus, lymph nodes, thoracic duct, phrenic and vagus nerves, and other structures and tissues.
MesenteryMesenteryA double layer of peritoneum that attaches to the back wall of the abdominal cavity and supports the small intestines.
MesotheliumMesotheliumA simple layer of cells, derived from the mesoderm that lines the coelom or body cavity of the embryo. In the adult, it covers all true serous membranes (peritoneum, pericardium, pleura).
Mini MantleMinimantle Radiation FieldA radiation field that includes the bilateral cervical, supraclavicular, and axillary lymph nodes.
MouthOral CavityThe cavity lying at the upper end of the alimentary canal, bounded on the outside by the lips and inside by the oropharynx and containing in humans the tongue, gums, and teeth.
MuscleMuscleMuscle; one of the contractile organs of the body.
NailsNailThe cutaneous plate on the dorsal surface of the distal end of a finger or toe.
Nasal CavityNasal CavityThe proximal portion of the respiratory passages on either side of the nasal septum lying between the floor of the cranium and the roof of the mouth and extending from the face to the pharynx. The nasal cavity is lined with ciliated mucosa, extending from the nares to the pharynx.
Nasal Soft TissueNasal Soft TissueBy or having to do with the nose.: Refers to muscle, fat, fibrous tissue, blood vessels, or other supporting tissue of the body.
NasopharynxNasopharynxThe nasal part of the pharynx, lying above the level of the soft palate.
NeckNeckThe region that connects the head to the rest of the body.
Neck/ChestNeck and ChestThe region that connects the head to the rest of the body.: The part of the human body between the neck and the diaphragm or the corresponding part in other vertebrates.
Neck/Chest/Abdomen/PelvisNeck and Chest and Abdomen and PelvisThe region that connects the head to the rest of the body.: The part of the human body between the neck and the diaphragm or the corresponding part in other vertebrates.: The portion of the body that lies between the thorax and the pelvis.: The structure of the vertebrate skeleton supporting the lower limbs in humans and the hind limbs or corresponding parts in other vertebrates.: Named locations of, or within, the body.
NervenerveAny of the bundles of nerve fibers running to various organs and tissues of the body using chemical and electrical signals to transmit sensory and motor information from one body part to another.
Nerve(s) CranialCranial NerveAny of the 12 paired nerves that originate in the brain stem.
Not ApplicableNot ApplicableDetermination of a value is not relevant in the current context.
Ocular OrbitsOrbitThe bony cavity of the skull which contains the eye, anterior portion of the optic nerve, ocular muscles and ocular adnexa. Seven bones contribute to the structure of the orbit: the frontal, maxillary, zygomatic, sphenoid, lacrimal, ethmoid, and palatine bones.
OmentumOmentumA fold of peritoneum originating at the stomach and supporting the viscera.
Oral cavityOral CavityThe cavity lying at the upper end of the alimentary canal, bounded on the outside by the lips and inside by the oropharynx and containing in humans the tongue, gums, and teeth.
Oral Cavity, Mucosa onlyOral Cavity MucosaThe cavity lying at the upper end of the alimentary canal, bounded on the outside by the lips and inside by the oropharynx and containing in humans the tongue, gums, and teeth.: The moist tissue that lines some organs and body cavities (such as the nose, mouth, lungs) and makes mucus (a thick, slippery fluid).
OropharynxOropharynx(or-o-FAIR-inks) The middle part of the throat that includes the soft palate, the base of the tongue, and the tonsils.
OtherOtherDifferent than the one(s) previously specified or mentioned.
OvaryOvaryOne of the paired female reproductive glands containing the ova or germ cells; the ovary's stroma is a vascular connective tissue containing numbers of ovarian follicles enclosing the ova; surrounding this stroma is a more condensed layer of stroma called the tunica albuginea.
PA/LatPosterior Anterior Lateral ChestDenoting the back surface of the body; at or near the hind end in quadrupeds or toward the spine in primates.: Denoting the front surface of the body; often used to indicate the position of one structure relative to another.: Lateral; situated at or extending to the side.: The part of the human body between the neck and the diaphragm or the corresponding part in other vertebrates.
PalatePalate(PAL-et) The roof of the mouth. The front portion is bony (hard palate), and the back portion is muscular (soft palate).
PancreasPancreasA non-encapsulated elongated and lobulated organ, extending from the concavity of the duodenum to the spleen; it consists of a head, an elongated body, and a tail. It contains two functional components: an exocrine component that secretes juices into the intestine and an endocrine component that secretes hormones (insulin and glucagon).
Paraspinal GanglionSpinal GanglionSpinal; of or relating to the spine or spinal cord.: A cluster of nervous tissue principally composed of neuronal cell bodies external to the central nervous system (CNS).
ParathyroidParathyroid GlandOne of two small paired endocrine glands, superior and inferior, usually found embedded in the connective tissue capsule on the posterior surface of the thyroid gland; these glands secrete parathyroid hormone that regulates the metabolism of calcium and phosphorus. The parenchyma is composed of chief and oxyphilic cells arranged in anastomosing cords.
Parotid glandParotid GlandThe largest of the three paired salivary glands, located in front of the ear.
PatellaPatellaThe flat, triangular bone situated at the anterior part of the KNEE.
PelvisPelvisThe structure of the vertebrate skeleton supporting the lower limbs in humans and the hind limbs or corresponding parts in other vertebrates.
PenisPenisAn external male reproductive organ. It contains a tube called the urethra, which carries semen and urine to the outside of the body.
Peri-orbital Soft TissuePeriorbital Soft TissueOccurring in, or located in the area around the orbit of the eye.: Refers to muscle, fat, fibrous tissue, blood vessels, or other supporting tissue of the body.
PerianusAnal RegionThe area that includes the anus and the perianal skin.
PericardiumPericardiumA conical membranous sac filled with serous fluid in which the heart as well as the roots of the aorta and other large blood vessels are contained.
Peritoneal cavityPeritoneal CavityThe lower part of the abdomen that contains the intestines (the last part of the digestive tract), the stomach, and the liver. It is bound by thin membranes.
PeritoneumPeritoneum(PAIR-ih-toe-NEE-um) The tissue that lines the abdominal wall and covers most of the organs in the abdomen.
PharynxPharynx(FAIR-inks) The hollow tube about 5 inches long that starts behind the nose and ends at the top of the trachea (windpipe) and esophagus (the tube that goes to the stomach).
Pineal GlandPineal GlandA small endocrine gland in the brain, situated beneath the back part of the corpus callosum, that secretes melatonin.
Pituitary glandPituitary GlandA small, unpaired gland situated in the sella turcica tissue. It is connected to the hypothalamus by a short stalk.
PlacentaPlacentaAn organ present in some vertebrates during embryonic gestation that surrounds the fetus and provides it with nutrients and oxygen, facilitates gas and waste exchange between the fetus and mother, and provides parasitic cloaking from the mother's immune system by excretion of neurokinin B.
PleuraPleura(PLOOR-a) A thin layer of tissue covering the lungs and the wall of the chest cavity to protect and cushion the lungs. A small amount of fluid that acts as a lubricant allows the lungs to move smoothly in the chest cavity during breathing.
Popliteal fossaPopliteal FossaA diamond-shaped depression located in the back of the knee joint.
ProstateProstateA gland in the male reproductive system just below the bladder. It surrounds part of the urethra, the canal that empties the bladder. It produces a fluid that forms part of semen. (NCI-GLOSS)
PylorusPylorusThe lower part of the stomach that connects to the duodenum.
Rectosigmoid JunctionRectosigmoid RegionThe area where the sigmoid colon joins the rectum.
RectumRectumThe terminal portion of the gastrointestinal tract, extending from the rectosigmoid junction to the anal canal.
RetinaRetinaA light-sensitive membrane that lines the back wall of the eyeball. The retina is continuous with the optic nerve and this way transmits optical images to the brain.
Retro-orbital AreaRetro-Orbital RegionThe area of the body behind the orbit of the eye.
RetroperitoneumRetroperitoneumThe back of the abdomen where the kidneys lie and the great blood vessels run.
RibsRibsAny one of the paired bones, 12 on either side, extending from the thoracic vertebrae toward the median line on the ventral aspect of the trunk. The long curved bones which form the rib cage. Generally, ribs 1 to 7 are connected to the sternum' by their costal cartilages and are called true ribs, whereas ribs 8 to 12 are termed false ribs.
Round ligamentRound LigamentAny of the round ligaments including the round ligament of the liver and the round ligament of the uterus.
SacrumSacrumThe wedge-shaped bone consisting of five fused vertebrae, S1-S5 in man, forming the posterior part of the pelvis; its base connects with the lowest lumbar vertebra and its tip with the coccyx.
Salivary glandSalivary GlandAn exocrine gland that secretes saliva. Salivary glands are mostly located in and around the oral cavity.
ScalpScalpThe skin which covers the top of the head and which is usually covered by hair.
ScapulaScapulaThe flat triangle-shaped bone that connects the humerus with the clavicle in the back of the shoulder.
ScrotumScrotumThe musculocutaneous pouch that encloses the testicles. (NCI)
Seminal VesicleSeminal Vesicle(SEM-in-al VES-ih-kulz) Glands that help produce semen.
ShoulderShoulder JointThe region of the body between the neck and the upper arm.
Sigmoid colonSigmoid ColonThe portion of the colon that connects to the descending colon above and the rectum below.
Sinus(es)SinusA recess, cavity, or channel.
Sinus(es), MaxillaryMaxillary SinusA pyramidal-shaped, thin-walled, air-filled cavity located in the maxilla. It is lined by mucus membrane and periosteum (mucoperiosteum) which contains cilia. It is adjacent to the nasal cavity and communicates with the middle meatus of the nose. It is the largest paranasal sinus and is composed of three recesses: alveolar, zygomatic, and infraorbital.
Skeletal MuscleSkeletal Muscle TissueStriated muscles that are under voluntary control of the organism. They are connected at either or both ends to a bone and are utilized for locomotion and other movements. (NCI)
SkinSkinAn organ that constitutes the external surface of the body. It consists of the epidermis, dermis, and skin appendages.
SkullSkullThe skeleton of the head including the bones of the face and the bones enclosing the brain.
Small Bowel, Mucosa onlySmall Bowel MucosaThe portion of the digestive tube between the stomach and the cecum or beginning of the large intestine; it consists of three portions: duodenum, jejunum, and ileum. SYN intestinum tenue.: The moist tissue that lines some organs and body cavities (such as the nose, mouth, lungs) and makes mucus (a thick, slippery fluid).
Small intestineSmall IntestineThe portion of the digestive tube between the stomach and the cecum or beginning of the large intestine; it consists of three portions: duodenum, jejunum, and ileum. SYN intestinum tenue.
Soft TissueSoft tissueRefers to muscle, fat, fibrous tissue, blood vessels, or other supporting tissue of the body.
Spinal CordSpinal CordThe elongated, approximately cylindrical part of the central nervous system of vertebrates that lies in the vertebral canal and from which the spinal nerves emerge.|On-line Medical Dictionary
SpineVertebral ColumnThe spinal or vertebral column.
Spine/FemurVertebral Column and FemurThe spinal or vertebral column.: An article which expresses the relation of connection or addition. It is used to conjoin a word with a word, a clause with a clause, or a sentence with a sentence.: The longest and largest bone of the skeleton, it is situated between the hip and the knee.: Named locations of, or within, the body.
Spine/Femur/RadiusVertebral Column and Femur RadiusThe spinal or vertebral column.: An article which expresses the relation of connection or addition. It is used to conjoin a word with a word, a clause with a clause, or a sentence with a sentence.: The longest and largest bone of the skeleton, it is situated between the hip and the knee.: A straight line from the center to the perimeter of a circle or from the center to the surface of a sphere.
SpleenSpleenAn organ that produces lymphocytes, filters the blood, stores blood cells, and destroys those that are aging. It is located on the left side of the abdomen near the stomach. (OCC)
Splenic FlexureSplenic FlexureThe bend at the junction of the transverse and descending colon.
SternumSternumThe long, flat bone connecting with the cartilages of the first seven ribs and the clavicle.
StomachStomachThe organ located between the esophagus and the small intestine where digestion of food occurs before passing to the small intestine.
Stomach, Mucosa onlyStomach MucosaThe organ located between the esophagus and the small intestine where digestion of food occurs before passing to the small intestine.: The moist tissue that lines some organs and body cavities (such as the nose, mouth, lungs) and makes mucus (a thick, slippery fluid).
Subcutaneous tissueSubcutaneous TissueBeneath the skin.: An anatomical structure consisting of similarly specialized cells and intercellular matrix, aggregated according to genetically determined spatial relationships, performing a specific function.
SynoviumSynovial MembraneThe inner layer of the connective tissue that seals the joint.
SystemicSystemic(sis-TEM-ik) Affecting the entire body.
TendonTendonA band of fibrous connective tissue that joins bone to muscle.
TesticleTesticleEither of the paired male reproductive glands that produce the male germ cells and the male hormones.
ThighThighA part of the lower limb, located between hip and knee.
Thoracic spineThoracic spineThose vertebrae of the thoracic region, T1-T12 in man.
Thoracic/Lumbar spineThoracic And Lumbar Spine(thor-ASS-ik) Having to do with the chest.: An article which expresses the relation of connection or addition. It is used to conjoin a word with a word, a clause with a clause, or a sentence with a sentence.: Those vertebrae between the ribs and the pelvis, L1-L5 in man.
ThoraxThoraxThe upper part of the trunk between the neck and the abdomen. It contains the chief organs of the circulatory and respiratory systems. (From Stedman, 25th ed)
ThroatThroatThe narrow passage from the mouth to the cavity at the back of the mouth.
ThymusThymusAn organ that is part of the lymphatic system, in which T lymphocytes grow and multiply. The thymus is in the chest behind the breastbone.
Thyroid glandThyroid Gland(THIGH-royd) A gland located beneath the voice box (larynx) that produces thyroid hormone. The thyroid helps regulate growth and metabolism.
TibiaTibiaThe second longest bone of the skeleton. It is located on the medial side of the lower leg, articulating with the FIBULA laterally, the TALUS distally, and the FEMUR proximally.
TongueTongueThe muscular organ located in the floor of the mouth and serving as the principal organ of taste and modification of the voice in speech.
Tongue, Base of tongueBase of the TongueThe posterior one third of the tongue behind the terminal sulcus that forms the anterior aspect of the oro-pharynx responsible for swallowing and modification of the voice in speech.
TonsilTonsilSmall masses of lymphoid tissue on either side of the throat.
Tonsil, PharyngealTonsillar TissueA fold of lymphatic tissue covered by ciliated epithelium at the very back of the nose, in the roof of the nasopharynx.
TracheaTracheaThe fibrocartilaginous, mucous-lined tube passing from the larynx to the bronchi.
Trachea/Major BronchiTrachea and Main BronchusThe cartilaginous and membranous tube descending from the larynx and branching into the right and left main bronchi.: The left and right main bronchi considered as a group.
Transverse ColonTransverse ColonThe third division of the colon (large intestine). It communicates with the ascending colon in the upper right-hand quadrant of the abdomen and the descending colon in the upper left-hand quadrant.
TrunkTrunkThe body excluding the head and neck and limbs.
Trunk, SuperficialSuperficial TrunkOf little substance or significance; involving only a surface.: The body excluding the head and neck and limbs.
Umbilical CordUmbilical CordExtraembryonic structure that connects the fetus to the placenta. It contains two arteries and one vein.
UnknownUnknownNot known, not observed, not recorded, or refused.
Upper extremityUpper ExtremityThe region of the body that includes the arm, the forearm, and hand.
UreterUreterThe thick-walled tube that carries urine from each kidney to the bladder.
UrethraUrethra(yoo-REE-thra) The tube through which urine leaves the body. It empties urine from the bladder.
Urinary tractUrinary SystemThe organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra.
UterusUterusA hollow, thick-walled, muscular organ located within the pelvic cavity of a woman. Within the uterus the fertilized egg implants and the fetus develops during pregnancy.
UvulaUvulaThe fleshy lobe that hangs at the back of the soft palate.
VaginaVaginaThe female genital canal, extending from the uterus to the vulva.
Vas DeferensVas DeferensDuct carrying spermatozoa.
VeinVeinA blood vessel that carries blood toward the heart.
Vena Cava, Inferior/SuperiorVena CavaA large vein which returns blood from the head, neck and extremities to the heart.
VertebraVertebraAny of the ring-shaped bony structures that constitute the spinal column and surround the spinal cord.
Vertebral columnVertebral ColumnThe spinal or vertebral column.
VulvaVulvaThe external, visible part of the female genitalia surrounding the urethral and vaginal opening. The vulva includes the clitoris and inner as well as outer labia.
Whole bodyBodyThe entire physical structure of an organism. It is composed of anatomic systems, regions, cavities, and spaces.
WristWristA joint between the distal end of the radius and the proximal row of carpal bones. (NCI)
Optional Diagnosis Metastasis QuestionsThere is no requirement for inclusion of these elements on the case report form. If the design and scientific questions posed in the study dictate the need to collect this type of data, these elements should be included.
Lesions consistent with metastatic diseaseMetastasis Assessment Yes No Not Evaluable Indicator36824811.0CHARACTER
NoNoThe non-affirmative response to a question.
Not evaluableUnevaluableUnable to be evaluated.
YesYesThe affirmative response to a question or activity.