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Long NameStaging, Colon and Rectum NCI Standard Template
DefinitionThe collection of CDEs used in the colorectal staging module based on AJCC Edition 7.
ContextcaBIG
Protocol Long NameNCI Standard Template Forms
WorkflowRELEASED
TypeCRF
Public ID3443381
Version1.0
Module Long NameModule InstructionsQuestionCDECDE Public IDCDE VersionQuestion InstructionsValue Domain Data TypeValue Domain Unit of MeasureDisplay FormatValid ValueForm Value Meaning TextForm Value Meaning Desc.
Mandatory Colorectal Staging QuestionsThese items must be included when this data is collected for reporting.
Date Current Staging Assessment CompletedCurrent Stage Complete Assessment Date627393.0DATEMM/DD/YYYY
Conditional Colorectal Staging QuestionsThere are business rules to indicate situations under which this element should be used on a case report form.
Clinical T StageColorectal Cancer American Joint Committee on Cancer (AJCC) Edition 7 Clinical Tumor T Stage33575251.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
T0Colorectal Cancer pT0 TNM FindingColorectal cancer with no evidence of primary tumor. (from AJCC 6th and 7th Eds.)
T1Colorectal Cancer pT1 TNM FindingColorectal cancer with invasion into the submucosa. (from AJCC 6th and 7th Eds)
T2Colorectal Cancer pT2 TNM FindingColorectal cancer with invasion into the muscularis propria. (from AJCC 6th and 7th Eds.)
T3Colorectal Cancer pT3 TNM Finding v7Colorectal cancer with invasion through the muscularis propria into pericolorectal tissues. (from AJCC 7th Ed.)
T4aColorectal Cancer pT4a TNM Finding v7Colorectal cancer with penetration to the surface of the visceral peritoneum. (from AJCC 7th Ed.)
T4bColorectal Cancer pT4b TNM Finding v7Colorectal cancer with direct invasion or adherence to other organs or structures. (from AJCC 7th Ed.)
TisColorectal Cancer pTis TNM Finding v7Colorectal cancer with a finding of carcinoma in situ: intraepithelial or invasion of lamina propria. Note: Tis includes cancer cells confined within the glandular basement membrane (intraepithelial) or mucosal lamina propria (intramucosal) with no extension through the muscularis mucosae into the submucosa. (from AJCC 7th Ed.)
TXColorectal Cancer pTX TNM FindingColorectal cancer in which the primary tumor cannot be assessed. (from AJCC 6th and 7th Eds.)
Clinical N StageColorectal Cancer American Joint Committee on Cancer (AJCC) Edition 7 Clinical Regional Lymph Node N Stage33575271.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
N0Colorectal Cancer pN0 TNM FindingColorectal cancer without regional lymph node metastasis. (from AJCC 6th and 7th Eds.)
N1Colorectal Cancer pN1 TNM Finding v7Colorectal cancer with metastasis in 1-3 regional lymph nodes. (from AJCC 7th Ed.)
N1aColorectal Cancer pN1a TNM Finding v7Colorectal cancer with metastasis in one regional lymph node. (from AJCC 7th Ed.)
N1bColorectal Cancer pN1b TNM Finding v7Colorectal cancer with metastasis in 2-3 regional lymph nodes. (from AJCC 7th Ed.)
N1cColorectal Cancer pN1c TNM Finding v7Colorectal cancer with tumor deposit(s) in the subserosa, mesentery, or nonperitonealized pericolic or perirectal tissues without regional lymph node metastasis. (from AJCC 7th Ed.)
N2Colorectal Cancer pN2 TNM Finding v7Colorectal cancer with metastasis in four or more regional lymph nodes. (from AJCC 7th Ed.)
N2aColorectal Cancer pN2a TNM Finding v7Colorectal cancer with metastasis in 4-6 regional lymph nodes. (from AJCC 7th Ed.)
N2bColorectal Cancer pN2b TNM Finding v7Colorectal cancer with metastasis in seven or more regional lymph nodes. (from AJCC 7th Ed.)
NXColorectal Cancer pNX TNM FindingColorectal cancer in which the regional lymph nodes cannot be assessed. (from AJCC 6th and 7th Eds.)
Clinical M StageColorectal Cancer American Joint Committee on Cancer (AJCC) Edition 7 Clinical Distant Metastasis M Stage33575291.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
M0Colorectal Cancer cM0 TNM Finding v7Colorectal cancer without evidence of distant metastasis. (from AJCC 7th Ed.)
M1Colorectal Cancer cM1 TNM Finding v7Colorectal cancer with distant metastasis. (from AJCC 7th Ed.)
M1aColorectal Cancer cM1a TNM Finding v7Colorectal cancer with metastasis confined to one organ or site (e.g., liver, lung, ovary, nonregional node). (from AJCC 7th Ed.)
M1bColorectal Cancer cM1b TNM Finding v7Colorectal cancer with metastases in more than one organ/site or the peritoneum. (from AJCC 7th Ed.)
Pathologic T StageColorectal Cancer American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Tumor T Stage33575261.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
T0Colorectal Cancer pT0 TNM FindingColorectal cancer with no evidence of primary tumor. (from AJCC 6th and 7th Eds.)
T1Colorectal Cancer pT1 TNM FindingColorectal cancer with invasion into the submucosa. (from AJCC 6th and 7th Eds)
T2Colorectal Cancer pT2 TNM FindingColorectal cancer with invasion into the muscularis propria. (from AJCC 6th and 7th Eds.)
T3Colorectal Cancer pT3 TNM Finding v7Colorectal cancer with invasion through the muscularis propria into pericolorectal tissues. (from AJCC 7th Ed.)
T4aColorectal Cancer pT4a TNM Finding v7Colorectal cancer with penetration to the surface of the visceral peritoneum. (from AJCC 7th Ed.)
T4bColorectal Cancer pT4b TNM Finding v7Colorectal cancer with direct invasion or adherence to other organs or structures. (from AJCC 7th Ed.)
TisColorectal Cancer pTis TNM Finding v7Colorectal cancer with a finding of carcinoma in situ: intraepithelial or invasion of lamina propria. Note: Tis includes cancer cells confined within the glandular basement membrane (intraepithelial) or mucosal lamina propria (intramucosal) with no extension through the muscularis mucosae into the submucosa. (from AJCC 7th Ed.)
TXColorectal Cancer pTX TNM FindingColorectal cancer in which the primary tumor cannot be assessed. (from AJCC 6th and 7th Eds.)
Pathologic N StageColorectal Cancer American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Regional Lymph Node N Stage33575281.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
N0Colorectal Cancer pN0 TNM FindingColorectal cancer without regional lymph node metastasis. (from AJCC 6th and 7th Eds.)
N1Colorectal Cancer pN1 TNM Finding v7Colorectal cancer with metastasis in 1-3 regional lymph nodes. (from AJCC 7th Ed.)
N1aColorectal Cancer pN1a TNM Finding v7Colorectal cancer with metastasis in one regional lymph node. (from AJCC 7th Ed.)
N1bColorectal Cancer pN1b TNM Finding v7Colorectal cancer with metastasis in 2-3 regional lymph nodes. (from AJCC 7th Ed.)
N1cColorectal Cancer pN1c TNM Finding v7Colorectal cancer with tumor deposit(s) in the subserosa, mesentery, or nonperitonealized pericolic or perirectal tissues without regional lymph node metastasis. (from AJCC 7th Ed.)
N2Colorectal Cancer pN2 TNM Finding v7Colorectal cancer with metastasis in four or more regional lymph nodes. (from AJCC 7th Ed.)
N2aColorectal Cancer pN2a TNM Finding v7Colorectal cancer with metastasis in 4-6 regional lymph nodes. (from AJCC 7th Ed.)
N2bColorectal Cancer pN2b TNM Finding v7Colorectal cancer with metastasis in seven or more regional lymph nodes. (from AJCC 7th Ed.)
NXColorectal Cancer pNX TNM FindingColorectal cancer in which the regional lymph nodes cannot be assessed. (from AJCC 6th and 7th Eds.)
Pathologic M StageColorectal Cancer American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Distant Metastasis M Stage33575301.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
M1Colorectal Cancer pM1 TNM FindingColorectal cancer with distant metastasis. (from AJCC 6th and 7th Eds.)
M1aColorectal Cancer pM1a TNM Finding v7Colorectal cancer with metastasis confined to one organ or site (e.g., liver, lung, ovary, nonregional node). (from AJCC 7th Ed.)
M1bColorectal Cancer pM1b TNM Finding v7Colorectal cancer with metastases in more than one organ/site or the peritoneum. (from AJCC 7th Ed.)
Disease StageColorectal Cancer American Joint Committee on Cancer (AJCC) Edition 7 Group Stage33575311.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
0Stage 0 Colorectal CancerStage 0 includes: Tis, N0, M0. Tis: Carcinoma in situ: intraepithelial or invasion of the lamina propria. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th and 7th eds.)
IStage I Colorectal CancerStage I includes: (T1, N0, M0); (T2, N0, M0). T1: Tumor invades submucosa. T2: Tumor invades muscularis propria. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th and 7th eds.)
IIAStage IIA Colorectal CancerStage IIA includes: T3, N0, M0. T3: Tumor invades through the muscularis propria into pericolorectal tissues. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)
IIBStage IIB Colorectal CancerStage IIB includes: T4a, N0, M0. T4a: Tumor penetrates to the surface of the visceral peritoneum. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)
IICStage IIC Colorectal CancerStage IIC includes: T4b, N0, M0. T4b: Tumor directly invades or is adherent to other organs or structures. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)
IIIAStage IIIA Colorectal CancerStage IIIA includes: (T1-T2, N1/N1c, M0); (T1, N2a, M0). T1: Tumor invades submucosa. T2: Tumor invades muscularis propria. N1: Metastasis in 1-3 regional lymph nodes. N1c: Tumor deposit(s) in the subserosa, mesentery, or nonperitonealized pericolic or perirectal tissues without regional lymph node metastasis. N2a: Metastasis in 4-6 regional lymph nodes. M0: No distant metastasis. (AJCC 7th ed.)
IIIBStage IIIB Colorectal CancerStage IIIB includes: (T3-T4a, N1/N1c, M0); (T2-T3, N2a, M0); (T1-T2, N2b, M0). T1: Tumor invades submucosa. T2: Tumor invades muscularis propria. T3: Tumor invades through the muscularis propria into pericolorectal tissues. T4a: Tumor penetrates to the surface of the visceral peritoneum. N1: Metastasis in 1-3 regional lymph nodes. N1c: Tumor deposit(s) in the subserosa, mesentery, or nonperitonealized pericolic or perirectal tissues without regional lymph node metastasis. N2a: Metastasis in 4-6 regional lymph nodes. N2b: Metastasis in seven or more regional lymph nodes. M0: No distant metastasis. (AJCC 7th ed.)
IIICStage IIIC Colorectal CancerStage IIIC includes: (T4a, N2a, M0); (T3-T4a, N2b, M0); (T4b, N1-N2, M0). T3: Tumor invades through the muscularis propria into pericolorectal tissues. T4a: Tumor penetrates to the surface of the visceral peritoneum. T4b: Tumor directly invades or is adherent to other organs or structures. N1: Metastasis in 1-3 regional lymph nodes. N2: Metastasis in four or more regional lymph nodes. N2a: Metastasis in 4-6 regional lymph nodes. N2b: Metastasis in seven or more regional lymph nodes. M0: No distant metastasis. (AJCC 7th ed.)
IVAStage IVA Colorectal CancerStage IVA includes: Any T, Any N, M1a. M1a: Metastasis confined to one organ or site (e.g., liver, lung, ovary, nonregional node). (AJCC 7th ed.)
IVBStage IVB Colorectal CancerStage IVB includes: Any T, Any N, M1b. M1b: Metastases in more than one organ/site or the peritoneum. (AJCC 7th ed.)
Stage unknownStage UnknownA finding indicating that the extent of organ/tissue involvement by a malignant neoplasm is not reported or not assessed.
Optional Colorectal Staging QuestionsThere is no requirement for inclusion of these elements on the case report form. If the design and scientific questions posed in the study dictate the need to collect this type of data, these elements should be included.
Staging Time PointDisease Staging Timepoint Name28473521.0CHARACTER
Current DiagnosisCurrent DiagnosisOccurring in or belonging to the present time.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
Initial DiagnosisFirst DiagnosisPreceding all others in time or space or degree.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
RestagingRestagingRepeat of staging assessment
Study EnrollmentClinical Study EnrollmentResearch conducted with human subjects or on material of human origin in which an investigator directly interacts with human subjects; includes development of new technologies, mechanism of human diseases, therapy, clinical trials, epidemiology, behavior and health services research. : Enrollment; to insert, register, or enter in a list, catalog, or roll. (Merriam-Webster Online)