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Long NameStaging, Corpus Uteri Carcinoma NCI Standard Template
DefinitionThe collection of CDEs used in the corpus uteri carcinoma and carcinosarcoma staging module based on AJCC Edition 7 and FIGO standards.
ContextcaBIG
Protocol Long NameNCI Standard Template Forms
WorkflowRELEASED
TypeCRF
Public ID3444622
Version2.0
Header InstructionCarcinosarcomas should be staged as carcinomas
Module Long NameModule InstructionsQuestionCDECDE Public IDCDE VersionQuestion InstructionsValue Domain Data TypeValue Domain Unit of MeasureDisplay FormatValid ValueForm Value Meaning TextForm Value Meaning Desc.
Mandatory Corpus Uteri Carcinoma Staging QuestionsThese items must be included when this data is collected for reporting.
Date Current Staging Assessment CompletedCurrent Stage Complete Assessment Date627393.0DATEMM/DD/YYYY
Conditional Corpus Uteri Carcinoma Staging QuestionsThere are business rules to indicate situations under which this element should be used on a case report form.
Clinical T StageUterine Cancer American Joint Committee on Cancer (AJCC) Edition 7 Clinical Tumor T Stage34446151.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
TXUterine Corpus Carcinoma pTX TNM Finding v7Uterine corpus carcinoma in which primary tumor cannot be assessed. (from AJCC 7th Ed.)
T0Uterine Corpus Carcinoma pT0 TNM Finding v7Uterine corpus carcinoma in which there is no evidence of a primary tumor. (from AJCC 7th Ed.)
TisUterine Corpus Carcinoma pTis TNM Finding v7Uterine corpus carcinoma with a finding of carcinoma in situ (preinvasive carcinoma). FIGO no longer includes Stage 0 (Tis). (from AJCC 7th Ed.)
T1Uterine Corpus Carcinoma pT1 TNM Finding v7Uterine corpus carcinoma with tumor confined to uterine corpus. (from AJCC 7th Ed.)
T1aUterine Corpus Carcinoma pT1a TNM Finding v7Uterine corpus carcinoma with tumor limited to endometrium or invading less than one-half of the myometrium. (from AJCC 7th Ed.)
T1bUterine Corpus Carcinoma pT1b TNM Finding v7Uterine corpus carcinoma with tumor invading one-half or more of the myometrium. (from AJCC 7th Ed.)
T2Uterine Corpus Carcinoma pT2 TNM Finding v7Uterine corpus carcinoma that invades stromal connective tissue of the cervix but does not extend beyond uterus. Endocervical glandular involvement only should be considered as Stage I and not as Stage II. (from AJCC 7th Ed.)
T3aUterine Corpus Carcinoma pT3a TNM Finding v7Uterine corpus carcinoma that involves serosa and/or adnexa (direct extension or metastasis). (from AJCC 7th Ed.)
T3bUterine Corpus Carcinoma pT3b TNM Finding v7Uterine corpus carcinoma that involves vagina or parametrial tissue. (from AJCC 7th Ed.)
T4Uterine Corpus Carcinoma pT4 TNM Finding v7Uterine corpus carcinoma that invades bladder mucosa and/or bowel mucosa (bullous edema is not sufficient to classify a tumor as T4). (from AJCC 7th Ed.)
Clinical N StageUterine Cancer American Joint Committee on Cancer (AJCC) Edition 7 Clinical Regional Lymph Node N Stage34446171.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
NXUterine Corpus Carcinoma pNX TNM Finding v7Uterine corpus carcinoma in which regional lymph nodes cannot be assessed. (from AJCC 7th Ed.)
N0Uterine Corpus Carcinoma pN0 TNM Finding v7Uterine corpus carcinoma with no evidence of regional lymph node metastasis. (from AJCC 7th Ed.)
N1Uterine Corpus Carcinoma pN1 TNM Finding v7Uterine corpus carcinoma with regional lymph node metastasis to pelvic lymph nodes. (from AJCC 7th Ed.)
N2Uterine Corpus Carcinoma pN2 TNM Finding v7Uterine corpus carcinoma with regional lymph node metastasis to para-aortic lymph nodes, with or without positive pelvic lymph nodes. (from AJCC 7th Ed.)
Clinical M StageUterine Cancer American Joint Committee on Cancer (AJCC) Edition 7 Clinical Distant Metastasis M Stage34446191.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
M0Uterine Corpus Carcinoma cM0 TNM Finding v7Uterine corpus carcinoma with no distant metastasis. (from AJCC 7th Ed.)
M1Uterine Corpus Carcinoma cM1 TNM Finding v7Uterine corpus carcinoma with distant metastasis (includes metastasis to inguinal lymph nodes intraperitoneal disease, or lung, liver, or bone. It excludes metastasis to para-aortic lymph nodes, vagina, pelvic serosa, or adnexa). (from AJCC 7th Ed.)
Pathologic T StageUterine Cancer American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Tumor T Stage34446161.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
TXUterine Corpus Carcinoma pTX TNM Finding v7Uterine corpus carcinoma in which primary tumor cannot be assessed. (from AJCC 7th Ed.)
T0Uterine Corpus Carcinoma pT0 TNM Finding v7Uterine corpus carcinoma in which there is no evidence of a primary tumor. (from AJCC 7th Ed.)
TisUterine Corpus Carcinoma pTis TNM Finding v7Uterine corpus carcinoma with a finding of carcinoma in situ (preinvasive carcinoma). FIGO no longer includes Stage 0 (Tis). (from AJCC 7th Ed.)
T1Uterine Corpus Carcinoma pT1 TNM Finding v7Uterine corpus carcinoma with tumor confined to uterine corpus. (from AJCC 7th Ed.)
T1aUterine Corpus Carcinoma pT1a TNM Finding v7Uterine corpus carcinoma with tumor limited to endometrium or invading less than one-half of the myometrium. (from AJCC 7th Ed.)
T1bUterine Corpus Carcinoma pT1b TNM Finding v7Uterine corpus carcinoma with tumor invading one-half or more of the myometrium. (from AJCC 7th Ed.)
T2Uterine Corpus Carcinoma pT2 TNM Finding v7Uterine corpus carcinoma that invades stromal connective tissue of the cervix but does not extend beyond uterus. Endocervical glandular involvement only should be considered as Stage I and not as Stage II. (from AJCC 7th Ed.)
T3aUterine Corpus Carcinoma pT3a TNM Finding v7Uterine corpus carcinoma that involves serosa and/or adnexa (direct extension or metastasis). (from AJCC 7th Ed.)
T3bUterine Corpus Carcinoma pT3b TNM Finding v7Uterine corpus carcinoma that involves vagina or parametrial tissue. (from AJCC 7th Ed.)
T4Uterine Corpus Carcinoma pT4 TNM Finding v7Uterine corpus carcinoma that invades bladder mucosa and/or bowel mucosa (bullous edema is not sufficient to classify a tumor as T4). (from AJCC 7th Ed.)
Pathologic N StageUterine Cancer American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Regional Lymph Node N Stage34446181.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
NXUterine Corpus Carcinoma pNX TNM Finding v7Uterine corpus carcinoma in which regional lymph nodes cannot be assessed. (from AJCC 7th Ed.)
N0Uterine Corpus Carcinoma pN0 TNM Finding v7Uterine corpus carcinoma with no evidence of regional lymph node metastasis. (from AJCC 7th Ed.)
N1Uterine Corpus Carcinoma pN1 TNM Finding v7Uterine corpus carcinoma with regional lymph node metastasis to pelvic lymph nodes. (from AJCC 7th Ed.)
N2Uterine Corpus Carcinoma pN2 TNM Finding v7Uterine corpus carcinoma with regional lymph node metastasis to para-aortic lymph nodes, with or without positive pelvic lymph nodes. (from AJCC 7th Ed.)
Pathologic M StageUterine Cancer American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Distant Metastasis M Stage34446201.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
M1Uterine Corpus Carcinoma pM1 TNM Finding v7Uterine corpus carcinoma with distant metastasis (includes metastasis to inguinal lymph nodes intraperitoneal disease, or lung, liver, or bone. It excludes metastasis to para-aortic lymph nodes, vagina, pelvic serosa, or adnexa). (from AJCC 7th Ed.)
Disease StageUterine Cancer American Joint Committee on Cancer (AJCC) Edition 7 Group Stage34446211.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
0Stage 0 Uterine Corpus CancerStage 0 includes: Tis, N0, M0. Tis: Carcinoma in situ. N0: No regional lymph node metastasis. M0: No distant metastasis. This staging applies to carcinomas and carcinosarcomas. FIGO no longer includes Stage 0 (Tis). (AJCC 7th ed.)
IStage I Uterine Corpus CancerStage I includes: I (T1, N0, M0); IA: (T1a, N0, M0); IB (T1b, N0, M0). T1: Tumor confined to corpus uteri. T1a: Tumor limited to the endometrium or invades less than one-half of the myometrium. T1b: Tumor invades one-half or more of the myometrium. N0: No regional lymph node metastasis. M0: No distant metastasis. This staging applies to carcinomas and carcinosarcomas. (AJCC 7th ed.)
IAStage IA Uterine Corpus CancerStage IA includes: T1a, N0, M0. T1a: Tumor limited to the endometrium or invades less than one-half of the myometrium. N0: No regional lymph node metastasis. M0: No distant metastasis. This staging applies to carcinomas and carcinosarcomas. (AJCC 7th ed.)
IBStage IB Uterine Corpus CancerStage IB includes: T1b, N0, M0. T1b: Tumor invades one-half or more of the myometrium. N0: No regional lymph node metastasis. M0: No distant metastasis. This staging applies to carcinomas and carcinosarcomas. (AJCC 7th ed.)
IIStage II Uterine Corpus CancerStage II includes: T2, N0, M0. T2: Tumor invades stromal connective tissue of the cervix but does not extend beyond uterus. Endocervical glandular involvement only should be considered as Stage I and not as Stage II. N0: No regional lymph node metastasis. M0: No distant metastasis. This staging applies to carcinomas and carcinosarcomas. (AJCC 7th ed.)
IIIStage III Uterine Corpus CancerStage III includes: III (T3, N0, M0); IIIA (T3a, N0, M0); IIIB (T3b, N0, M0); IIIC (T1-T3, N1/N2, M0); IIIC1 (T1-T3, N1, M0); IIIC2 (T1-T3, N2, M0). T3: Tumor involves serosa and/or adnexa, vagina, or parametrial tissue. T3a: Tumor involves serosa and/or adnexa (direct extension or metastasis). T3b: Tumor involves vagina (direct extension or metastasis) or parametrial tissue. N0: No regional lymph node metastasis. N1: Regional lymph node metastasis to pelvic lymph nodes. N2: Regional lymph node metastasis to para-aortic lymph nodes, with or without positive pelvic lymph nodes. M0: No distant metastasis. This staging applies to carcinomas and carcinosarcomas. (AJCC 7th ed.)
IIIAStage IIIA Uterine Corpus CancerStage IIIA includes: T3a, N0, M0. T3a: Tumor involves serosa and/or adnexa (direct extension or metastasis). N0: No regional lymph node metastasis. M0: No distant metastasis. This staging applies to carcinomas and carcinosarcomas. (AJCC 7th ed.)
IIIBStage IIIB Uterine Corpus CancerStage IIIB includes: T3b, N0, M0. T3b: Tumor involves vagina (direct extension or metastasis) or parametrial tissue. N0: No regional lymph node metastasis. M0: No distant metastasis. This staging applies to carcinomas and carcinosarcomas. (AJCC 7th ed.)
IIIC1Stage IIIC1 Uterine Corpus CancerStage IIIC1 includes: T1-T3, N1, M0. T1: Tumor confined to corpus uteri. T2: Tumor invades stromal connective tissue of the cervix but does not extend beyond uterus. T3: Tumor involves serosa and/or adnexa, vagina, or parametrial tissue. N1: Regional lymph node metastasis to pelvic lymph nodes. M0: No distant metastasis. This staging applies to carcinomas and carcinosarcomas. (AJCC 7th ed.)
IIIC2Stage IIIC2 Uterine Corpus CancerStage IIIC2 includes: T1-T3, N2, M0. T1: Tumor confined to corpus uteri. T2: Tumor invades stromal connective tissue of the cervix but does not extend beyond uterus. T3: Tumor involves serosa and/or adnexa, vagina, or parametrial tissue. N2: Regional lymph node metastasis to para-aortic lymph nodes, with or without positive pelvic lymph nodes. M0: No distant metastasis. This staging applies to carcinomas and carcinosarcomas. (AJCC 7th ed.)
IVAStage IVA Uterine Corpus CancerStage IVA includes: T4, Any N, M0. T4: Tumor invades bladder mucosa and/or bowel mucosa (bullous edema is not sufficient to classify a tumor as T4). M0: No distant metastasis. This staging applies to carcinomas and carcinosarcomas. (AJCC 7th ed.)
IVBStage IVB Uterine Corpus CancerStage IVB includes: Any T, Any N, M1. M1: Distant metastasis (includes metastasis to inguinal lymph nodes, intraperitoneal disease, or lung, liver, or bone. It excludes metastasis to para-aortic lymph nodes, vagina, pelvic serosa, or adnexa). This staging applies to carcinomas and carcinosarcomas. (AJCC 7th ed.)
Stage unknownStage UnknownA finding indicating that the extent of organ/tissue involvement by a malignant neoplasm is not reported or not assessed.
StageGynecologic Tumor Grouping FIGO 1988 Endometrial Carcinoma Stage31140741.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
IStage ITumor confined to the corpus uteri (according to FIGO 1988 Stage Description)
IAStage IATumor limited to the endometrium (according to FIGO 1988 Stage Description)
IBStage IBInvasion to less than half of the myometrium (according to FIGO 1988 Stage Description)
ICStage ICInvasion equal to or more than half of the myometrium (according to FIGO 1988 Stage Description)
IIStage IIThe tumor has involved the corpus and the cervix (according to FIGO 1988 Stage Description)
IIAStage IIAEndocervical glandular involvement only (according to FIGO 1988 Stage Description)
IIBStage IIBCervical stromal invasion (according to FIGO 1988 Stage Description)
IIIStage IIIThe tumor has extended outside the uterus but not outside the pelvis (according to FIGO 1988 Stage Description)
IIIAStage IIIATumor invades the serosa of the corpus uteri and/or adnexae and/or positive cytological findings (according to FIGO 1988 Stage Description)
IIIBStage IIIBVaginal metastases (according to FIGO 1988 Stage Description)
IIICStage IIICMetastases to pelvic and/or para-aortic lymph nodes (according to FIGO 1988 Stage Description)
IVStage IVTumor invades bladder and/or bowel mucosa, and/or distant metastases (according to FIGO 1988 Stage Description)
IVAStage IVATumor invasion of bladder and/or bowel mucosa (according to FIGO 1988 Stage Description)
IVBStage IVBDistant metastases, including intraabdominal metastasis and/or inguinal lymph nodes (according to FIGO 1988 Stage Description)
FIGO StageEndometrial Carcinoma FIGO 2009 Stage31083772.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
Stage IFIGO Stage IA FIGO stage term that applies to gynecologic cancers. For cervical cancer, it refers to invasive cancer that is confined to the cervix; for endometrial cancer, it refers to cancer confined to the corpus uteri with no or less than one-half myometrial invasion (IA) or invasion of one-half or more of the myometrium (IB).
Stage IAFIGO Stage IAA FIGO stage term that applies to gynecologic cancers. For cervical cancer, it refers to invasive cancer that is diagnosed microscopically only. The stromal invasion has a maximum depth of 5.00 mm and a horizontal spread of 7.00 mm or less; for endometrial cancer, it refers to cancer limited to endometrium or invades less than one-half of the myometrium.
Stage IBFIGO Stage IBA FIGO stage term that applies to gynecologic cancers. For cervical cancer, it refers to invasive cancer that is clinically visible and is confined to the cervix or it is diagnosed microscopically and the stromal invasion is more than 5.00 mm and the horizontal spread is more than 7.00 mm; for endometrial cancer, it refers to cancer that is confined to the uterine body and invades one-half or more of the myometrium.
Stage IIFIGO Stage IIA FIGO stage term that applies to gynecologic cancers. For cervical cancer, it refers to cancer that invades beyond the cervix, but not to the pelvic wall or lower third of the vagina; for endometrial cancer, it refers to cancer that invades the stromal connective tissue of the cervix, but it does not extend beyond the uterus.
Stage IIIFIGO Stage IIIA FIGO stage term that applies to gynecologic cancers. For cervical cancer, it refers to cancer that extends to the pelvic wall, and/or involves the lower third of vagina, and/or causes hydronephrosis or non-functioning kidney; for endometrial cancer, FIGO stage III is subdivided into stages IIIA and IIIB; in FIGO stage IIIA, there is involvement of the serosa and/or the adnexa; for FIGO stage IIIB, there is vaginal or parametrial involvement.
Stage IIIAFIGO Stage IIIAA FIGO stage term that applies to gynecologic cancers. For cervical cancer, it refers to cancer that involves the lower third of vagina and there is no extension to the pelvic wall; for endometrial cancer, it refers to cancer with involvement of the serosa and/or the adnexa.
Stage IIIBFIGO Stage IIIBA FIGO stage term that applies to gynecologic cancers. For cervical cancer, it refers to cancer that extends to the pelvic wall, and/or causes hydronephrosis or non-functioning kidney; for endometrial cancer, it refers to cancer with vaginal or parametrial involvement.
Stage IIIC1FIGO Stage IIIC1A FIGO stage term that applies to gynecologic cancers. There is no FIGO stage IIIC1 for cervical cancer; for endometrial cancer, it refers to regional metastasis to pelvic lymph nodes.
Stage IIIC2FIGO Stage IIIC2A FIGO stage term that applies to gynecologic cancers. There is no FIGO stage IIIC2 for cervical cancer; for endometrial cancer, it refers to regional metastasis to para-aortic lymph nodes with or without metastasis to pelvic lymph nodes.
Stage IVFIGO Stage IVA FIGO stage term that applies to gynecologic cancers. For cervical cancer, it refers to cancer that invades the mucosa of bladder or rectum, and/or extends beyond the true pelvis (FIGO stage IVA), or to cancer with distant metastases (FIGO stage IVB); for endometrial cancer, it refers to cancer that invades the bladder mucosa and/or the bowel mucosa (FIGO stage IVA), or to cancer with distant metastases (FIGO stage IVB).
Stage IVAFIGO Stage IVAA FIGO stage term that applies to gynecologic cancers. For cervical cancer, it refers to cancer that invades the mucosa of bladder or rectum, and/or extends beyond the true pelvis; for endometrial cancer, it refers to cancer that invades the bladder mucosa and/or the bowel mucosa.
Stage IVBFIGO Stage IVBA FIGO stage term that applies to gynecologic cancers. For cervical cancer, it refers to cancer with distant metastases, including peritoneal involvement, involvement of the supraclavicular or mediastinal lymph nodes, and metastases to the lung, bone, or liver; for endometrial cancer, it refers to cancer with distant metastases, including metastases to the inguinal lymph nodes, intraperitoneal involvement, or metastases to the lung, bone, or liver. Endometrial cancer metastases to the para-aortic lymph nodes, vagina, adnexa, or pelvic serosa are excluded from this stage.
Optional Corpus Uteri Carcinoma Staging QuestionsThere is no requirement for inclusion of these elements on the case report form. If the design and scientific questions posed in the study dictate the need to collect this type of data, these elements should be included.
Staging Time PointDisease Staging Timepoint Name28473521.0CHARACTER
Current DiagnosisCurrent DiagnosisOccurring in or belonging to the present time.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
Initial DiagnosisFirst DiagnosisPreceding all others in time or space or degree.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
RestagingRestagingRepeat of staging assessment
Study EnrollmentClinical Study EnrollmentResearch conducted with human subjects or on material of human origin in which an investigator directly interacts with human subjects; includes development of new technologies, mechanism of human diseases, therapy, clinical trials, epidemiology, behavior and health services research. : Enrollment; to insert, register, or enter in a list, catalog, or roll. (Merriam-Webster Online)