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Long NameStaging, Liver NCI Standard Template
DefinitionThe collection of CDEs used in the liver staging module based on AJCC Edition 7.
ContextcaBIG
Protocol Long NameNCI Standard Template Forms
WorkflowRELEASED
TypeCRF
Public ID3443558
Version1.0
Module Long NameModule InstructionsQuestionCDECDE Public IDCDE VersionQuestion InstructionsValue Domain Data TypeValue Domain Unit of MeasureDisplay FormatValid ValueForm Value Meaning TextForm Value Meaning Desc.
Mandatory Liver Staging QuestionsThese items must be included when this data is collected for reporting.
Date Current Staging Assessment CompletedCurrent Stage Complete Assessment Date627393.0DATEMM/DD/YYYY
Conditional Liver Staging QuestionsThere are business rules to indicate situations under which this element should be used on a case report form.
Clinical T StageLiver Cancer American Joint Committee on Cancer (AJCC) Edition 7 Clinical Tumor T Stage33772091.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
TXLiver Cancer pTX TNM Finding v7Liver cancer in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)
T0Liver Cancer pT0 TNM Finding v7Liver cancer with no evidence of a primary tumor. (from AJCC 7th Ed.)
T1Liver Cancer pT1 TNM Finding v7Liver cancer with solitary tumor without vascular invasion. (from AJCC 7th Ed.)
T2Liver Cancer pT2 TNM Finding v7Liver cancer with solitary tumor with vascular invasion or multiple tumors none more than 5 cm in greatest dimension. (from AJCC 7th Ed.)
T3aLiver Cancer pT3a TNM Finding v7Liver cancer with multiple tumors more than 5 cm in greatest dimension. (from AJCC 7th Ed.)
T3bLiver Cancer pT3b TNM Finding v7Liver cancer with single tumor or multiple tumors of any size involving a major branch of the portal vein or hepatic vein. (from AJCC 7th Ed.)
T4Liver Cancer pT4 TNM Finding v7Liver cancer with tumor(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum. (from AJCC 7th Ed.)
Clinical N StageLiver Cancer American Joint Committee on Cancer (AJCC) Edition 7 Clinical Regional Lymph Node N Stage33772101.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
NXLiver Cancer pNX TNM Finding v7Liver cancer in which regional lymph nodes cannot be assessed. (from AJCC 7th Ed.)
N0Liver Cancer pN0 TNM Finding v7Liver cancer with no regional lymph node metastasis. (from AJCC 7th Ed.)
N1Liver Cancer pN1 TNM Finding v7Liver cancer with regional lymph node metastasis. (from AJCC 7th Ed.)
Clinical M StageLiver Cancer American Joint Committee on Cancer (AJCC) Edition 7 Clinical Distant Metastasis M Stage33772111.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
M0Liver Cancer cM0 TNM Finding v7Liver cancer without evidence of distant metastasis. (from AJCC 7th Ed.)
M1Liver Cancer cM1 TNM Finding v7Liver cancer with distant metastasis. (from AJCC 7th Ed.)
Pathologic T StageLiver Cancer American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Tumor T Stage33772121.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
TXLiver Cancer pTX TNM Finding v7Liver cancer in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)
T0Liver Cancer pT0 TNM Finding v7Liver cancer with no evidence of a primary tumor. (from AJCC 7th Ed.)
T1Liver Cancer pT1 TNM Finding v7Liver cancer with solitary tumor without vascular invasion. (from AJCC 7th Ed.)
T2Liver Cancer pT2 TNM Finding v7Liver cancer with solitary tumor with vascular invasion or multiple tumors none more than 5 cm in greatest dimension. (from AJCC 7th Ed.)
T3aLiver Cancer pT3a TNM Finding v7Liver cancer with multiple tumors more than 5 cm in greatest dimension. (from AJCC 7th Ed.)
T3bLiver Cancer pT3b TNM Finding v7Liver cancer with single tumor or multiple tumors of any size involving a major branch of the portal vein or hepatic vein. (from AJCC 7th Ed.)
T4Liver Cancer pT4 TNM Finding v7Liver cancer with tumor(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum. (from AJCC 7th Ed.)
Pathologic N StageLiver Cancer American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Regional Lymph Node N Stage33772131.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
NXLiver Cancer pNX TNM Finding v7Liver cancer in which regional lymph nodes cannot be assessed. (from AJCC 7th Ed.)
N0Liver Cancer pN0 TNM Finding v7Liver cancer with no regional lymph node metastasis. (from AJCC 7th Ed.)
N1Liver Cancer pN1 TNM Finding v7Liver cancer with regional lymph node metastasis. (from AJCC 7th Ed.)
Pathologic M StageLiver Cancer American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Distant Metastasis M Stage33772141.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
M1Liver Cancer pM1 TNM Finding v7Liver cancer with distant metastasis. (from AJCC 7th Ed.)
Disease StageLiver Cancer American Joint Committee on Cancer (AJCC) Edition 7 Group Stage33772151.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
Stage IStage I Hepatocellular CarcinomaStage I includes: T1, N0, M0. T1: Solitary tumor without vascular invasion. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th and 7th eds.)
Stage IIStage II Hepatocellular CarcinomaStage II includes: T2, N0, M0. T2: Solitary tumor with vascular invasion or multiple tumors none more than 5 cm. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th and 7th eds.)
Stage IIIAStage IIIA Hepatocellular CarcinomaStage IIIA includes: T3a, N0, M0. T3a: Multiple tumors more than 5 cm. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)
Stage IIIBStage IIIB Hepatocellular CarcinomaStage IIIB includes: T3b, N0, M0. T3b: Single tumor or multiple tumors of any size involving a major branch of the portal vein or hepatic vein. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)
Stage IIICStage IIIC Hepatocellular CarcinomaStage IIIC includes: T4, N0, M0. T4: Tumors(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)
Stage IVAStage IVA Hepatocellular CarcinomaStage IVA includes: Any T, N1, M0. N1: Regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)
Stage IVBStage IVB Hepatocellular CarcinomaStage IVB includes: Any T, Any N, M1. M1: Distant metastasis. (AJCC 7th ed.)
Stage unknownStage UnknownA finding indicating that the extent of organ/tissue involvement by a malignant neoplasm is not reported or not assessed.
Optional Liver Staging QuestionsThere is no requirement for inclusion of these elements on the case report form. If the design and scientific questions posed in the study dictate the need to collect this type of data, these elements should be included.
Staging Time PointDisease Staging Timepoint Name28473521.0CHARACTER
Current DiagnosisCurrent DiagnosisOccurring in or belonging to the present time.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
Initial DiagnosisFirst DiagnosisPreceding all others in time or space or degree.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
RestagingRestagingRepeat of staging assessment
Study EnrollmentClinical Study EnrollmentResearch conducted with human subjects or on material of human origin in which an investigator directly interacts with human subjects; includes development of new technologies, mechanism of human diseases, therapy, clinical trials, epidemiology, behavior and health services research. : Enrollment; to insert, register, or enter in a list, catalog, or roll. (Merriam-Webster Online)