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Long NameStaging, Lung NCI Standard Template
DefinitionThe collection of CDEs used in the lung staging module based on AJCC Edition 7.
ContextcaBIG
Protocol Long NameNCI Standard Template Forms
WorkflowDRAFT NEW
TypeCRF
Public ID4568771
Version1.0
Module Long NameModule InstructionsQuestionCDECDE Public IDCDE VersionValue Domain Data TypeValue Domain Unit of MeasureDisplay FormatValid ValueForm Value Meaning TextForm Value Meaning Desc.
Mandatory Lung Staging QuestionsThese items must be included when this data is collected for reporting.
Date Current Staging Assessment CompletedCurrent Stage Complete Assessment Date627393.0DATEMM/DD/YYYY
Conditional Lung Staging QuestionsThere are business rules to indicate situations under which this element should be used on a case report form.
Clinical T StageLung Cancer American Joint Committee on Cancer (AJCC) Edition 7 Clinical Tumor T Stage37450111.0CHARACTER
T0Lung Cancer T0 TNM FindingLung cancer without any evidence of a primary tumor. (from AJCC 6th and 7th Eds.)
T1Lung Cancer T1 TNM Finding v7Lung cancer with a tumor size of 3 cm or less in greatest dimension, surrounded by lung or visceral pleura and without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus). The uncommon superficial tumor of any size with its invasive component limited to the bronchial wall, which may extend proximal to the main bronchus, is also classified as T1a. (from AJCC 7th Ed.)
T1aLung Cancer T1a TNM Finding v7Lung cancer with a tumor size of 2 cm or less n greatest dimension, surrounded by lung or visceral pleura and without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus). The uncommon superficial tumor of any size with its invasive component limited to the bronchial wall, which may extend proximal to the main bronchus, is also classified as T1a. (from AJCC 7th Ed.)
T1bLung Cancer T1b TNM Finding v7Lung cancer with a tumor size more than 2 cm but 3 cm or less in greatest dimension, surrounded by lung or visceral pleura and without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus). The uncommon superficial tumor of any size with its invasive component limited to the bronchial wall, which may extend proximal to the main bronchus, is also classified as T1a. (from AJCC 7th Ed.)
T2Lung Cancer T2 TNM Finding v7Lung cancer with a tumor size more than 3 cm but 7 cm or less or tumor with any of the following features (T2 tumors with these features are classified T2a if 5 cm or less): Involves main bronchus, 2 cm or more distal to the carina; Invades visceral pleura (PL1 or PL2); Associated with atelectasis or obstructive pneumonitis that extends to the hilar region but does not involve the entire lung. (from AJCC 7th Ed.)
T2aLung Cancer T2a TNM Finding v7Lung cancer with a tumor size more than 3 cm but 5 cm or less in greatest dimension. (from AJCC 7th Ed.)
T2bLung Cancer T2b TNM Finding v7Lung cancer with a tumor size more than 5 cm but 7 cm or less in greatest dimension. (from AJCC 7th Ed.)
T3Lung Cancer T3 TNM Finding v7Lung cancer with a tumor size more than 7 cm or one that directly invades any of the following: parietal pleural (PL3) chest wall (including superior sulcus tumors), diaphragm, phrenic nerve, mediastinal pleura, parietal pericardium; or tumor in the main bronchus (less than 2 cm distal to the carina but without involvement of the carina); or associated atelectasis or obstructive pneumonitis of the entire lung or separate tumor nodule(s) in the same lobe. (from AJCC 7th Ed.)
T4Lung Cancer T4 TNM Finding v7Lung cancer with a tumor of any size that invades any of the following: mediastinum, heart, great vessels, trachea, recurrent laryngeal nerve, esophagus, vertebral body, carina, and separate tumor nodule(s) in a different ipsilateral lobe. (from AJCC 7th Ed.)
TisLung Cancer Tis TNM FindingLung cancer with a finding of carcinoma in situ. (from AJCC 6th and 7th Eds.)
TXLung Cancer TX TNM FindingLung cancer in which the primary tumor cannot be assessed, or in which the diagnosis is confirmed by the presence of malignant cells in sputum or bronchial washings, but not visualized by imaging or bronchoscopy. (from AJCC 6th and 7th Eds.)
Clinical N StageLung Cancer American Joint Committee on Cancer (AJCC) Edition 7 Clinical Regional Lymph Node N Stage37450121.0CHARACTER
N0Lung Cancer N0 TNM FindingLung cancer with no evidence of metastasis to regional lymph nodes. (from AJCC 6th and 7th Eds.)
N1Lung Cancer N1 TNM Finding v7Lung cancer with metastasis in ipsilateral peribronchial and/or ipsilateral hilar lymph nodes and intrapulmonary lymph nodes, including involvement by direct extension. (from AJCC 7th Ed.)
N2Lung Cancer N2 TNM FindingLung cancer with metastasis to ipsilateral mediastinal and/or subcarinal lymph nodes. (from AJCC 6th and 7th Eds.)
N3Lung Cancer N3 TNM FindingLung cancer with metastasis to contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene, or supraclavicular lymph nodes. (from AJCC 6th and 7th Eds.)
NXLung Cancer NX TNM FindingLung cancer in which regional lymph nodes cannot be assessed. (from AJCC 6th and 7th Eds.)
Clinical M StageLung Cancer American Joint Committee on Cancer (AJCC) Edition 7 Clinical Distant Metastasis M Stage37450131.0CHARACTER
M0Gastric Cancer cM0 TNM Finding v7Gastric cancer without evidence of distant metastasis. (from AJCC 7th Ed.)
M1Gastric Cancer cM1 TNM Finding v7Gastric cancer with distant metastasis. (from AJCC 7th Ed.)
Pathologic T StageLung Cancer American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Tumor T Stage37450141.0CHARACTER
T0Lung Cancer T0 TNM FindingLung cancer without any evidence of a primary tumor. (from AJCC 6th and 7th Eds.)
T1Lung Cancer T1 TNM Finding v7Lung cancer with a tumor size of 3 cm or less in greatest dimension, surrounded by lung or visceral pleura and without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus). The uncommon superficial tumor of any size with its invasive component limited to the bronchial wall, which may extend proximal to the main bronchus, is also classified as T1a. (from AJCC 7th Ed.)
T1aLung Cancer T1a TNM Finding v7Lung cancer with a tumor size of 2 cm or less n greatest dimension, surrounded by lung or visceral pleura and without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus). The uncommon superficial tumor of any size with its invasive component limited to the bronchial wall, which may extend proximal to the main bronchus, is also classified as T1a. (from AJCC 7th Ed.)
T1bLung Cancer T1b TNM Finding v7Lung cancer with a tumor size more than 2 cm but 3 cm or less in greatest dimension, surrounded by lung or visceral pleura and without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus). The uncommon superficial tumor of any size with its invasive component limited to the bronchial wall, which may extend proximal to the main bronchus, is also classified as T1a. (from AJCC 7th Ed.)
T2Lung Cancer T2 TNM Finding v7Lung cancer with a tumor size more than 3 cm but 7 cm or less or tumor with any of the following features (T2 tumors with these features are classified T2a if 5 cm or less): Involves main bronchus, 2 cm or more distal to the carina; Invades visceral pleura (PL1 or PL2); Associated with atelectasis or obstructive pneumonitis that extends to the hilar region but does not involve the entire lung. (from AJCC 7th Ed.)
T2aLung Cancer T2a TNM Finding v7Lung cancer with a tumor size more than 3 cm but 5 cm or less in greatest dimension. (from AJCC 7th Ed.)
T2bLung Cancer T2b TNM Finding v7Lung cancer with a tumor size more than 5 cm but 7 cm or less in greatest dimension. (from AJCC 7th Ed.)
T3Lung Cancer T3 TNM Finding v7Lung cancer with a tumor size more than 7 cm or one that directly invades any of the following: parietal pleural (PL3) chest wall (including superior sulcus tumors), diaphragm, phrenic nerve, mediastinal pleura, parietal pericardium; or tumor in the main bronchus (less than 2 cm distal to the carina but without involvement of the carina); or associated atelectasis or obstructive pneumonitis of the entire lung or separate tumor nodule(s) in the same lobe. (from AJCC 7th Ed.)
T4Lung Cancer T4 TNM Finding v7Lung cancer with a tumor of any size that invades any of the following: mediastinum, heart, great vessels, trachea, recurrent laryngeal nerve, esophagus, vertebral body, carina, and separate tumor nodule(s) in a different ipsilateral lobe. (from AJCC 7th Ed.)
TisLung Cancer Tis TNM FindingLung cancer with a finding of carcinoma in situ. (from AJCC 6th and 7th Eds.)
TXLung Cancer TX TNM FindingLung cancer in which the primary tumor cannot be assessed, or in which the diagnosis is confirmed by the presence of malignant cells in sputum or bronchial washings, but not visualized by imaging or bronchoscopy. (from AJCC 6th and 7th Eds.)
Pathologic N StageLung Cancer American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Regional Lymph Node N Stage37450151.0CHARACTER
N0Lung Cancer N0 TNM FindingLung cancer with no evidence of metastasis to regional lymph nodes. (from AJCC 6th and 7th Eds.)
N1Lung Cancer N1 TNM Finding v7Lung cancer with metastasis in ipsilateral peribronchial and/or ipsilateral hilar lymph nodes and intrapulmonary lymph nodes, including involvement by direct extension. (from AJCC 7th Ed.)
N2Lung Cancer N2 TNM FindingLung cancer with metastasis to ipsilateral mediastinal and/or subcarinal lymph nodes. (from AJCC 6th and 7th Eds.)
N3Lung Cancer N3 TNM FindingLung cancer with metastasis to contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene, or supraclavicular lymph nodes. (from AJCC 6th and 7th Eds.)
NXLung Cancer NX TNM FindingLung cancer in which regional lymph nodes cannot be assessed. (from AJCC 6th and 7th Eds.)
Pathologic M StageLung Cancer American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Distant Metastasis M Stage37450161.0CHARACTER
M1Lung Cancer pM1 TNM Finding v7Lung cancer with distant metastasis. (from AJCC 7th Ed.)
M1aLung Cancer pM1a TNM Finding v7Lung cancer with separate tumor nodule(s) in a contralateral lobe; tumor with pleural nodules or malignant pleural (or pericardial) effusion. Most pleural (and pericardial) effusions with lung cancer are due to tumor. In a few patients, however, multiple cytopathologic examinations of pleural (or pericardial) fluid) are negative for tumor, and the fluid is nonbloody and is not an exudate. Where these elements and clinical judgment dictate that the effusion is not related to the tumor, the effusion should be excluded as a staging element and the patient should be classified as M0. (from AJCC 7th Ed.)
M1bLung Cancer pM1b TNM Finding v7Distant metastasis. (from AJCC 7th Ed.)
Disease StageNon-Small Cell Lung Cancer American Joint Committee on Cancer (AJCC) Edition 7 Group Stage37450171.0CHARACTER
0Stage 0 Non-Small Cell Lung CancerStage 0 includes: Tis, N0, M0. Tis: Carcinoma in situ. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th and 7th eds.)
IAStage IA Non-Small Cell Lung CarcinomaStage IA includes: (T1a, N0, M0); (T1b, N0, M0). T1a: Lung cancer with a tumor size of 2 cm or less in greatest dimension, surrounded by lung or visceral pleura and without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus). The uncommon superficial tumor of any size with its invasive component limited to the bronchial wall, which may extend proximal to the main bronchus, is also classified as T1a. T1b: Lung cancer with a tumor size more than 2 cm but 3 cm or less in greatest dimension, surrounded by lung or visceral pleura and without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus). N0: No regional lymph metastasis. M0: No distant metastasis. (AJCC 7th ed.)
IBStage IB Non-Small Cell Lung CarcinomaStage IB includes: T2a, N0, M0. T2a: Lung cancer with a tumor size more than 3 cm but 5 cm or less in greatest dimension. N0: No regional lymph metastasis. M0: No distant metastasis. (AJCC 7th ed.)
IIAStage IIA Non-Small Cell Lung CarcinomaStage IIA includes: (T2b, N0, M0); (T1a, N1, M0); (T1b, N1, M0); (T2a, N1, M0). T2b: Lung cancer with a tumor size more than 5 cm but 7 cm or less in greatest dimension. T1a: Lung cancer with a tumor size of 2 cm or less in greatest dimension, surrounded by lung or visceral pleura and without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus). The uncommon superficial tumor of any size with its invasive component limited to the bronchial wall, which may extend proximal to the main bronchus, is also classified as T1a. T1b: Lung cancer with a tumor size more than 2 cm but 3 cm or less in greatest dimension, surrounded by lung or visceral pleura and without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus). T2a: Lung cancer with a tumor size more than 3 cm but 5 cm or less in greatest dimension. N0: No regional lymph node metastasis. N1: Lung cancer with metastasis in ipsilateral peribronchial and/or ipsilateral hilar lymph nodes and intrapulmonary lymph nodes, including involvement by direct extension. M0: No distant metastasis. (AJCC 7th ed.)
IIBStage IIB Non-Small Cell Lung CarcinomaStage IIB includes: (T2b, N1, M0); (T3, N0, M0). T2b: Lung cancer with a tumor size more than 5 cm but 7 cm or less in greatest dimension. T3: Lung cancer with a tumor size more than 7 cm or one that directly invades any of the following: parietal pleural (PL3) chest wall (including superior sulcus tumors), diaphragm, phrenic nerve, mediastinal pleura, parietal pericardium; or tumor in the main bronchus (less than 2 cm distal to the carina but without involvement of the carina); or associated atelectasis or obstructive pneumonitis of the entire lung or separate tumor nodule(s) in the same lobe. N0: No regional lymph node metastasis. N1: Lung cancer with metastasis in ipsilateral peribronchial and/or ipsilateral hilar lymph nodes and intrapulmonary lymph nodes, including involvement by direct extension. M0: No distant metastasis. (AJCC 7th ed.)
IIIAStage IIIA Non-Small Cell Lung CancerStage IIIA includes: (T1a, N2, M0); (T1b, N2, M0); (T2a, N2, M0); (T2b, N2, M0); (T3, N1, M0); (T3, N2, M0); (T4, N0, M0); (T4, N1, M0). T4: Lung cancer with a tumor of any size that invades any of the following: mediastinum, heart, great vessels, trachea, recurrent laryngeal nerve, esophagus, vertebral body, carina, and separate tumor nodule(s) in a different ipsilateral lobe. N1: Lung cancer with metastasis in ipsilateral peribronchial and/or ipsilateral hilar lymph nodes and intrapulmonary lymph nodes, including involvement by direct extension. N2: Lung cancer with metastasis to ipsilateral mediastinal and/or subcarinal lymph nodes. M0: No distant metastasis. (AJCC 7th ed.)
IIIBStage IIIB Non-Small Cell Lung CancerStage IIIB includes: (T1a, N3, M0); (T1b, N3, M0); (T2a, N3, M0); (T2b, N3, M0); (T3, N3, M0); (T4, N2, M0); (T4, N3, M0). T4: Lung cancer with a tumor of any size that invades any of the following: mediastinum, heart, great vessels, trachea, recurrent laryngeal nerve, esophagus, vertebral body, carina, and separate tumor nodule(s) in a different ipsilateral lobe. N2: Lung cancer with metastasis to ipsilateral mediastinal and/or subcarinal lymph nodes. N3: Lung cancer with metastasis to contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene, or supraclavicular lymph nodes. M0: No distant metastasis. (AJCC 7th ed.)
IVStage IV Non-Small Cell Lung CancerStage IV includes: (Any T, Any N, M1a); (Any T, Any N, M1b). M1a: Lung cancer with separate tumor nodule(s) in a contralateral lobe; tumor with pleural nodules or malignant pleural (or pericardial) effusion. M1b: Distant metastasis. (AJCC 7th ed.)
OccultOccult Non-Small Cell Lung CarcinomaA non-small cell lung carcinoma detectable by sputum cytology only. The primary tumor is undetectable radiographically or during bronchoscopy; therefore, it can not be assessed. (NCI05)
Stage unknownStage UnknownA finding indicating that the extent of organ/tissue involvement by a malignant neoplasm is not reported or not assessed.
Optional Lung Staging QuestionsThere is no requirement for inclusion of these elements on the case report form. If the design and scientific questions posed in the study dictate the need to collect this type of data, these elements should be included.
Staging Time PointDisease Staging Timepoint Name28473521.0CHARACTER
Current DiagnosisCurrent DiagnosisOccurring in or belonging to the present time.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
Initial DiagnosisFirst DiagnosisPreceding all others in time or space or degree.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
RestagingRestagingRepeat of staging assessment
Study EnrollmentClinical Study EnrollmentResearch conducted with human subjects or on material of human origin in which an investigator directly interacts with human subjects; includes development of new technologies, mechanism of human diseases, therapy, clinical trials, epidemiology, behavior and health services research. : Enrollment; to insert, register, or enter in a list, catalog, or roll. (Merriam-Webster Online)