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Long NameStaging, Neuroendocrine Tumor NCI Standard Template
DefinitionThe collection of CDEs used in the neuroendocrine tumor staging module based on AJCC Edition 7.
ContextcaBIG
Protocol Long NameNCI Standard Template Forms
WorkflowRELEASED
TypeCRF
Public ID5022991
Version1.0
Module Long NameModule InstructionsQuestionCDECDE Public IDCDE VersionValue Domain Data TypeValue Domain Unit of MeasureDisplay FormatValid ValueForm Value Meaning TextForm Value Meaning Desc.
Mandatory Neuroendocrine Tumor Staging QuestionsThese items must be included when this data is collected for reporting.
Date Current Staging Assessment CompletedCurrent Stage Complete Assessment Date627393.0DATEMM/DD/YYYY
Conditional Neuroendocrine Tumor Staging QuestionsThere are business rules to indicate situations under which this element should be used on a case report form.
Clinical T StageStomach Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Clinical Tumor T Stage49862971.0CHARACTER
T0Gastric Neuroendocrine Tumor pT0 TNM Finding v7Gastric neuroendocrine tumor with no evidence of a primary tumor. (from AJCC 7th Ed.)
T1Gastric Neuroendocrine Tumor pT1 TNM Finding v7Gastric neuroendocrine tumor invading lamina propria or submucosa and is 1 cm or less in size. (from AJCC 7th Ed.)
T2Gastric Neuroendocrine Tumor pT2 TNM Finding v7Gastric neuroendocrine tumor invading muscularis propria or is more than 1 cm in size. (from AJCC 7th Ed.)
T3Gastric Neuroendocrine Tumor pT3 TNM Finding v7Gastric neuroendocrine tumor penetrating subserosa. (from AJCC 7th Ed.)
T4Gastric Neuroendocrine Tumor pT4 TNM Finding v7Gastric neuroendocrine tumor invading visceral peritoneum (serosa) or other organs or adjacent structures. (from AJCC 7th Ed.)
TisGastric Neuroendocrine Tumor pTis TNM Finding v7Gastric neuroendocrine tumor with a finding of carcinoma in situ/dysplasia (tumor size less than 0.5 mm), confined to mucosa. (from AJCC 7th Ed.)
TXGastric Neuroendocrine Tumor pTX TNM Finding v7Gastric neuroendocrine tumor in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)
Clinical N StageStomach Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Clinical Regional Lymph Node N Stage49862981.0CHARACTER
N0Gastric Neuroendocrine Tumor pN0 TNM Finding v7Gastric neuroendocrine tumor with no regional lymph node metastasis. (from AJCC 7th Ed.)
N1Gastric Neuroendocrine Tumor pN1 TNM Finding v7Gastric neuroendocrine tumor with regional lymph node metastasis. (from AJCC 7th Ed.)
NXGastric Neuroendocrine Tumor pNX TNM Finding v7Gastric neuroendocrine tumor in which regional lymph nodes cannot be assessed. (from AJCC 7th Ed.)
Clinical M StageStomach Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Clinical Distant Metastasis M Stage49863111.0CHARACTER
M0Gastric Neuroendocrine Tumor cM0 TNM Finding v7Gastric neuroendocrine tumor without evidence of distant metastasis. (from AJCC 7th Ed.)
M1Gastric Neuroendocrine Tumor cM1 TNM Finding v7Gastric neuroendocrine tumor with distant metastasis. (from AJCC 7th Ed.)
Pathologic T StageStomach Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Tumor T Stage49863121.0CHARACTER
T0Gastric Neuroendocrine Tumor pT0 TNM Finding v7Gastric neuroendocrine tumor with no evidence of a primary tumor. (from AJCC 7th Ed.)
T1Gastric Neuroendocrine Tumor pT1 TNM Finding v7Gastric neuroendocrine tumor invading lamina propria or submucosa and is 1 cm or less in size. (from AJCC 7th Ed.)
T2Gastric Neuroendocrine Tumor pT2 TNM Finding v7Gastric neuroendocrine tumor invading muscularis propria or is more than 1 cm in size. (from AJCC 7th Ed.)
T3Gastric Neuroendocrine Tumor pT3 TNM Finding v7Gastric neuroendocrine tumor penetrating subserosa. (from AJCC 7th Ed.)
T4Gastric Neuroendocrine Tumor pT4 TNM Finding v7Gastric neuroendocrine tumor invading visceral peritoneum (serosa) or other organs or adjacent structures. (from AJCC 7th Ed.)
TisGastric Neuroendocrine Tumor pTis TNM Finding v7Gastric neuroendocrine tumor with a finding of carcinoma in situ/dysplasia (tumor size less than 0.5 mm), confined to mucosa. (from AJCC 7th Ed.)
TXGastric Neuroendocrine Tumor pTX TNM Finding v7Gastric neuroendocrine tumor in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)
Pathologic N StageStomach Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Regional Lymph Node N Stage49863141.0CHARACTER
N0Gastric Neuroendocrine Tumor pN0 TNM Finding v7Gastric neuroendocrine tumor with no regional lymph node metastasis. (from AJCC 7th Ed.)
N1Gastric Neuroendocrine Tumor pN1 TNM Finding v7Gastric neuroendocrine tumor with regional lymph node metastasis. (from AJCC 7th Ed.)
NXGastric Neuroendocrine Tumor pNX TNM Finding v7Gastric neuroendocrine tumor in which regional lymph nodes cannot be assessed. (from AJCC 7th Ed.)
Pathologic M StageStomach Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Distant Metastasis M Stage49863151.0CHARACTER
M1Gastric Neuroendocrine Tumor pM1 TNM Finding v7Gastric neuroendocrine tumor with distant metastasis. (from AJCC 7th Ed.)
Clinical T StageDuodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Clinical Tumor T Stage49863231.0CHARACTER
T0Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pT0 TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor with no evidence of a primary tumor. (from AJCC 7th Ed.)
T1Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pT1 TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor invading lamina propria or submucosa and is 1 cm or less in size (small intestinal tumors); for ampullary tumors: tumor 1 cm or less. (from AJCC 7th Ed.)
T2Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pT2 TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor invading muscularis propria or is more than 1 cm in size (small intestinal tumors); for ampullary tumors: tumor more than 1 cm. (from AJCC 7th Ed.)
T3Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pT3 TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor invading through the muscularis propria into subserosal tissue without penetration of overlying serosa (jejunal or ileal tumors) or invading pancreas or retroperitoneum (ampullary or duodenal tumors) or into non-peritonealized tissues. (from AJCC 7th Ed.)
T4Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pT4 TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor invading visceral peritoneum (serosa) or invading other organs. (from AJCC 7th Ed.)
TXDuodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pTX TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)
Clinical N StageDuodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Clinical Regional Lymph Node N Stage49863241.0CHARACTER
N0Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pN0 TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor with no regional lymph node metastasis. (from AJCC 7th Ed.)
N1Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pN1 TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor with regional lymph node metastasis. (from AJCC 7th Ed.)
NXDuodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pNX TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor in which regional lymph nodes cannot be assessed. (from AJCC 7th Ed.)
Clinical M StageDuodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Clinical Distant Metastasis M Stage49863251.0CHARACTER
M0Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor cM0 TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor without evidence of distant metastasis. (from AJCC 7th Ed.)
M1Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor cM1 TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor with distant metastasis. (from AJCC 7th Ed.)
Pathologic T StageDuodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Tumor T Stage49863261.0CHARACTER
T0Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pT0 TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor with no evidence of a primary tumor. (from AJCC 7th Ed.)
T1Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pT1 TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor invading lamina propria or submucosa and is 1 cm or less in size (small intestinal tumors); for ampullary tumors: tumor 1 cm or less. (from AJCC 7th Ed.)
T2Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pT2 TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor invading muscularis propria or is more than 1 cm in size (small intestinal tumors); for ampullary tumors: tumor more than 1 cm. (from AJCC 7th Ed.)
T3Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pT3 TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor invading through the muscularis propria into subserosal tissue without penetration of overlying serosa (jejunal or ileal tumors) or invading pancreas or retroperitoneum (ampullary or duodenal tumors) or into non-peritonealized tissues. (from AJCC 7th Ed.)
T4Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pT4 TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor invading visceral peritoneum (serosa) or invading other organs. (from AJCC 7th Ed.)
TXDuodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pTX TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)
Pathologic N StageDuodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Regional Lymph Node N Stage49863501.0CHARACTER
N0Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pN0 TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor with no regional lymph node metastasis. (from AJCC 7th Ed.)
N1Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pN1 TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor with regional lymph node metastasis. (from AJCC 7th Ed.)
NXDuodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pNX TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor in which regional lymph nodes cannot be assessed. (from AJCC 7th Ed.)
Pathologic M StageDuodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Distant Metastasis M Stage49863511.0CHARACTER
M1Duodenum/Ampulla/Jejunum/Ileum Neuroendocrine Tumor pM1 TNM Finding v7Duodenum/ampulla/jejunum/ileum neuroendocrine tumor with distant metastasis. (from AJCC 7th Ed.)
Clinical T StageColon or Rectum Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Clinical Tumor T Stage49863521.0CHARACTER
T0Colon or Rectum Neuroendocrine Tumor pT0 TNM Finding v7Colon or rectum neuroendocrine tumor with no evidence of a primary tumor. (from AJCC 7th Ed.)
T1Colon or Rectum Neuroendocrine Tumor pT1 TNM Finding v7Colon or rectum neuroendocrine tumor invading lamina propria or submucosa and is 2 cm or less in size. (from AJCC 7th Ed.)
T1aColon or Rectum Neuroendocrine Tumor pT1a TNM Finding v7Colon or rectum neuroendocrine tumor invading lamina propria or submucosa and is less than 1 cm in greatest dimension. (from AJCC 7th Ed.)
T1bColon or Rectum Neuroendocrine Tumor pT1b TNM Finding v7Colon or rectum neuroendocrine tumor invading lamina propria or submucosa and is 1-2 cm in greatest dimension. (from AJCC 7th Ed.)
T2Colon or Rectum Neuroendocrine Tumor pT2 TNM Finding v7Colon or rectum neuroendocrine tumor invading muscularis propria or is more than 2 cm in size with invasion of lamina propria or submucosa. (from AJCC 7th Ed.)
T3Colon or Rectum Neuroendocrine Tumor pT3 TNM Finding v7Colon or rectum neuroendocrine tumor invading through the muscularis propria into the subserosa, or into non-peritonealized pericolic or perirectal tissues. (from AJCC 7th Ed.)
T4Colon or Rectum Neuroendocrine Tumor pT4 TNM Finding v7Colon or rectum neuroendocrine tumor invading peritoneum or other organs. (from AJCC 7th Ed.)
TXColon or Rectum Neuroendocrine Tumor pTX TNM Finding v7Colon or rectum neuroendocrine tumor in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)
Clinical N StageColon or Rectum Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Clinical Regional Lymph Node N Stage49863531.0CHARACTER
N0Colon or Rectum Neuroendocrine Tumor pN0 TNM Finding v7Colon or rectum neuroendocrine tumor with no regional lymph node metastasis. (from AJCC 7th Ed.)
N1Colon or Rectum Neuroendocrine Tumor pN1 TNM Finding v7Colon or rectum neuroendocrine tumor with regional lymph node metastasis. (from AJCC 7th Ed.)
NXColon or Rectum Neuroendocrine Tumor pNX TNM Finding v7Colon or rectum neuroendocrine tumor in which regional lymph nodes cannot be assessed. (from AJCC 7th Ed.)
Clinical M StageColon or Rectum Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Clinical Distant Metastasis M Stage49863541.0CHARACTER
M0Colon or Rectum Neuroendocrine Tumor cM0 TNM Finding v7Colon or rectum neuroendocrine tumor without evidence of distant metastasis. (from AJCC 7th Ed.)
M1Colon or Rectum Neuroendocrine Tumor cM1 TNM Finding v7Colon or rectum neuroendocrine tumor with distant metastasis. (from AJCC 7th Ed.)
Pathologic T StageColon or Rectum Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Tumor T Stage49863551.0CHARACTER
T0Colon or Rectum Neuroendocrine Tumor pT0 TNM Finding v7Colon or rectum neuroendocrine tumor with no evidence of a primary tumor. (from AJCC 7th Ed.)
T1Colon or Rectum Neuroendocrine Tumor pT1 TNM Finding v7Colon or rectum neuroendocrine tumor invading lamina propria or submucosa and is 2 cm or less in size. (from AJCC 7th Ed.)
T1aColon or Rectum Neuroendocrine Tumor pT1a TNM Finding v7Colon or rectum neuroendocrine tumor invading lamina propria or submucosa and is less than 1 cm in greatest dimension. (from AJCC 7th Ed.)
T1bColon or Rectum Neuroendocrine Tumor pT1b TNM Finding v7Colon or rectum neuroendocrine tumor invading lamina propria or submucosa and is 1-2 cm in greatest dimension. (from AJCC 7th Ed.)
T2Colon or Rectum Neuroendocrine Tumor pT2 TNM Finding v7Colon or rectum neuroendocrine tumor invading muscularis propria or is more than 2 cm in size with invasion of lamina propria or submucosa. (from AJCC 7th Ed.)
T3Colon or Rectum Neuroendocrine Tumor pT3 TNM Finding v7Colon or rectum neuroendocrine tumor invading through the muscularis propria into the subserosa, or into non-peritonealized pericolic or perirectal tissues. (from AJCC 7th Ed.)
T4Colon or Rectum Neuroendocrine Tumor pT4 TNM Finding v7Colon or rectum neuroendocrine tumor invading peritoneum or other organs. (from AJCC 7th Ed.)
TXColon or Rectum Neuroendocrine Tumor pTX TNM Finding v7Colon or rectum neuroendocrine tumor in which the primary tumor cannot be assessed. (from AJCC 7th Ed.)
Pathologic N StageColon or Rectum Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Regional Lymph Node N Stage49863561.0CHARACTER
N0Colon or Rectum Neuroendocrine Tumor pN0 TNM Finding v7Colon or rectum neuroendocrine tumor with no regional lymph node metastasis. (from AJCC 7th Ed.)
N1Colon or Rectum Neuroendocrine Tumor pN1 TNM Finding v7Colon or rectum neuroendocrine tumor with regional lymph node metastasis. (from AJCC 7th Ed.)
NXColon or Rectum Neuroendocrine Tumor pNX TNM Finding v7Colon or rectum neuroendocrine tumor in which regional lymph nodes cannot be assessed. (from AJCC 7th Ed.)
Pathologic M StageColon or Rectum Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Distant Metastasis M Stage49863571.0CHARACTER
N0Colon or Rectum Neuroendocrine Tumor pN0 TNM Finding v7Colon or rectum neuroendocrine tumor with no regional lymph node metastasis. (from AJCC 7th Ed.)
N1Colon or Rectum Neuroendocrine Tumor pN1 TNM Finding v7Colon or rectum neuroendocrine tumor with regional lymph node metastasis. (from AJCC 7th Ed.)
NXColon or Rectum Neuroendocrine Tumor pNX TNM Finding v7Colon or rectum neuroendocrine tumor in which regional lymph nodes cannot be assessed. (from AJCC 7th Ed.)
Disease StageDigestive System Neuroendocrine Tumor American Joint Committee on Cancer (AJCC) Edition 7 Group Stage49863581.0CHARACTER
0Stage 0 Digestive System Neuroendocrine NeoplasmStage 0 includes: Tis, N0, M0. Tis (applies only to stomach): Carcinoma in situ/dysplasia (tumor size less than 0.5 mm), confined to mucosa. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)
IStage I Digestive System Neuroendocrine NeoplasmStage I includes: T1, N0, M0. T1: Stomach: tumor invades lamina propria or submucosa and is 1 cm or less in size; duodenum /jejunum/ileum: tumor invades lamina propria or submucosa and is 1 cm or less in size; ampulla: tumor 1 cm or less; colon or rectum: tumor invades lamina propria or submucosa and is 2 cm or less. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)
IIAStage IIA Digestive System Neuroendocrine NeoplasmStage IIA includes: T2, N0, M0. T2: Stomach/ duodenum /jejunum/ileum: tumor invades muscularis propria or is more than 1 cm in size; ampulla: tumor is more than 1 cm in size; colon or rectum: tumor invades muscularis propria or is more than 2 cm in size with invasion of lamina propria or submucosa. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)
IIBStage IIB Digestive System Neuroendocrine NeoplasmStage IIB includes: T3, N0, M0. T3: Stomach: tumor penetrates subserosa; jejunum/ileum: tumor invades through the muscularis propria into subserosal tissue without penetration of overlying serosa or invades into non-peritonealized tissues; ampulla/duodenum: tumor invades pancreas or retroperitoneum or into non-peritonealized tissues; colon or rectum: tumor invades through the muscularis propria into the subserosa, or into non-peritonealized pericolic or perirectal tissues. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)
IIIAStage IIIA Digestive System Neuroendocrine NeoplasmStage IIIA includes: T4, N0, M0. T4: Stomach/duodenum/ampulla/jejunum/ileum: tumor invades visceral peritoneum (serosa) or invades other organs or adjacent structures; colon or rectum: tumor invades peritoneum or other organs. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)
IIIBStage IIIB Digestive System Neuroendocrine NeoplasmStage IIIB includes: Any T, N1, M0. N1: Regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.)
IVStage IV Digestive System Neuroendocrine NeoplasmStage IV includes: Any T, Any N, M1. M1: Distant metastasis. (AJCC 7th ed.)
Stage unknownStage UnknownA finding indicating that the extent of organ/tissue involvement by a malignant neoplasm is not reported or not assessed.
Optional Neuroendocrine Tumor Staging QuestionsThere is no requirement for inclusion of these elements on the case report form. If the design and scientific questions posed in the study dictate the need to collect this type of data, these elements should be included.
Staging Time PointDisease Staging Timepoint Name28473521.0CHARACTER
Current DiagnosisCurrent DiagnosisOccurring in or belonging to the present time.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
Initial DiagnosisFirst DiagnosisPreceding all others in time or space or degree.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
RestagingRestagingRepeat of staging assessment
Study EnrollmentClinical Study EnrollmentResearch conducted with human subjects or on material of human origin in which an investigator directly interacts with human subjects; includes development of new technologies, mechanism of human diseases, therapy, clinical trials, epidemiology, behavior and health services research. : Enrollment; to insert, register, or enter in a list, catalog, or roll. (Merriam-Webster Online)