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Long NameStaging, Urinary Bladder NCI Standard Template
DefinitionThe collection of CDEs used in the urinary bladder staging module based on AJCC Edition 7.
ContextcaBIG
Protocol Long NameNCI Standard Template Forms
WorkflowRELEASED
TypeCRF
Public ID3443067
Version2.0
Module Long NameModule InstructionsQuestionCDECDE Public IDCDE VersionQuestion InstructionsValue Domain Data TypeValue Domain Unit of MeasureDisplay FormatValid ValueForm Value Meaning TextForm Value Meaning Desc.
Mandatory Bladder Staging QuestionsThese items must be included when this data is collected for reporting.
Date Current Staging Assessment CompletedCurrent Stage Complete Assessment Date627393.0DATEMM/DD/YYYY
Conditional Bladder Staging QuestionsThere are business rules to indicate situations under which this element should be used on a case report form.
Clinical T StageBladder Cancer American Joint Committee on Cancer (AJCC) Edition 7 Clinical Tumor T Stage33618762.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
pT2aBladder Cancer pT2a TNM Finding v7Bladder cancer with tumor invading the superficial muscularis propria (inner half). (from AJCC 7th Ed.)
pT2bBladder Cancer pT2b TNM Finding v7Bladder cancer with tumor invading the deep muscularis propria (outer half). (from AJCC 7th Ed.)
pT3aBladder Cancer pT3a TNM FindingBladder cancer with microscopic invasion into the perivesical tissue. (from AJCC 6th and 7th Eds.)
pT3bBladder Cancer pT3b TNM FindingBladder cancer with tumor macroscopically invading the perivesical tissue (extravesical mass). (from AJCC 6th and 7th Eds.)
T0Bladder Cancer pT0 TNM FindingBladder cancer in which there is no evidence of a primary tumor. (from AJCC 6th and 7th Eds.)
T1Bladder Cancer pT1 TNM FindingBladder cancer with tumor invading subepithelial connective tissue. (from AJCC 6th and 7th Eds.)
T2Bladder Cancer pT2 TNM Finding v7Bladder cancer with tumor invading the muscularis propria. (from AJCC 7th Ed.)
T3Bladder Cancer pT3 TNM FindingBladder cancer with tumor invading the perivesical tissue. (from AJCC 6th Ed.)
T4Bladder Cancer pT4 TNM Finding v7Bladder cancer with tumor invading any of the following: prostatic stroma, seminal vesicles, uterus, vagina, pelvic wall, abdominal wall. (from AJCC 7th Ed.)
T4aBladder Cancer pT4a TNM Finding v7Bladder cancer with tumor invading prostatic stroma, uterus, vagina. (from AJCC 7th Ed.)
T4bBladder Cancer pT4b TNM FindingBladder cancer with tumor invading pelvic wall, abdominal wall. (from AJCC 6th and 7th Eds.)
TaBladder Cancer pTa TNM FindingBladder cancer with a finding of noninvasive papillary carcinoma. (from AJCC 6th and 7th Eds.)
TisBladder Cancer pTis TNM FindingBladder cancer with a finding of carcinoma in situ: 'flat tumor'. (from AJCC 6th and 7th Eds.)
TXBladder Cancer pTX TNM FindingBladder cancer in which the primary tumor cannot be assessed. (from AJCC 6th and 7th Eds.)
Clinical N StageBladder Cancer American Joint Committee on Cancer (AJCC) Edition 7 Clinical Regional Lymph Node N Stage33618771.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
NXBladder Cancer pNX TNM FindingBladder cancer in which the regional lymph nodes cannot be assessed. (from AJCC 6th and 7th Eds.)
N0Bladder Cancer pN0 TNM FindingBladder cancer in which there is no regional lymph node metastasis. (from AJCC 6th and 7th Eds.)
N1Bladder Cancer pN1 TNM Finding v7Bladder cancer with single regional lymph node metastasis in the true pelvis (hypogastric, obturator, external iliac, or presacral lymph node). (from AJCC 7th Ed.)
N2Bladder Cancer pN2 TNM Finding v7Bladder cancer with multiple regional lymph node metastases in the true pelvis (hypogastric, obturator, external iliac, or presacral lymph node metastasis). (from AJCC 7th Ed.)
N3Bladder Cancer pN3 TNM Finding v7Bladder cancer with metastasis to the common iliac lymph nodes. (from AJCC 7th Ed.)
Clinical M StageBladder Cancer American Joint Committee on Cancer (AJCC) Edition 7 Clinical Distant Metastasis M Stage33618791.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
M0Bladder Cancer cM0 TNM Finding v7Bladder cancer without evidence of distant metastasis. (from AJCC 7th Ed.)
M1Bladder Cancer cM1 TNM Finding v7Bladder cancer with distant metastasis. (from AJCC 7th Ed.)
Pathologic T StageBladder Cancer American Joint Committee On Cancer (AJCC) Edition 7 Pathologic Tumor T Stage33618802.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
pT2aBladder Cancer pT2a TNM Finding v7Bladder cancer with tumor invading the superficial muscularis propria (inner half). (from AJCC 7th Ed.)
pT2bBladder Cancer pT2b TNM Finding v7Bladder cancer with tumor invading the deep muscularis propria (outer half). (from AJCC 7th Ed.)
pT3aBladder Cancer pT3a TNM FindingBladder cancer with microscopic invasion into the perivesical tissue. (from AJCC 6th and 7th Eds.)
pT3bBladder Cancer pT3b TNM FindingBladder cancer with tumor macroscopically invading the perivesical tissue (extravesical mass). (from AJCC 6th and 7th Eds.)
T0Bladder Cancer pT0 TNM FindingBladder cancer in which there is no evidence of a primary tumor. (from AJCC 6th and 7th Eds.)
T1Bladder Cancer pT1 TNM FindingBladder cancer with tumor invading subepithelial connective tissue. (from AJCC 6th and 7th Eds.)
T2Bladder Cancer pT2 TNM Finding v7Bladder cancer with tumor invading the muscularis propria. (from AJCC 7th Ed.)
T3Bladder Cancer pT3 TNM FindingBladder cancer with tumor invading the perivesical tissue. (from AJCC 6th Ed.)
T4Bladder Cancer pT4 TNM Finding v7Bladder cancer with tumor invading any of the following: prostatic stroma, seminal vesicles, uterus, vagina, pelvic wall, abdominal wall. (from AJCC 7th Ed.)
T4aBladder Cancer pT4a TNM Finding v7Bladder cancer with tumor invading prostatic stroma, uterus, vagina. (from AJCC 7th Ed.)
T4bBladder Cancer pT4b TNM FindingBladder cancer with tumor invading pelvic wall, abdominal wall. (from AJCC 6th and 7th Eds.)
TaBladder Cancer pTa TNM FindingBladder cancer with a finding of noninvasive papillary carcinoma. (from AJCC 6th and 7th Eds.)
TisBladder Cancer pTis TNM FindingBladder cancer with a finding of carcinoma in situ: 'flat tumor'. (from AJCC 6th and 7th Eds.)
TXBladder Cancer pTX TNM FindingBladder cancer in which the primary tumor cannot be assessed. (from AJCC 6th and 7th Eds.)
Pathologic N StageBladder Cancer American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Regional Lymph Node N Stage33618831.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
NXBladder Cancer pNX TNM FindingBladder cancer in which the regional lymph nodes cannot be assessed. (from AJCC 6th and 7th Eds.)
N0Bladder Cancer pN0 TNM FindingBladder cancer in which there is no regional lymph node metastasis. (from AJCC 6th and 7th Eds.)
N1Bladder Cancer pN1 TNM Finding v7Bladder cancer with single regional lymph node metastasis in the true pelvis (hypogastric, obturator, external iliac, or presacral lymph node). (from AJCC 7th Ed.)
N2Bladder Cancer pN2 TNM Finding v7Bladder cancer with multiple regional lymph node metastases in the true pelvis (hypogastric, obturator, external iliac, or presacral lymph node metastasis). (from AJCC 7th Ed.)
N3Bladder Cancer pN3 TNM Finding v7Bladder cancer with metastasis to the common iliac lymph nodes. (from AJCC 7th Ed.)
Pathologic M StageBladder Cancer American Joint Committee on Cancer (AJCC) Edition 7 Pathologic Distant Metastasis M Stage33618841.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
M1Bladder Cancer pM1 TNM FindingBladder cancer with distant metastasis. (from AJCC 6th and 7th Eds.)
Disease StageBladder Cancer American Joint Committee on Cancer (AJCC) Edition 7 Group Stage33619031.0Conditionality Rule: Inclusion based on patient population being studied.CHARACTER
0aStage 0a Bladder Urothelial CarcinomaStage 0a includes: Ta, N0, M0. Ta: Papillary noninvasive carcinoma. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th and 7th eds.)
0isStage 0is Bladder Urothelial CarcinomaStage 0is includes: Tis, N0, M0. Tis: Carcinoma in situ: "flat tumor". N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th and 7th eds.)
IStage I Bladder CancerStage I includes: T1, N0, M0. T1: Tumor invades subepithelial connective tissue. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th and 7th eds.)
IIStage II Bladder CancerStage II includes: (T2a, N0, M0); (T2b, N0, M0). T2a: Tumor invades superficial muscle (inner half). T2b: Tumor invades deep muscle (outer half). N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th and 7th Eds.)
IIIStage III Bladder CancerStage III includes: (T3a, N0, M0); (T3b, N0, M0); (T4a, N0, M0). T3a: Tumor microscopically invades perivesical tissue. T3b: Tumor macroscopically invades perivesical tissue (extravesical mass). T4a: Tumor invades prostatic stroma, uterus, vagina. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th and 7th eds.)
IVStage IV Bladder CancerStage IV includes: (T4b, N0, M0); (Any T, N1-3, M0); (Any T, Any N, M1). T4b: Tumor invades pelvic wall, abdominal wall. N0: No regional lymph node metastasis. N1: Single regional lymph node metastasis in the true pelvis (hypogastric, obturator, external iliac, or presacral lymph node). N2: Multiple regional lymph node metastases in the true pelvis (hypogastric, obturator, external iliac, or presacral lymph node metastasis). N3: Metastasis to the common iliac lymph nodes. M0: No distant metastasis. M1: Distant metastasis. (AJCC 7th ed.)
Stage unknownStage UnknownA finding indicating that the extent of organ/tissue involvement by a malignant neoplasm is not reported or not assessed.
Optional Bladder Staging QuestionsThere is no requirement for inclusion of these elements on the case report form. If the design and scientific questions posed in the study dictate the need to collect this type of data, these elements should be included.
Staging Time PointDisease Staging Timepoint Name28473521.0CHARACTER
Current DiagnosisCurrent DiagnosisOccurring in or belonging to the present time.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
Initial DiagnosisFirst DiagnosisPreceding all others in time or space or degree.: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
RestagingRestagingRepeat of staging assessment
Study EnrollmentClinical Study EnrollmentResearch conducted with human subjects or on material of human origin in which an investigator directly interacts with human subjects; includes development of new technologies, mechanism of human diseases, therapy, clinical trials, epidemiology, behavior and health services research. : Enrollment; to insert, register, or enter in a list, catalog, or roll. (Merriam-Webster Online)