The following information are provided in this wiki:

Wiki Pages for Application Developers

This family of pages focuses on the software interfaces to the caDSR available to programmers/software developers. The pages include details on the caDSR API, XML messages produced and consumed by the caDSR products and the caDSR UML Model.

Start with Retrieving caDSR Content for an overview of the various methods to connect to the caDSR including APIs and HTTP interfaces.

caDSR Overview for Developers

The Cancer Data Standards Registry and Repository (caDSR) is database and a set of APIs and tools based on the ISO/IEC 11179 Information Technology Metadata Registries (MDR) standard. The caDSR provides the means to create, edit, control, and deploy data elements for metadata consumers.

Metadata is defined as "data about data" or "the description of a piece of information." Standardizing and registering metadata addresses a significant problem in biomedical data management: the wide variety of ways that similar data are collected and described.

The ISO/IEC 11179 standard defines a framework for how metadata can be specified, maintained in a consistent manner, shared, and used across diverse domains. The caDSR is a conforming implementation of the ISO/IEC 11179 metadata standard with NCI extensions. The caDSR has been designed to support creation, maintenance, registration, and use of metadata in accordance with the metadata standard; in addition, the NCI has extended the standard, most notably in the use of controlled terminology. This enables metadata consumers to register the descriptive information needed to render cancer research data reusable and interoperable.

The fundamental unit of data in the ISO/IEC 11179 standard is called a data element. According to the ISO metadata standard, any item represented by a data element has two distinct parts: an explicit definition that is independent of any particular implementation, and an explicit description of implementation--specific details regarding how the item is represented in computer storage. Capturing these two aspects makes it possible to compare data elements that describe the same thing across different applications, and to understand what data transformation may be necessary in order to make the data comparable.

caCORE-like systems follow an object-oriented paradigm where classes of data are described using UML models. A UML model, serialized into XMI, can then be used to transform the UML model objects into caDSR registered items. Once registered, the items in caDSR can be re-used in other systems' models. If different systems are using the same registered terms (metadata) for the data in their models, those systems can more easily communicate and share information.

The caDSR itself is a database that contains Administered Items. As defined in the ISO/IEC 11179 standard, an Administered Item is an item (a Data Element or one of the associated components that comprise a Data Element) for which administrative information must be recorded. caDSR administered items are supported by the use of externally defined terminologies and controlled vocabularies, such as the NCI Thesaurus.

To support the database, the caDSR also has a suite of tools for creating, sharing, and deploying data elements (also called common data elements or CDEs). These tools include a public CDE Browser that enables you to search for data elements, create forms, and download CDEs, and a UML Model Browser viewer that makes it easier to find CDEs that are registered as part of UML modeling projects. All of the caDSR tools and interfaces connect to the same central database. Links to further information regarding the caDSR tools appear in the section "caDSR Tools."

By complying with the ISO/IEC 11179 standard, caDSR provides, among other things, a semantic bridge between the data elements contained in registered data objects and standard vocabularies and ontologies. caDSR was originally designed to support the development and deployment of data elements as metadata descriptors for NCI-sponsored research, but now supports an ever-widening group of users and metadata consumers in caBIG®.