h2. Summary
In 2004 when presenting the ACRIN proposal to conduct the CTC trial to the NCI Executive Committee, a case was made that image data sharing, publicly accessible through an as yet to be developed NCI Image Archive (NCIA) would be a valuable research asset to a wide image processing research community. Adding to the many merits of that proposal, the data-sharing component was strongly endorsed. ACRIN completed the trial expeditiously and its results were published in NEJM in fall 2008 to wide interest. Please see their NEJM publication for their published results and the ACRIN website itself for a more complete protocol description ([http://www.acrin.org/TabID/151/Default.aspx]). ACRIN has graciously allowed the wider research community access to a portion of the data from that trial.
Thus [NCIA|http://imaging.nci.nih.gov] offers a limited set (827) of DICOM image cases for download, de-identified of private health information, with spreadsheets identifying positive and negative polyp cases. The collection is offered to provide the broad research community an ability to develop CAD algorithms for polyp detection. CTC strengthened by competitive CAD methods stands to offer an efficient public health tool for reducing the incidence of colon cancer.
The present "CT Colonography" (CTC) image collection, publicly downloadable in DICOM format at [https://imaging.nci.nih.gov/ncia/] contains 827 cases from the well conducted, optical colonoscopy (OC) validated, ACRIN clinical trial whose subjects underwent same-day sequential CTC followed by OC. The attached documents in this Wiki offer separate lists of those OC verified cases that contain: [Imaging:CT Colonography^NCIA CTC no polyp found.xls]; [69 cases possessing 6 to 9 mm polyps|Imaging:CT Colonography^NCIA CTC 6 to 9 mm polyps.xls]; and [35 cases that possess at least one polyp "larger than 10 mm."|Imaging:CT Colonography^NCIA CTC large 10 mm polyps.xls]
Notably, this collection, though a subset of the ACRIN 2600\+ total cases, nonetheless proportionally represents the incidence and prevalence of polyp found in the general population.
h2. Accrual Details
*Submission Software* \- Field Center & Clinical Trial Processor (CTP)
*De-identification* *Schema* \- \*insert da.script\*
*Collection Security* \- Publicly available to all registered users
*Collection status* \- Complete (827 cases)
*Modality types* \- CT
*Contact* *Sites* \- ACRIN
h2. Public Notification
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{color:blue}Carl{color}
The NCI "CT Colonography" (CTC) image collection, downloadable as DICOM studies at https://imaging.nci.nih.gov/ncia/ has now been enlarged to a total of 827 cases {color:black}acquired{color}from the optical{color:navy}l{color}y (OC)-validated ACRIN CTC trial in which subjects underwent same-day CTC and OC. A description of the collection can be found at:
https://wiki.nci.nih.gov/download/attachments/13502514/NCIA+CTC+collection+explained.doc A key to the OC validation tables can be found at:
https://wiki.nci.nih.gov/download/attachments/13502514/Polyp+description+key+table.tiff Three polyp{color:navy}\-{color}size-grouped case lists can be found a{color:navy}s{color}:
'{color:navy}N{color}o polyp found' (243 cases);
https://wiki.nci.nih.gov/download/attachments/13502514/NCIA+CTC+no+polyp+found.xls 6 to 9 mm polyps (69 cases);
https://wiki.nci.nih.gov/download/attachments/13502514/NCIA+CTC+6+to+9+mm+polyps.xls and "larger than 10 mm" (35 cases) https://wiki.nci.nih.gov/download/attachments/13502514/NCIA+CTC+large+10+mm+polyps.xls This subset of the ACRIN 2600\+ total trial-accrued cases http://acrin.org/TabID/151/Default.aspxrecapitulates the incidence and polyp size proportions found in the general population. As a result of {color:black}data-sharing{color} by the ACRIN organization, NCI {color:black}provides{color} this collection {color:navy}to{color}the biomedical research community as a resource that may be used as a training set to improve current day computational methods for {color:black}colon polyp{color} screening{color:navy},{color}
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