Modified the ISA-TAB-Nano 1.1 version to address user comments. Modifications include:
Removal of the Material Linkage column from the Material File. The Material Constituent column identifies the materials that are linked if the Material Linkage Type is specified.
Fixes
Fixed Material File glossary, template, and examples to remove the Material Linkage column
Known Issues and Workarounds
Currently, ISA-TAB does not support Study Grant Number and Study Funding Agency as standard fields in the Investigation Files. These fields can be added in a comments field.
Grouping of assays is subjective to the particular study. Recommend grouping of assays that use the same sample under one study.
For studies involving insertion of tumor cells into mice and the application of a nanoparticle as a treatment, the tumor cells should be parameter values and the nanoparticle should be factor values.