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This section describes how to review or ascribe characterizations to samples that have been submitted to caNanoLab. This section includes the following topics:
You can perform the procedures described in this section only if you have curator status. If you have view only permissions, see 5 - Managing Sample Characterizations 2.1 DRAFT. |
Sample characterization, describing distinctive characteristics or essential features of the sample determined through analytical methods, records information associated with sample synthesis and properties. Samples can be characterized in caNanoLab by physical or chemical characteristics, or by data derived under in vitro and in vivo conditions.
In the Navigation Tree on the left sidebar, click the Characterization button. Five tabs showing characterization subcategories display on the page that opens. Select the Add button on the All tab that corresponds to the category of characterization annotations you want to add, or select the tab itself where you can add characterizations to the sample. The All tab displays any characterizations that have already been added to the sample; the characterization category tabs also display annotations specific to those categories.
You may have the option to add or delete function details with Add and Delete buttons. If you do not have certain security privileges, the Add and Delete buttons are hidden, and you have read-only access to the existing items. |
Follow the links below for more information about entering characterization information for the sample of interest:
See also 5 - Managing Sample Characterizations 2.1 DRAFT
The page that opens after you click an Add button to add a characterization is very similar for all characterization types. The page differs only in the Properties section if there are special properties driven by the selection of characterization names. They also differ in the drop-down values for the column name in the Finding section driven by the characterization name and assay type selections.
Follow the links below for more information about entering characterization information for the sample of interest:
After you click the Characterizations button on the Navigation Tree, on the All tab click the Add button associated with Physico-Chemical Characterizations or select the Physico-Chemical Characterization tab where you can also click the Add button to add characterizations. The Physico-Chemical Characterization subcategory allows you to enter physical or chemical characterizations for the nanomaterial component of the sample.
The page that opens is organized into five sections. This page is the same for all physico-chemical characterizations, except for slight customizations based what you select in the Characterization Type* field. Instructions for using the page are outlined in the steps below.
To continue defining Physico-Chemical Characterization fields, follow these steps.
After defining the summary, continue the process described in 5 - Managing Sample Characterizations 2.1 DRAFT.
The [Characterization] Properties section opens only for the characterizations listed in the table below. To define properties for the characterizations, complete the fields as described in the following table.
Characterization | Property Fields | Field Options |
Physical State | Type | Select the appropriate type from among the following options: |
Shape Properties | Type (required) | Select from the drop-down list the appropriate shape type: |
Shape Properties | Aspect Ratio | Enter the shape aspect ratio. |
Shape Properties | Minimum,/Maximum Dimensions | Enter the minimum and maximum dimensions of the sample, as well as the units of measurement. |
Solubility Properties | Solvent | Select from the options or enter the name.
|
Solubility Properties | Critical Concentration | Enter appropriate values for the critical concentration, then select the appropriate units for those values |
Solubility Properties | Is Soluble? | Select Yes or No as to whether the solvent is soluble. |
Surface Properties | Is Hydrophobic? | Indicate with Yes or No whether the surface is hydrophobic. |
After defining the [characterization] properties, continue the process described in 5 - Managing Sample Characterizations 2.1 DRAFT.
In the Design and Methods sections, complete the fields as described in the following table.
Design and Methods Field | Description |
Description | Enter design and methods information not covered by other fields on the form. |
Technique and Instrument | |
Technique* | |
Abbreviation | |
Description | Enter an appropriate description for the characterization design and methods. |
Instrument |
Once you enter the data, click Save to save the information to the sample or Cancel to close the mini-window without saving data.
Continue the process described in 5 - Managing Sample Characterizations 2.1 DRAFT.
In the Finding sections, you can add one or more publications relevant to the sample as well as data derived for the sample. You can add as many files and derived data as you wish, or you can add derived data without adding files.
Click Add to expand the section, then complete the instructions as described in 5 - Managing Sample Characterizations 2.1 DRAFT and 5 - Managing Sample Characterizations 2.1 DRAFT.
In the Data and Conditions segment of the window, you can create a matrix where you can enter data values and/or other information such as laboratory conditions like pH or temperature that are part of your findings.
To define the data and condition matrix, follow these steps.
Column Type "Datum" is selected with this characterization | Autopopulated Column Name Option[s] |
Molecular Weight | |
Purity | |
Relaxivity | |
Size | |
Surface |
After adding data and conditions to the sample, continue the process described in 5 - Managing Sample Characterizations 2.1 DRAFT.
After adding one or more files, continue by 5 - Managing Sample Characterizations 2.1 DRAFT or if you have no derived data to add, return to the steps described in 5 - Managing Sample Characterizations 2.1 DRAFT.
After you click the Characterizations button on the Navigation Tree, on the All tab click the Add button associated with In Vitro Characterizations or select the In Vitro Characterization tab where you can also click the Add button to add characterizations. The In Vitro Characterization subcategory allows you to add characterizations for the nanomaterial component of the sample that were derived from analytical techniques performed under in vitro conditions.
The page that opens is organized into five sections. This page is the same for all in vitro characterizations, except for slight customizations based what you select in the Characterization* field. Instructions for using the page are outlined in the steps below.
To continue defining this characterization, follow these steps:
After defining the summary, continue the process described in 5 - Managing Sample Characterizations 2.1 DRAFT.
Specify one of the following in vitro Assay Type options or select [Other] to open a window where you can add a new assay type.
Characterization Selection | Assay Type Corresponding to Characterization |
---|---|
Blood Contact | |
Cytotoxicity | |
Immune Cell Function | |
Oxidative stress | |
Sterility | |
Targeting | |
Transfection | Click [Other] to add an assay type. |
The [Characterization] Properties section opens only when you select the following characterizations in the Summary section. To define properties for each unique characterization, enter information for the following fields.
After defining the [characterization] properties, continue the process described in 5 - Managing Sample Characterizations 2.1 DRAFT.
In the Design and Methods sections, complete the fields as described in the following table:
Design and Methods Field | Description |
Technique and Instrument | |
Technique* | |
Abbreviation | |
Description | Enter an appropriate description for the characterization design and methods. |
Instrument |
Once you enter the data, click Save to save the information to the sample or Cancel to close the mini-window without saving data.
Continue the process described in 5 - Managing Sample Characterizations 2.1 DRAFT.
In the Finding sections, you can add one or more publications relevant to the sample as well as data derived for the sample. You can add as many files and derived data as you wish, or you can add derived data without adding files.
Click Add to expand the section, then complete the instructions as described in 5 - Managing Sample Characterizations 2.1 DRAFT and 5 - Managing Sample Characterizations 2.1 DRAFT.
In the Data and Conditions segment of the window, you can create a matrix where you can enter data values and/or other information such as laboratory conditions that are part of your findings.
To define the matrix for the data, follow these steps.
Column Type "Datum" is selected with this characterization | Autopopulated Column Name Option[s] |
Enzyme Induction |
After adding data and conditions to the sample, continue the process described in 5 - Managing Sample Characterizations 2.1 DRAFT.
After adding one or more files, continue by or if you have no derived data to add, continue the process described in .
After you click the Characterizations button on the Navigation Tree, on the All tab click the Add button associated with In Vivo Characterizations or select the In Vivo tab where you can also click the Add button to add characterizations. The In Vivo Characterization subcategory allows you to add characterizations for the nanomaterial component of the sample that were derived from analytical techniques performed under in vivo conditions.
The page that opens is organized into five sections. This page is the same for all in vivo characterizations. Instructions for using the page are outlined in the steps below.
To continue defining Summary fields, follow these steps.
After defining the summary, continue the process described in 5 - Managing Sample Characterizations 2.1 DRAFT.
In the Design and Methods sections, complete the fields as described in the following table.
Design and Methods Field | Description |
Description | Enter information not covered by other fields on the form. |
Technique and Instrument | |
Technique* | |
Abbreviation | |
Description | Enter an appropropriate description for the design and methods. |
Instrument |
Once you specify the data, click Save to save the information to the sample or Cancel to close the mini-window without saving data.
Continue the process described in 5 - Managing Sample Characterizations 2.1 DRAFT.
In the Finding sections, you can add one or more publications relevant to the sample as well as data derived for the sample. You can add as many files and derived data as you wish, or you can add derived data without adding files.
Complete the instructions as described in 5 - Managing Sample Characterizations 2.1 DRAFT and 5 - Managing Sample Characterizations 2.1 DRAFT.
In the Data and Conditions segment of the window, you can create a matrix where you can enter data values and/or other information that are part of your findings.
To define the matrix for the data, follow these steps:
For an in vivo characterization, click [Other] to name the column yourself.
After adding data and conditions to the sample, continue the process described in .
After adding one or more files, continue by 5 - Managing Sample Characterizations 2.1 DRAFT or if you have no derived data to add, return to the steps described in 5 - Managing Sample Characterizations 2.1 DRAFT.
Sample characterization, describing distinctive characteristics or essential features of the sample determined through analytical methods, records information associated with sample synthesis and properties. Samples can be characterized in caNanoLab by physical or chemical characteristics, or by data derived under in vitro and in vivo conditions.
To view a sample characterizations summary, follow these steps:
caNanoLab lists characterizations that have been added to a sample under their corresponding Physical, In Vitro and In Vivo Characterization subcategories when you select the Characterization button on the Navigation Tree.
See also 5 - Managing Sample Characterizations 2.1 DRAFT.
If you have read only permissions, you will be able to view characterization but not perform associated tasks |
From a characterization summary page, and with curator privileges, you can perform the following tasks:
To print a characterization, follow these steps:
If buttons described in this section do not display, then you can assume that you have read-only access to the data. |
To export a characterization, follow these steps:
If buttons described in this section do not display, then you can assume that you have read-only access to the data. |
To edit a characterization, follow these steps:
If buttons described in this section do not display, then you can assume that you have read-only access to the data. |
The characterization files and/or derived data for this sample can be copied to other samples from the same primary point of contact.
To copy characterizations, open the sample characterization form that displays the characterization, and follow these steps:
If buttons described in this section do not display, then you can assume that you have read-only access to the data. |
To delete a characterization for a selected sample, follow these steps:
This only deletes the characterization(s) for the selected sample. If the characterization(s) is copied for other samples, the characterization will not be deleted. |
Deleted characterizations are placed in the sample archive for history purposes.
If buttons described in this section do not display, then you can assume that you have read-only access to the data. |
gation Tree button for an open sample, a Publication[s] summary page displays those publications associated with the sample, and the publication identifier, title, authors and year, where appropriate. Additionally, each publication category tab displays its corresponding publications.
Either on the Publications All tab or the subcategory tabs, you can perform these tasks:
If you work from the Publications menu option, you can associate multiple samples with a publication. See Managing Publications. Alternatively, if you add publications to an open sample using the Navigation Tree option, you can use the copy feature to associate the publication with other samples in the same way you copy characterizations to multiple samples. See 5 - Managing Sample Characterizations 2.1 DRAFT.
For more information about adding a publication, see Submitting a Publication.
For information about document details, see Searching Publications and other document topics in the Managing Publications section .
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