The NCI caDSR CDE Browser can be used to download collections of meta data describing data held in repositories for cancer research and clinical trials, and the caDSR Form Builder can be sued to view and download the Case Report (CRF) designs. These CDEs can be downloaded in Excel or XML Format, form can be downloaded in Excel format. However, it is not always easy to find the desired collection, as the high level organization of CDEs and Forms in the Navigation Tree is by Context, not topic. After selecting a Context, one can browse the Classifications, but this may not be intuitive to some users.
Additionally, attempting to download all the caDSR CDEs would result in a file that is too large for a single MS Excel download.
Therefore, "canned", or pre-downloaded collections in the following CDEs are provided for your convenience.
The NCI develops and publishes standard CRF templates for use in creating new clinical trials protocol forms. Each CRFs consists of CDEs organized into 3 sections: mandatory, optional, and conditional CDEs. To retrieve these and any other forms registered in caDSR since the dates listed below, please visit the caDSR Form Builder, where a Guest account and passcode are provided for your convenience.
Adverse Event and Series Adverse Event NCI CRF Standards created on September 5th, 2014
Concomitant Medication NCI CRF Standards created on September 5th, 2014
Consent NCI CRF Standards created on October 4th, 2013
CT Image Acquisition NCI CRF Standards created on December 9th, 2013
CT Imaging Agent NCI CRF Standards created on December 9th, 2013
Demography NCI CRF Standards created on March 22nd, 2013
Diagnosis NCI CRF Standards created on December 9th, 2013
Diagnosis Administrative NCI CRF Standards created on October 4th, 2013
Diagnosis Gross Pathology NCI CRF Standards created on December 9th, 2013
Diagnosis Intervention NCI CRF Standards created on January 7, 2014
TCGA (The Cancer Genome Atlas) is a project funded by the National Cancer Institute (NCI) and National Human Genome Research Institute (NHGRI). A project overview can be found on the TCGA Home Page.
TCGA provides data element descriptions for the clinical data elements found in the TCGA data files. The BCR on-line data dictionary displaying the essentials of the clinical CDEs as an HTML page is located here. The files below contain all the caDSR metadata for these CDEs. The HTML data dictionary was generated from the XML download of the TCGA CDEs. For more information or help creating your own HTML Data Dictionary from NCI registered CDEs, please contact the NCI Help Desk.
They are also available from the CDE Browser in the caBIG Context under the Classifications tab heading "TCGA 2.6 by Disease". New TCGA CDEs not yet in the BCR data dictionary can be found under the caBIG Classification "The Cancer Genome Atlas", sub-heading "New TCGA Data Elements"
NAACCR develops and promotes uniform data standards for cancer registration, and aggregates and publishes data from central cancer registries. It promotes the use of cancer surveillance data and systems for cancer control and epidemiological research. See their website for more information about NAACCR.
NCI has registered several versions of the NAACCR data elements as CDE metadata in caDSR for discovery and use by those wishing to utilize the NAACCR data, or create data repositories of compatible data.
The following collections have been recorded in caDSR, are available from the CDE Browser in the PS&CC Context under the Classifications tab heading "Division of Cancer Control and Population Sciences". They have been downloaded and made available here for convenience.
The SEER program works to provide information on cancer statistics in an effort to reduce the burden of cancer among the U.S. population. The data elements collected in cancer survellance have been registered in the NCI caDSR, and are available from the CDE Browser in the PS&CC Context under the Classifications tab heading "caSEER", subheading "com.imsweb.caseer". They have been downloaded and made available here for convenience.
BRIDG is a model that was created by a collaborative effort engaging stakeholders from the Clinical Data Interchange Standards Consortium (CDISC), the HL7 BRIDG Work Group, the US National Cancer Institute (NCI), and the US Food and Drug Administration (FDA). A logical information model was developed to describe basic, pre-clinical, clinical, and translational research. Please visti the BRIDG web stie for more information.
The CDEs in the BRIDG model are available from the CDE Browser in the BRIDG Context under the Classifications heading "Link to BRIDG 3.2", subheading "BRIDG 3.2". They have been downloaded and made available here for convenience.
BRIDG 3.0.2 is also available in the Attachments section of this page and in the CDE Browser.
For prior versions of the files see the Attachments listed at the end of this page.
If importing caDSR content into another ISO/IEC 11179 registry, i.e. local implementation of cgMDR, please add the caDSR Registration Authority Identifier (RAI) 2.16.840.1.1138220.127.116.11 to the metadata to keep the caDSR content distinct from the local repository. Per ISO/IEC 11179, the RAI is part of a globally unique identifier known as the IRID (Item Registry Identifier), and uniquely identifies registry content as being related to particular registrars. The IRID for all caDSR content is the <caDSR OID + Item public Id + item version>. For example, if the caDSR item public id = 2181292, version = 1.1, when importing you would add the RAI, and the result would be an IRID = 2.16.840.1.113818.104.22.168 + 2181292 + 1.1.
The following lists the attachments to this page.