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The NCI caDSR CDE Browser can be used to download collections of meta data describing data held in repositories for cancer research and clinical trials.

The caDSR Form Builder can be used to create, view and download the Case Report Forms (CRFs) designs.

Currently, CDEs can be downloaded in Excel or XML Format, CRFs can be downloaded in Excel format.

It is not easy for occasional or novice user of the CDE Browser and Form Builder to discover collections of CDEs or CRFs, since the high level organization of CDEs and Forms in the Navigation Tree is by Context, not topic. After selecting a Context, one can browse the Classifications, but this may not be intuitive, and some find the use of the Advanced Search, which also offers search by Classifications, dauntingModernization of the caDSR content access services is planned.

In addition to the usability issues noted above, attempting to download all the caDSR CDEs would result in a file size that is too large for a single MS Excel download, and currently forms can only be downloaded one form at a time.

Therefore, "canned", or pre-downloaded collections in the following CDEs and CRFs are provided for your convenience.

caDSR logographic 6

 


  

          CDEs as Excel             CDEs as XML              CRF as Excel

NCI Standard CDEs

caDSR Community Released CDEs

Current NCI Standard CRFs

The NCI develops and publishes standard CRF templates for use in creating new clinical trials protocol forms.  Each CRFs consists of CDEs organized into 3 sections: mandatory, optional, and conditional CDEs. To retrieve these and any other forms registered in caDSR since the dates listed below, please visit the caDSR Form Builder, where a Guest account and password are provided for your convenience.

 

 

Project CDEs

CDEs are organized in the caDSR CDE Browser based on Context and Classification Scheme.  Opening up the Context name in the browser will reveal a "Classifications" node, that when opened will list all the projects in alphabetical order. Clicking on a project node will search for all CDEs used by the project.

TCGA Phase II meta data elements (CDEs)

TCGA (The Cancer Genome Atlas) is a project funded by the National Cancer Institute (NCI) and National Human Genome Research Institute (NHGRI). A project overview can be found on the TCGA Home Page.

TCGA provides data element descriptions for the clinical data elements found in the TCGA data files.  The BCR on-line data dictionary displaying the essentials of the clinical CDEs as an HTML page is located here.  The files below contain all the caDSR metadata for these CDEs.  The HTML data dictionary was generated from the XML download of the TCGA CDEs. For more information or help creating your own HTML Data Dictionary from NCI registered CDEs, please contact the NCI Help Desk.

They are also available from the CDE Browser in the caBIG Context under the Classifications tab heading "TCGA 2.6 by Disease".  New TCGA CDEs not yet in the BCR data dictionary can be found under the caBIG Classification "The Cancer Genome Atlas", sub-heading "New TCGA Data Elements"

North American Central Cancer Registries (NAACCR) meta data elements (CDEs)

NAACCR develops and promotes uniform data standards for cancer registration, and aggregates and publishes data from central cancer registries. It promotes the use of cancer surveillance data and systems for cancer control and epidemiological research. See their website for more information about NAACCR.

NCI has registered several versions of the NAACCR data elements as CDE metadata in caDSR for discovery and use by those wishing to utilize the NAACCR data, or create data repositories of compatible data.

The following versions of NAACCR have been recorded in caDSR, are available from the CDE Browser in the PS&CC Context under the Classifications tab heading "Division of Cancer Control and Population Sciences". They have been downloaded and made available here for convenience.

Surveillance, Epidemiology and End Results (SEER) meta data elements (CDEs)

The SEER program works to provide information on cancer statistics in an effort to reduce the burden of cancer among the U.S. population.  The data elements collected in cancer surveillance have been registered in the NCI caDSR, and are available from the CDE Browser in the PS&CC Context under the Classifications tab heading "caSEER", subheading "com.imsweb.caseer". They have been downloaded and made available here for convenience.

Biomedical Research Integrated Domain Group (BRIDG) meta data elements (CDEs)

BRIDG is a model that was created by a collaborative effort engaging stakeholders from the Clinical Data Interchange Standards Consortium (CDISC), the HL7 BRIDG Work Group, the US National Cancer Institute (NCI), and the US Food and Drug Administration (FDA). A logical information model was developed to describe basic, pre-clinical, clinical, and translational research.  Please visit the BRIDG website for more information.

The CDEs in the BRIDG model are available from the CDE Browser in the BRIDG Context under the Classifications heading "Link to BRIDG 3.2", subheading "BRIDG 3.2". They have been downloaded and made available here for convenience.

 BRIDG 3.0.2 is also available in the Attachments section of this page and in the CDE Browser.

National Biomedical Imaging Archive (NBIA)(formerly NCIA)

The CDEs in the HINTS 2005 survey are available from the CDE Browser in the caBIG Context under the Classifications heading "NBIA". They have been downloaded and made available here for convenience.

Health Information National Trends Survey (HINTS2005)

The CDEs in the HINTS 2005 survey are available from the CDE Browser in the PS&CC Context under the Classifications heading "HINTS2005". They have been downloaded and made available here for convenience.

eMerge Project

The CDEs in the eMerge project are available from the CDE Browser in the caBIG Context under the Classifications heading "eMerge Data Variables". They have been downloaded and made available here for convenience.

 

For prior downloaded versions of the files see the Attachments listed at the end of this page.

If importing caDSR content into another ISO/IEC 11179 registry, i.e. local implementation of cgMDR, please add the caDSR Registration Authority Identifier (RAI) 2.16.840.1.113883.3.26.2 to the metadata to keep the caDSR content distinct from the local repository. Per ISO/IEC 11179, the RAI is part of a globally unique identifier known as the IRID (Item Registry Identifier), and uniquely identifies registry content as being related to particular registrars. The IRID for all caDSR content is the <caDSR OID + Item public Id + item version>. For example, if the caDSR item public id = 2181292, version = 1.1, when importing you would add the RAI, and the result would be an IRID = 2.16.840.1.113883.3.26.2 + 2181292 + 1.1.

The following lists the attachments to this page.

REDx - caDSR REDCap Transformation Utilities

 

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